Antidotes to Toxins and Drugs

Antidotes to Toxins and Drugs

From Natural Sources to Drug Discovery in Toxicology

1st Edition - December 1, 2022

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  • Editors: Mihnea-Alexandru Găman, Chukwuebuka Egbuna
  • Paperback ISBN: 9780128244722

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Description

Antidotes to Toxins and Drugs: From Natural Sources to Drug Discovery in Toxicology presents recent advances in the discovery of natural antidotes to toxins, drug intoxications and overdoses in pharmacology, drug discovery and toxicology. The text provides detailed information about toxins and their natural antidotes, along with the identification and screening of antidotes for drug intoxications and overdoses. Written by a global team of experts, it describes the potential uses of natural products in toxicology and their applications in medicine and in the pharmaceutical sciences. This book will be a key resource for drug developers, medicinal chemists and toxicologists, among others.Sections shine a particular focus on mechanisms of action, various principles in pharmacokinetics and pharmacodynamics terms, and possible sources and synthesis techniques for these phytochemicals.

Key Features

  • Details recent advances in the discovery of natural antidotes from medicinal plants and phytochemicals
  • Includes advances in the discovery of antidotes to drug intoxications and overdoses
  • Describes modern screening assays for toxins and drug intoxications
  • Features information on recent advances in toxicology

Readership

Researchers in organic and medicinal chemistry including drug developers, medicinal chemists, toxicologists, analytical chemists, Researchers in pharmaceutical and biotech industries

Table of Contents

  • 1. Toxins of Natural Products
    2. Antidotes to Bacterial Toxins/Toxic Substances from Bacteria

    In Vivo Bacterial Toxins, Toxic Shock Syndrome, Bacterial Toxins Produced Outside the Body
    3. Antidotes to Mycotoxins, Aflatoxins, Other Mycotoxins, Mushroom Toxins
    4. Antidotes to Toxins from Protozoa
    5. Antidotes to Toxic Substances from Plants

    Nerve Toxins from Plants e.g. Pyrethrins and Pyrethroids; Internal Organ Plant Toxins; Eye and Skin Irritants; Allergens; Mineral Accumulators; Toxic Algae
    6. Antidotes to Insect Toxins, Bee Venom; Wasp and Hornet Venoms; Toxicities of Insect Venoms
    7. Antidotes to Spider Toxins

    Brown Recluse Spiders; Widow Spiders; Other Spiders
    8. Antidotes to Reptile Toxins

    Chemical Composition of Snake Venoms; Toxic Effects of Snake Venom
    9. Antidotes to Nonreptile Animal Toxins
    10. Antidotes to Drug Intoxications or Drug Overdoses

Product details

  • No. of pages: 420
  • Language: English
  • Copyright: © Elsevier 2023
  • Published: December 1, 2022
  • Imprint: Elsevier
  • Paperback ISBN: 9780128244722

About the Editors

Mihnea-Alexandru Găman

Mihnea-Alexandru Găman received his M.D. at the Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania. Dr. Găman is currently specialising in Clinical Haematology at the Department of Haematology, Centre of Haematology and Bone Marrow Transplantation, Fundeni Clinical Institute, Bucharest, Romania. Dr. Găman conducts research in the fields of Haematology, Oncology, Molecular and Cell Biology, Internal Medicine, Pharmacology, Pharmacy and Pharmaceutical Sciences, and has published over 30 papers in international and national impact factor journals, as well as served as editor and author for international and national books/book chapters. Dr. Găman has also been appointed as Scientific Editor for the International Journal of Medical Students (IJMS) and has served as peer-reviewer for over 50 international and national journals. Dr. Găman has received training in his home country, Romania, as well as Germany, Italy, Poland and the United States of America as part of several research teams.

Affiliations and Expertise

Specialist, Clinical Haemotology, Department of Haemotology, Centre of Haemotology and Bone Marrow Transplantation, Fundeni Clinical Institute, Bucharest, Romania

Chukwuebuka Egbuna

Chukwuebuka Egbuna is a chartered chemist and academic researcher. He is a member of the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), and the Royal Society of Chemistry (RSC) (United Kingdom). Egbuna is the founder and editor of the Elsevier book series on Drug Discovery Update. The series includes books, monographs and edited collections from all areas of drug discovery including emerging therapeutic claims for the treatment of diseases. He has been engaged in a number of roles at New Divine Favor Pharmaceutical Industry Limited, Akuzor Nkpor, Anambra State, Nigeria, and Chukwuemeka Odumegwu Ojukwu University (COOU) in Nigeria. Egbuna has published research articles in many international journals of repute and is ranked among the top 500 Nigerian scientists in SciVal/SCOPUS. He has edited over 20 books with Elsevier, Springer, Wiley and Taylor & Francis. His most recent book is his 3 volume book on Coronavirus Drug Discovery published by Elsevier. Egbuna is the founder and the publishing director of IPS Intelligentsia Publishing Services. He is a reviewer and editorial board member of various journals. His primary research interests cut across biochemistry, phytochemistry, pharmacology, nutrition and toxicology, food and medicinal chemistry, and analytical biochemistry.

Affiliations and Expertise

chartered chemist and academic researcher. He is a member of the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), and the Royal Society of Chemistry (RSC) (United Kingdom).

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