Description

The book contains contributions concerning the application of the new instrumental and methodological developments in omics technologies, including those related to Genomics, Transcriptomics, Proteomics, Peptidomics and Metabolomics, Lipidomics and Foodomics.
The16 chapters discuss in detail: innovative applications of functional gene microarrays for profiling microbial communities, microRNA profiling, novel genotyping applications using microarray technology in cancer research, next-generation sequencing applied to the study of human microbiome, emerging RNA-SEQ applications in food science, recent progress in plant proteomics, applications of gel-free proteomic approaches, the challenges and applications of proteomics tools for food authenticity, the role of salivary peptidomics in clinical applications, metabolomic approaches to the study of degenerative, cardiovascular and renal diseases, and neonatal medicine. Also covered are other omics applications such as profiling of genetically modified organisms, the fundamentals, applications and challenges of foodomics, and MS-based lipidomics. Moreover, this volume includes relevant and updated aspects on bioinformatics, data treatment, data integration and systems biology.
This book complements the previous volume "Fundamentals of Advanced Omics Technologies: New Advances from Genes to Metabolites" that covered the fundamental aspects of these new omics technologies.

Key Features

  • Describes the latest applications of omics technologies
  • Provides an excellent reference for applications of advanced omics techniques
  • Includes advanced tools and methodologies for dealing with the data generated

Readership

Analytical scientists, PhD students and technicians in control laboratories, universities, hospitals, research laboratories and regulation agencies

Table of Contents

  • Dedication
  • Contributors to Volume 64
  • Series Editor's Preface
  • Preface
  • Part I: Genomics and Transcriptomics
    • Chapter 1: Applications of Functional Gene Microarrays for Profiling Microbial Communities
      • Abstract
      • 1 Introduction
      • 2 Comparison of Microarrays with High-Throughput Sequencing
      • 3 Functional Gene Arrays
      • 4 Key Issues in Microarray Application
      • 5 Future Advancements
      • 6 Conclusions
      • Acknowledgments
    • Chapter 2: microRNA Profiling: An Overview of Current Technologies and Applications
      • Abstract
      • 1 Introduction
      • 2 miRNA Biogenesis and Nomenclature
      • 3 Considerations for miRNA Profiling
      • 4 miRNA Extraction
      • 5 qPCR Analysis of miRNAs
      • 6 Microarray Profiling of miRNAs
      • 7 Small RNA-seq
      • 8 In Silico miRNA Analysis Resources
      • 9 miRNA Functional Analysis
      • 10 Recent Developments in the Application of miRNA Profiling to Cancer Research
      • 11 Conclusions
    • Chapter 3: Application of Novel Genotyping Microarray Technologies in Cancer Research
      • Abstract
      • 1 Introduction
      • 2 Cancer Genetics: From Biology to Clinical Practice
      • 3 Genotyping Technologies
      • 4 Next-Generation Genomic Techniques
      • 5 Applications of Novel SNP Technologies in Cancer Research
      • 6 Conclusions and Future Directions
    • Chapter 4: Applications of Next-Generation Sequencing Technologies to the Study of the Human Microbiome
      • Abstract
      • 1 Introduction
      • 2 Next-Generation Sequencing
      • 3 Bioinformatics
      • 4 The Microbiome in Health and Disease
    • Chapter 5: Emerging RNA-Seq Applications in Food Science
      • Abstract
      • 1 Introduction
      • 2 Overview of RNA-Seq Technology
      • 3 Applications of RNA-Seq
      • 4 RNA-Seq in Food Science

Details

No. of pages:
496
Language:
English
Copyright:
© 2014
Published:
Imprint:
Elsevier
Print ISBN:
9780444626509
Electronic ISBN:
9780444626691