Apoptotis: Pharmacological Implications and Therapeutic Opportunities
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Programmed cell death (PCD) has become a topic of widespread interest and experimentation over the past decade. Written by experts in the field,Apoptosis: Pharmacological Implications and Therapeutic Opportunities concentrates on presenting an overview of PCD pathways as they are currently understood, and strives to identify important unanswered questions as well as other therapeutic possibilities suggested by recent biochemical discoveries. Understanding the biochemical pathways that participate in the cell death process has become an important goal in developmental biology, neurobiology, cardiology, and infectious disease research. The control of apoptosis has also become a major area of investigation in the field of cancer biology.Apoptosis: Pharmacological Implications and Therapeutic Opportunities contains an overview for those with a general interest in apoptosis, and provides discussions of sufficient depth to be useful for specialists in the field.
Readership
Students and researchers in pharmacology, biochemistry, and other biomedical disciplines. Academic neurologists, neuroscientists, and immunologists.
Table of Contents
- S.J. Webb, D.J. Harrison, and A.H. Wylie, Apoptosis: An Overview of the Process and Its Relevance in Disease. S. Desnoyers and M.O. Hengartner, Apoptosis: Pharmacological Implications and Therapeutic Opportunities.J.A. Hickman, H. Beere, and C. Dive, Methods for the Study of Apoptosis. A. Takahashi and W.C. Earnshaw, In vitro Systems for the Study of Apoptosis. C.M. Eischen and P.J. Leibson, The Fas Pathway in Apoptosis. M.J. Smyth, L.M.Obeid, and Y.A. Hannun, Ceramide: A Novel Lipid Mediator of Apoptosis. N.A. Thornberry, A. Rosen, and D.W. Nicholson, Control of Apoptosis by Proteases. D.S. Ucker, Death and Dying in the Immune System. W.S. May, Jr., Control of Apoptosis by Cytokines. C.W. Distelhorst, Glucocorticoid-Induced Apoptosis. A.D. Badley, D. Dockrell, and C.V. Paya, Apoptosis in AIDS. J.M. Hardwick, Virus-Induced Apoptosis. I. Nishimoto, T. Okamoto, U. Giambarella, and T. Iwatsubo, Apoptosis in Neurodegenerative Diseases. R.E. Buttyan, Apoptosis and the Response to Renal Damage. S.R. Umansky and L.D. Tomei, Apoptosis in the Heart. F. Que and G.J. Gores, Apoptosis and the Gastrointestinal System. C.E. Canman and M.B. Kastan, Role of p53 in Apoptosis. P.W. Mesner, Jr., I.W. Budihardjo, and S.H. Kaufmann, Chemotherapy-Induced Apoptosis. A. Samali, A.M. Groman, and T.G. Cotter, Role of Bcr-Abl Kinase n Resistance to Apoptosis. S.R. Denmeade, D.E. McCloskey, I.B.J.K. Joseph, H.A. Hahm, J.T. Isaacs, N.E. Davidson, Apoptosis in Hormone-Responsive Malignancies. Chapter References. Subject Index.
Product details
- No. of pages: 614
- Language: English
- Copyright: © Academic Press 1997
- Published: June 16, 1997
- Imprint: Academic Press
- eBook ISBN: 9780080581330
About the Serial Editor
J. August
Affiliations and Expertise
John Hopkins University; Department of Pharmacology, Baltimore, Maryland, U.S.A.
About the Serial Volume Editor
Stefan Kaufmann
Affiliations and Expertise
Max Planck Institute for Infection Biology, Berlin, Germany
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