Antimicrobial Peptides

Antimicrobial Peptides

1st Edition - March 1, 2022
This is the Latest Edition
  • Editor: Leslie Hicks
  • Hardcover ISBN: 9780323901581

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Description

Antimicrobial Peptides, Volume 663 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on Unifying the classification of antimicrobial peptides in the Antimicrobial Peptide Database, Optimizing peptide library creation for PepSAVI-MS (RP libraries, etc.), Discovery of novel Antimicrobial peptides using BioProspecting, Screening for cysteine-stabilized scaffolds for developing protelytic-resistant AMPs, Exploring synergy and its role in antimicrobial peptide biology, Colorimetric assays for the rapid and high-throughput screening of antimicrobial peptide activity against diverse bacterial pathogens, and much more. Other chapters cover Liquid chromatography-mass spectrometry-based analysis of naturally occurring neuropeptide diastereomers, Multiplexed Quantitative Neuropeptidomics via DiLeu Isobaric Tagging, In vitro evaluation of antibiotic resistance via proteomics, Molecular networking-based strategies in mass spectrometry, Development of Macrocyclic antimicrobial peptides and peptoids, and a host of other timely topics.

Key Features

  • Provides the authority and expertise of leading contributors from an international board of authors
  • Presents the latest release in Methods in Enzymology serials
  • Updated release includes the latest information on Antimicrobial Peptides

Readership

Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists

Table of Contents

  • 1. Unifying the classification of antimicrobial peptides in the Antimicrobial Peptide Database
    Guangshun Wang
    2. Optimizing peptide library creation for PepSAVI-MS (RP libraries, etc)
    Leslie M. Hicks
    3. Discovery of novel Antimicrobial peptides using BioProspecting
    Monique van Hoek and Barney Bishop
    4. Screening for cysteine-stabilized scaffolds for developing protelytic-resistant AMPs
    Octávio Luiz Franco
    5. Exploring synergy and its role in antimicrobial peptide biology
    Alfredo Angeles-Boza
    6. Colorimetric assays for the rapid and high-throughput screening of antimicrobial peptide activity against diverse bacterial pathogens
    Lindsey Shaw and Jessie Allen
    7. Prioritization of antimicrobial peptide candidate utilizing the PepSAVI-MS pipeline (predictions, mass shift analysis, fingerprinting)
    Leslie M. Hicks
    8. Combined Thermal and Carboxypeptidase Y Stability Assays for Proving the Threaded Fold of Lasso Peptides
    Julian David Hegemann
    9. Liquid chromatography-mass spectrometry-based analysis of naturally occurring neuropeptide diastereomers
    James W. Checco
    10. Multiplexed Quantitative Neuropeptidomics via DiLeu Isobaric Tagging
    Lingjun Li
    11. In vitro evaluation of antibiotic resistance via proteomics
    Leslie M. Hicks
    12. Molecular networking-based strategies in mass spectrometry
    Neha Garg
    13. Development of Macrocyclic antimicrobial peptides and peptoids
    Havard Jenssen
    14. Synthetic approaches for peptide antibiotic design
    Cesar de la Fuente
    15. Fast Solid-Phase synthesis of peptoids for antimicrobial studies
    Biljana Mojsoska
    16. Molecular networking in infectious disease models
    Laura-Isobel McCall
    17. Building Predictive Libraries of Antimicrobial Peptides with Artificial Intelligence / Machine Learning
    Annalisa Pawlosky

Product details

  • No. of pages: 412
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: March 1, 2022
  • Imprint: Academic Press
  • Hardcover ISBN: 9780323901581
  • About the Serial Volume Editor

    Leslie Hicks

    Dr. Hicks received her B.S. in Chemistry at Marshall University, summa cum laude, and Ph.D. in Analytical Chemistry at the University of Illinois, Urbana-Champaign where she was the recipient of an NSF Graduate Research Fellowship. She was an Assistant Member and Principal Investigator at the Donald Danforth Plant Science Center and an adjunct professor in the Department of Biology at Washington University in St. Louis prior to assuming her current role as a professor in the Department of Chemistry at UNC.

    Affiliations and Expertise

    Associate Professor, Department of Chemistry, University of North Carolina at Chapel Hill, USA