Antiphospholipid Syndrome in Systemic Autoimmune Diseases

Antiphospholipid Syndrome in Systemic Autoimmune Diseases

1st Edition - April 1, 2009
There is a Newer Edition Available
  • Editors: R. Cervera, Joan Carles Reverter, Munther Khamashta
  • eBook ISBN: 9780080932347

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Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy and memory loss and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, from psychiatry to orthopedics.This book provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved as well as clinical manifestations in both “the thrombotic” and “non-thrombotic” manifestations of this important disease.

Key Features

* Comprehensive review of this major disease
* Includes information on treatment options available


Immunologists, rheumatologists, obstetricians, haematologists, fellows, medical student and those working in internal medicine and general medicine. As well as medical/scientific management and pharmaceutical companies.

Table of Contents

  • Classification and Epidemiology of the Antiphospholipid Syndrome;
    Laboratory Heterogeneity of the Antiphospholipid Antibodies:
    Pathogenesis of the Antiphospholipid Syndrome;
    Immunogenetics of the Antiphospholipid Syndrome;
    Systemic Manifestations of the Antiphospholipid Syndrome;
    Obstetric Manifestations of the Antiphospholipid Syndrome;
    Antiphospholipid Antibodies and Infections and Drugs;
    Antiphospholipid Antibodies and Malignancies;
    Antiphospholipid Antibodies and Vascular Disorders (Atheromatosis and Vasculitis);
    Treatment of the Antiphospholipid Syndrome;
    Difficult situations in the Antiphospholipid Syndrome;

Product details

  • No. of pages: 266
  • Language: English
  • Copyright: © Elsevier Science 2009
  • Published: April 1, 2009
  • Imprint: Elsevier Science
  • eBook ISBN: 9780080932347
  • About the Editors

    R. Cervera

    Affiliations and Expertise

    Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Spain

    Joan Carles Reverter

    Affiliations and Expertise

    Servei d'Hemoterapia i Hemostasia, Hospital Clinic, Barcelona, Spain

    Munther Khamashta

    Munther Khamashta
    Munther Khamashta is Professor/Consultant Physician and Director of The Graham Hughes Lupus Research Laboratory at St Thomas’ Hospital, London, and runs a large lupus pregnancy clinic. He studied medicine in Barcelona and internal medicine in Madrid, Spain, where he developed an interest in connective tissue diseases and received his PhD. He was awarded the MRCP in 1999 and FRCP in 2002. He joined the Lupus Unit in London 25 years ago and has been instrumental in developing it into an internationally recognised tertiary centre receiving referrals from all over the UK, see

    Affiliations and Expertise

    Graham Hughes Lupus Research Laboratory, The Rayne Institute, St. Thomas’ Hospital, London, England, UK