This book updates the previous coverage of the mechanisms and mediators of asthma and its treatment. It presents articles by the foremost names in the field.
- Updates the previous coverage of the mechanisms and mediators of asthma and its treatment
- Presents articles by the foremost names in the field
- Includes over 92 figures and 12 tables
Research pharmacologists and chest physiologists with an interest in asthma. Clinical pharmacologists.
The Genetics and Epidemiology of Atopy and Asthma:
J.-L. Zhao, K.F. Austen, and B.K. Lam, Prospective on the Functional Characteristics of Human LTC4 Synthase.
W.O.C.M. Cookson, Genetics and Asthma.
I.M. Adcock and P.J. Barnes, Transcription Factors in Asthma.
U. Wahn, Environmental Factors in the Development of Atopy and Asthma in Children.
Signal Transduction in Immune and Inflammatory Cells:
M.-H. Jouvin and J.-P. Kinet, Expression and Function of the High-Affinity Receptor for IgE in Asthma.
J.T. Schroeder, D.W. MacGlashan, Jr., and L.M. Lichtenstein, The Role of Basophil-Cytokine Networks in Asthma.
A. Mantovani, A. Sica, S. Saccani, S. Orlando, N. Polentarutti, P. Allavena, and S. Sozzani, Regulation of Inflammatory Cytokine Receptor Expression by Pro- and Anti-Inflammatory Molecules.
H.R. Katz, The gp49 Family: A New Pathway for the Inhibition of Mast Cell Activation.
J.M. Langdon and S. MacDonald, Biologic Properties of the IgE-Dependent Histamine Releasing Factor.
Chemical Mediators in Allergic Disorders:
A.F. Walls, J.K. Shute, J. Warner, J.A. Cairns, P.H. Howarth, and S.T. Holgate, Mast Cell and Eosinophil Proteases in the Chronic Allergic Inflammatory Response.
M. Triggiani and G. Marone, Remodelling of Arachidonic Acid Pools in Inflammatory Cells Migrating into the Lung.
D. Proud, C.J. Reynolds, J.M. Bathon, and A. Faussner, Kinin Actions in the Human Airways: Modulation by Allergic Inflammation.
M. Baggiolini, M. Uguccioni, and P. Loetscher, Chemokines and Chemokine Receptors in Allergic Inflammation.
Molecular Regulation of Cytokine Genes:
S.N. Georas, T.F. Burke, R. Chen, J. Cumberland, and V. Casolaro, The Molecular Basis of IL-4 Dysregulation in the Atopic Condition.
D.J. Cousins, D.Z. Staynoff, and T.H. Lee, Regulation of IL-4, IL-5 and GM-CSF in T-Lymphocytes.
Immune and Inflammatory Cells in Allergic Disorders:
A.B. Kay, T-Lymphocytes in Chronic Asthma.
L.B. Schwartz, Mast Cells and Asthma.
G. Marone, Human Cardiac Mast Cells and Their Role in Severe Allergic Reactions.
G.J. Gleich, J. Bankers-Fulbright, S. Okada, H. Kita, and L.W. Hunt, Novel Glucocorticomimetic Agents Active on Eosinophils: Potential Uses in the Therapy of Asthma.
Biophysical and Immunological Alterations in Atopic Patients:
S. Seidenari, Biophysical Evaluation of Skin Reactivity in Atopic Patients.
E.W. Gelfand, G. Lack, A. Oshiba, and E. Hamelmann, Role of Allergen-Specific B Cells and IgE in the Development of Allergen-Driven Airway Hyperresponsiveness.
Cytokines and Inflammation in the Airways:
J.E. Gern, R.F. Lemanske, and W.W. Busse, Role of Rhinoviruses in Virus-Induced Asthma.
G. Ciprandi, G. Passalacqua, B. Azzarone, M. Bagnasco, and G.W. Canonica, Molecular Events in Allergic Inflammation: Expression of Adhesion Molecules and Their Modulation.
J.C. Hogg, V. Macek, A. Dakhama, S. Hayashi, and R.G. Hegele, The Prevalence of Common Respiratory Viral Nucleic Acid in Asthmatic and Non-Asthmatic Human Lungs.
Prospectives in Therapy of Allergic Disorders:
R.P. Schleimer and Q. Hamid, Regulation of Allergic Airways Inflammation by Cytokines and Glucocorticoids.
J.M. Drazen, Interfering with the 5-Lipoxygenase Pathway as a Novel Way to Treat Asthma.
J.A. Grant, New Aspects of Antihistamines in the Treatment of Asthma.
W.J. Metzger and J.A. Nyce, DNA Antisense Therapy for Asthma.
Prospectives in Immunotherapy of Allergic Disorders:
T.A.E. Platts-Mills, Prospectives in Allergen Specific Treatment.
P.S. Creticos, Peptide Downregulation of the Immune Repsonse.
E. Raz, Immune Deviation of the Allergic Response by DNA Immunization.
- No. of pages:
- © Academic Press 1998
- 1st May 1998
- Academic Press
- eBook ISBN:
Universita di Napoli Federico II, Italy
Stephen T. Holgate is a Clinical Professor of Immunopharmacology at Southampton General Hospital.
Southampton General Hospital, U.K.
National Heart and Lung Institute, London, U.K.
Johns Hopkins University, Baltimore, Maryland, U.S.A.
Harvard Medical School, Boston, MA, USA