Ataxic Disorders

Ataxic Disorders

1st Edition - September 21, 2011

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  • Editors: Sankara Subramony, Alexandra Dürr
  • Hardcover ISBN: 9780444518927
  • eBook ISBN: 9780444534941

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This volume’s primary goal is to provide a comprehensive understanding of recent developments and advancements in the study of ataxic disorders. Beginning with an examination of the cerebellar region, and then progressing to a fresh perspective on the clinical aspects of the various forms of ataxia, this handbook gives clinicians a state-of-the-art reference for the management of the many etiologies and neurological manifestations of ataxic disorders. Clinicians will gain a broader understanding of generative ataxias and the genetic disorders associated with them. In addition, new neurophysiological and imaging techniques are discussed, along with an in-depth examination of the treatment and management protocols of ataxic diseases.

Key Features

  • A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology
  • International list of contributors including the leading workers in the field
  • Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care


Neuroscience research workers

Table of Contents

  • Foreword


    List of contributors

    Chapter 1: The cerebellum – structure and connections

    Chapter 2: Physiology of clinical dysfunction of the cerebellum

    Chapter 3: Oculomotor aspects of the hereditary cerebellar ataxias

    Chapter 4: Magnetic resonance and nuclear medicine imaging in ataxias

    Chapter 5: Neuropathology of degenerative ataxias

    Chapter 6: Approach to ataxic diseases

    Chapter 7: Acquired ataxias, infectious and para-infectious

    Chapter 8: Ataxia in patients with brain infarcts and hemorrhages

    Chapter 9: Ataxia resulting from posterior fossa tumors of childhood and other mass lesions

    Chapter 10: Nutritional cerebellar degeneration, with comments on its relationship to Wernicke disease and alcoholism

    Chapter 11: Immune-mediated acquired ataxias

    Chapter 12: Toxic agents causing cerebellar ataxias

    Chapter 13: Paraneoplastic cerebellar degeneration

    Chapter 14: Epidemiology and population genetics of degenerative ataxias

    Chapter 15: Sporadic adult-onset ataxia of unknown etiology

    Chapter 16: Overview of autosomal recessive ataxias

    Chapter 17: Friedreich ataxia

    Chapter 18: Ataxia with vitamin E deficiency and abetalipoproteinemia

    Chapter 19: Ataxia–telangiectasia

    Chapter 20: Autosomal recessive cerebellar ataxias with oculomotor apraxia

    Chapter 21: Other autosomal recessive and childhood ataxias

    Chapter 22: Ataxia in mitochondrial disorders

    Chapter 23: Fragile X-associated tremor/ataxia syndrome

    Chapter 24: Overview of autosomal dominant ataxias

    Chapter 25: Spinocerebellar ataxia type 1

    Chapter 26: Spinocerebellar ataxia type 2

    Chapter 27: Machado–Joseph disease/spinocerebellar ataxia type 3

    Chapter 28: Spinocerebellar ataxia type 5

    Chapter 29: Spinocerebellar ataxia type 6

    Chapter 30: Spinocerebellar ataxia type 7

    Chapter 31: Clinical and genetic features of spinocerebellar ataxia type 8

    Chapter 32: Spinocerebellar ataxia type 10

    Chapter 33: Spinocerebellar ataxia type 11

    Chapter 34: Spinocerebellar ataxia type 12

    Chapter 35: Spinocerebellar ataxia 13 and 25

    Chapter 36: Spinocerebellar ataxia type 14

    Chapter 37: Spinocerebellar ataxia type 15

    Chapter 38: Spinocerebellar ataxia type 20

    Chapter 39: Spinocerebellar ataxia type 28

    Chapter 40: Other spinocerebellar ataxias

    Chapter 41: Dentatorubral–pallidoluysian atrophy

    Chapter 42: Episodic ataxias 1 and 2

    Chapter 43: Ataxias related to sensory neuropathies

    Chapter 44: Frontal lobe ataxia

    Chapter 45: Balance and gait problems in the elderly

    Chapter 46: Treatment and management issues in ataxic diseases


Product details

  • No. of pages: 680
  • Language: English
  • Copyright: © Elsevier 2011
  • Published: September 21, 2011
  • Imprint: Elsevier
  • Hardcover ISBN: 9780444518927
  • eBook ISBN: 9780444534941

About the Editors

Sankara Subramony

Affiliations and Expertise

Professor of Neurology, McKnight Institute at the University of Florida, Gainesville, USA

Alexandra Dürr

Affiliations and Expertise

INSERM U289 et Département de Génétique Cytogénétique et Embryologie, Hôpital de la Salpêtrière, Paris, France

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