Description

Antioxidant Food Supplements in Human Health discusses new discoveries in the areas of oxygen and nitric oxide metabolism and pathophysiology, redox regulation and cell signaling, and the identification of natural antioxidants and their mechanisms of action on free radicals and their role in health and disease. An essential resource for researchers, students, and professionals in food science and nutrition, gerontology, physiology, pharmacology, and related areas.

Key Features

@introbul:Key Features @bul:* Health effects of antioxidant nutrients * Nutrients of vitamins C and E, selenium, alpha-lipoic acid, coenzyme Q10, carotenoids, and flavonoids * Natural source antioxidants, including pine bark, ginko biloba, wine, herbs,uyaku, and carica papaya

Readership

Clinical researchers, nutritionists, gerontologists, physiologists, and pharmacologists.

Table of Contents

Health Effects of Antioxidant Nutrients: P. Knekt, Vitamin E and Lung Cancer Prevention. G. Duthie, Natural Antioxidants in the Protection Against Cigarette Smoke Injury. Nutrients: Vitamins C and E: G.G. Block, Emerging Role of Nutrition in Chronic Disease Prevention: A Look at the Data, with an Emphasis on Vitamin C. M.G. Traber, E.A. Servinova, and L. Packer, Biological Activities of Tocotrienols and Tocopherols. N.K. Özer, S. Taha, A. Stocker, and A. Azzi, Effects of High Cholesterol, Vitamin E, and Probucol on Protein Kinase C Activity and Proliferation of Smooth Muscle Cells. H. Sies, L.-O. Klotz, V.S. Sharov, A. Assman, and K. Briviba, A New Function for Selenoproteins: Peroxynitrite Reduction. M. Maiorino, Selenium-Peroxidases in Mammalian Testis. a-Lipoic Acid. C.K. Sen, S. Roy, and L. Packer, a-Lipoic Acid: Cell Regulatory Function and Potential Implications. J.K. Lodge and L. Packer, Natural Sources of Lipoic Acid in Plant and Animal Tissues. T. Konishi and L. Packer, Determination of Protein Bound Lipoic Acid in Tissues by Enzyme Recycling Method. Coenzyme Q10: E. Cadenas, J.J. Poderoso, F. Antunes, and A. Boveris, Reaction of Ubiquinols with Nitric Oxide. T. Kishi, T. Takahashi, and T. Okamoto, Coenzyme Q Redox Cycle as an Endogenous Anioxidant. Carotenoids: W. Stahl and H. Sies, Carotenoids: Occurrence, Biochemical Activities, and Bioavailability. F. Khachik, J.S. Bertram, M.-T. Huang, J.W. Fahey, and P. Talalay, Dietary Carotenoids and Their Metabolites as Potentially Useful Chemoprotective Agents Against Cancer. H. Nishino, Cancer Prevention by Natural Carotenoids. Flavonoids: C. Rice-Evans, Screening of Phenolics and Favonoids for Antioxidant Activity. J. Terao, Dietary Flavonoids as Plasma Antioxid

Details

No. of pages:
511
Language:
English
Copyright:
© 1999
Published:
Imprint:
Academic Press
eBook ISBN:
9780080527284
Print ISBN:
9780125435901
Print ISBN:
9780123992499

About the editors

Lester Packer

Lester Packer received a PhD in Microbiology and Biochemistry in 1956 from Yale University. In 1961, he joined the University of California at Berkeley serving as Professor of Cell and Molecular Biology until 2000, and then was appointed Adjunct Professor, Pharmacology and Pharmaceutical Sciences, School of Pharmacy at the University of Southern California. Dr Packer received numerous distinctions including three honorary doctoral degrees, several distinguished Professor appointments. He was awarded Chevalier de l’Ordre National du Merite (Knight of the French National Order of Merit) and later promoted to the rank of Officier. He served as President of the Society for Free Radical Research International (SFRRI), founder and Honorary President of the Oxygen Club of California. He has edited numerous books and published research; some of the most cited articles have become classics in the field of free radical biology: Dr Packer is a member of many professional societies and editorial boards. His research elucidated - the Antioxidant Network concept. Exogenous lipoic acid was discovered to be one of the most potent natural antioxidants and placed as the ultimate reductant or in the pecking order of the “Antioxidant Network” regenerating vitamins C and E and stimulating glutathione synthesis, thereby improving the overall cellular antioxidant defense. The Antioxidant Network is a concept addressing the cell’s redox status. He established a world-wide network of research programs by supporting and co-organizing conferences on free radical research and redox biology in Asia, Europe, and America.

Affiliations and Expertise

Department of Molecular Pharmacology and Toxicology, School of Pharmaceutical Sciences, University of Southern California, USA

Midori Hiramatsu

Affiliations and Expertise

Institute for Life Support Technology, Yamagata Technopolis Foundation, Japan

Toshikazu Yoshikawa

Affiliations and Expertise

Kyoto Prefectural University of Medicine, Japan