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Artificial Protein and Peptide Nanofibers - 1st Edition - ISBN: 9780081028506, 9780081028513

Artificial Protein and Peptide Nanofibers

1st Edition

Design, Fabrication, Characterization, and Applications

Editors: Gang Wei Sangamesh Kumbar
eBook ISBN: 9780081028513
Paperback ISBN: 9780081028506
Imprint: Woodhead Publishing
Published Date: 24th July 2020
Page Count: 502
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Table of Contents

Section A Fabrication and characterizations of artificial protein and peptide nanofibers

1Section A Fabrication and characterizations of artificial protein and peptide nanofibers

1 Supramolecular self-assembly: A facile way to fabricate protein and peptide nanomaterials Luyang Zhao, Xuehai Yan

2 Self-assembly formation of peptide and protein nanofibers on surfaces and at interfaces
Shuwei Sun, Zhiqiang Su, Gang Wei

3 Fabrication of amyloid nanofiber matrices by electrospinning
Devina Jaiswal, Sara Katebifar, Swetha Rudraiah, Sangamesh G. Kumbar

4 Novel protein and peptide nanofibrous structures via supramolecular co-assembly
Christian Helbing, Klaus D. Jandt

5 Characterization techniques of protein and peptide nanofibers: Self-assembly kinetics
Gang Wei

Section B Enhanced functions of nanofibers by sequence design and modification

6 Protein synthesis and characterization
Shobhit Kadakeri, Michael R. Arul, Rosalie Bordett, Nithyadevi Duraisamy, Hemantkumar Naik, Swetha Rudraiah

7 Design of functional peptide nanofibers based on amyloid motifs
Wenfeng Wei, Zhiqiang Su

8 Design of amphiphilic peptide nanofibers
Mustafa O. Guler

9 Nanofiber matrices of protein mimetic bioactive peptides for biomedical applications
Allen Zennifer, Muthu Parkkavi Sekar, Anuradha Subramanian, Swaminathan Sethuraman

10 Synergetic integration of computer-aided design, experimental synthesis, and self-assembly for the rational design of peptide/protein nanofibrils
Ke Zheng, Jing Ren, Yawen Liu, Shengjie Ling

11 Composite nanofiber matrices for biomedical applications
Ramya Dhandapani, Amrutha Manigandan, Swaminathan Sethuraman, Anuradha Subramanian

12 Nanofiber-based hydrogels and aerogels
Li Sun, Aiguo Wu

Section C Related applications of artificial protein and peptide nanofibers

13 Protein and peptide nanostructures for drug and gene delivery
Uma Maheswari Krishnan

14 Protein and peptide nanofiber matrices for the regenerative medicine
Seyed Mohammad Mir, Aneela Anwar, Ibrahim Dulijan, Alok Kumar, Xiaojun Yu

15 Fibrous scaffolds for bone tissue engineering
Jennifer Moy, Apurva Limaye, Treena Livingston Arinzeh

16 Assembled peptides for biomimetic catalysis
Mengfan Wang, Wei Qi

17 New protein-based smart materials
Lei Wang, Xin Huang

18 Nanofibers for soft-tissue engineering
Sama Abdulmalik, Sara Katebifar, Jonathan Nip, Laurie Yousman, Paulina Szarejko, Jiana Baker, Swetha Rudraiah, Sangamesh G. Kumbar


Artificial Protein and Peptide Nanofibers: Design, Fabrication, Characterization, and Applications provides comprehensive knowledge of the preparation, modification and applications of protein and peptide nanofibers. The book reviews the synthesis and strategies necessary to create protein and peptide nanofibers, such as self-assembly (including supramolecular assembly), electrospinning, template synthesis, and enzymatic synthesis. Then, the key chemical modification and molecular design methods are highlighted that can be utilized to improve the bio-functions of these synthetic fibers. Finally, fabrication methods for key applications, such as sensing, drug delivery, imaging, tissue engineering and electronic devices are reviewed.

This book will be an ideal resource for those working in materials science, polymer science, chemical engineering, nanotechnology and biomedicine.

Key Features

  • Reviews key chemical modification and molecular design methods to improve the bio-functions of synthetic peptide and protein nanofibers
  • Discusses the most important synthesis strategies, including supramolecular assembly, electrospinning, template synthesis and enzymatic synthesis
  • Provides information on fabrication of nanofibers for key applications such as sensing, imaging, drug delivery and tissue engineering


Materials Scientists working in biomaterials, nanotechnology, and polymer science. Chemists and Biochemists might also find the book helpful.


No. of pages:
© Woodhead Publishing 2020
24th July 2020
Woodhead Publishing
eBook ISBN:
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Ratings and Reviews

About the Editors

Gang Wei

Gang Wei received his Ph.D from Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, China, in 2007. Following the doctoral studies, he worked as the Alexander-von-Humboldt (2007) and Carl-Zeiss (2009) Postdoctoral Fellow at the Friedrich-Schiller-University of Jena, Germany. Since 2012, he has worked as a senior researcher and group leader in Hybrid Materials Interfaces Group at the University of Bremen, Germany. Since Feb 2018, he has been appointed as a guest professor at the Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences. His research interests include supramolecular self-assembly, biomimetic materials, two-dimensional nanomaterials, sensors and biosensors, as well as single molecule force spectroscopy. Up to now, he has published 100+ peer-reviewed papers in the journals like Chem. Soc. Rev., Prog. Polym. Sci., ACS Nano, Adv. Funct. Mater., Nanoscale Horizons, Nanoscale, Chem. Commun., J. Mater. Chem. B, and others.

Affiliations and Expertise

Group Leader and Senior Researcher, University of Bremen, Bremen, Germany

Sangamesh Kumbar

Dr. Kumbar is an Assistant Professor in the Departments of Orthopaedic Surgery, Materials Science & Engineering and Biomedical Engineering at the University of Connecticut. His research is focused on synthesis and characterization of novel biomaterials for tissue engineering and drug delivery applications. These polymeric materials namely polysaccharides, polyphosphazenes, polyanhydrides, polyesters as well as blends of two or more of the polymeric materials and composites combining the polymeric materials with ceramics in the form of 3-dimentional porous structures will serve as scaffolds for variety of tissue engineering applications. Dr. Kumbar is an active member of Society for Biomaterials (SFB), Controlled Release Society (CRS), Materials Research Society (MRS) and Orthopaedic Research Society (ORS). Dr. Kumbar is serving as a reviewer for more than 25 journals in the field of biomaterials, drug delivery and tissue engineering. He has recently edited a book “Natural and Synthetic Biomedical Polymers” Elsevier Science & Technology, 2014- ISBN: 978-0-12-396983-5. He is also on the Editorial Board of more than 7 journals in the area of his expertise including Journal of Biomedical Materials Research-Part B, Journal of Applied Polymer Science, and Journal of Biomedical Nanotechnology.

Affiliations and Expertise

University of Connecticut Health Center, USA