Interest in the functional roles of astrocytes in the nervous system has grown significantly as it is recognized that these cells not only have their own pharmacology but also release neuro- and vaso-active factors. This book relates astrocyte pharmacology to cell function for the first time, making it an attractive text across the neuroscience community.
- Discusses the pharmacological regulation of specific astrocyte functions
- Covers functional interactions between these and adjacent CNS cell types
- Examines regional heterogeneity of astrocytes with respect to receptor expression
- Compares in vitro and in vivo approaches
Neurobiologists, pharmacologists, neurologists, and biophysicists in research
S.W. Levison and J.E. Goldman, Astrocyte Origins. Astrocytes as Target Cells: K. McCarthy, K. Enkvist, and Y. Shao, Astroglial Adrenergic Receptors. B.R. Pearce, Amino Acid Receptors. G.P. Wilkin and D.R. Marriott, Biochemical Responses of Astrocytes to Neuroactive Peptides. G. Bruner, M.L. Simmons, and S. Murphy, Astrocytes: Targets and Sources for Purines, Eicosanoids, and Nitrosyl Compounds. A.T. Arenander and J. de Vellis, Early Response Gene Expression Signifying Functional Coupling of Neuroligand Receptor Systems in Astrocytes. S. Duffy and B. MacVicar, Voltage-Activated Ionic Channels in Astrocytes. Astrocyte Influences on Neurons: G.R. Dutton, Astrocyte Amino Acids: Evidence for Release and Possible Interactions with Neurons. H. Kimelberg, T. Jalonen and W. Walz, Regulation of the Brain Microenvironment: Transmitters and Ions. J.P. Schwartz, Neuropeptide Expression in Astrocytes. P.J. Magistretti, O. Sorg, and J-L. Martin, Regulation of Glycogen Metabolism in Astrocytes: Physiological, Pharmacological, and Pathological Aspects. J.S. Rudge, Astrocyte-Derived Neurotrophic Factors. Interactions between Astrocytes and with Other Cells in the CNS: A.M. Jensen and S-Y. Chiu, Astrocyte Networks. A.L. Gard, Astrocyte-Oligodendrocyte Interactions. E.N. Benveniste, Astrocyte-Microglia Interactions. P.A. Cancilla, J. Bready, and J. Berliner, Interactions between Astrocytes and Endothelial Cells in the Central Nervous System. P.E. McKeever, Human Astrocyte Neoplasms. References.
- No. of pages:
- © Academic Press 1993
- 26th February 1993
- Academic Press
- eBook ISBN: