Asbestos and Disease - 1st Edition - ISBN: 9780126360509, 9780323140072

Asbestos and Disease

1st Edition

Authors: Author Unknown
eBook ISBN: 9780323140072
Imprint: Academic Press
Published Date: 28th August 1978
Page Count: 549
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Description

Asbestos and Disease provides a much-needed comprehensive compendium and presentation of accumulated information on asbestos and disease. Organized into five parts, this book begins with the nature, occurrence, properties, mining, milling, manufacturing, and use of asbestos minerals. Some chapters follow on the identification, quantification, and environmental distribution of asbestos fibers. This book also tackles the asbestotic and neoplastic effects of asbestos. The pathogenic mechanisms, prevention, and control of asbestos are also addressed. This work will provide nonspecialists with easily comprehensible and meaningful data that will assist them in their endeavors in this field.

Table of Contents


Foreword

Preface

Part I Asbestos and Its Distribution

1 Historical Background

Early Beginnings

The Intermediate Years

The Breakthrough Period

Development of Manufacture and Use

Recognition of Pathogenicity

Appearance of Other Pathological Consequences

State of Medical Knowledge in the Early 1960's

2 Asbestos Minerals: Nature, Occurrence, and Properties

Geological Formation

Chemical Characteristics

Physical Characteristics

Grading

Talc

3 Mining, Milling, Manufacturing, and Use

Mining

Milling

Manufacturing

End Uses

Disposal of Wastes Containing Asbestos

4 Identification and Quantitation of Asbestos Fibers

Basic Considerations in Sampling of Airborne Dust

Collection of Airborne Dust Samples

Dust Examination by Light Microscopy

Dust Examination by Electron Beam Methods

Constraints on Electron Beam Methods: Ancillary Techniques

Determination of Asbestos in Tissue

Examination of Water and Food for Asbestos

5 Environmental Distribution

Asbestos in Air

Asbestos in Water

Asbestos in Food and Drugs

Asbestos in Consumer Products

Part II Asbestotic Effects

6 Basic Clinical Considerations

7 Characteristics and Etiology of Parenchymal Asbestosis

Definition

Pathology

Clinical Characteristics

Etiology

8 Characteristics and Etiology of Pleural Asbestosis

Definition

Pathology

Clinical Characteristics

Etiology

9 Prevalence, Diagnosis, and Course of the Asbestoses

Prevalence

Diagnosis

Clinical Course

Part III Neoplastic Effects

10 Characteristics and Etiology of Mesothelioma

Definition

Pathology

Clinical Manifestations

Etiology

11 Prevalance, Diagnosis, and Course of Mesothelioma

Prevalence

Diagnosis

Clinical Course

12 Characteristics, Etiology, and Prevalence of Asbestos-Associated Carcinoma

Definition

Special Features

Etiology

Prevalence

Part IV Pathogenic Mechanisms

13 Respiratory Portal of Entry

Anatomy

Physiology of Air Flow

Particle Desposition

Clearance

Effects of Disease and of Other Pollutants

14 The Gastrointestinal Tract and Other Portals of Entry

Sources of Alimentary Intake

Physical Situation at the Bowel Wall

Evidence for Penetration of Gastrointestinal Wall

Pathogenic Significance of Ingested Asbestos

Other Portals of Entry

15 General Tissue Reactions and Cytotoxicity

Some Problems

Movement of Fibers

Hemolytic Properties of Asbestos Fibers

In Vitro Cytotoxic Effects of Asbestos

Immunological Reactions

16 Phagocytosis and the Asbestos Body

Origin of Phagocytes

Process of Phagocytosis

Formation of Asbestos Bodies

17 Fibrogenesis and Tumorigenesis

Fibrogenesis from Asbestos

Tumorigenesis from Asbestos

Relation of Pathogenesis to Fiber Size

Part V Prevention and Control

18 Regulatory Principles and Objectives

Information Required for Formulation of Criteria

Status of Information on Asbestos

19 Examples of National Regulatory Development

Development of Standards in the United States

Development of Workplace Standards in Great Britain

Notes on Action Taken in Other Countries

20 Procedures for Prevention and Control

Substitution of Less Hazardous Materials

Suppression of Dust at Source

Rapid Removal

Personal Protection

Other Action

Supervision

Education

Bibliography

Addendum

Subject Index


Details

No. of pages:
549
Language:
English
Copyright:
© Academic Press 1978
Published:
Imprint:
Academic Press
eBook ISBN:
9780323140072

About the Author

Author Unknown