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Antibodies, Antigens, and Molecular Mimicry - 1st Edition - ISBN: 9780121820794, 9780080882956

Antibodies, Antigens, and Molecular Mimicry, Volume 178

1st Edition

Editors in Chief: John Abelson Melvin Simon
Serial Volume Editor: John Langone
eBook ISBN: 9780080882956
Imprint: Academic Press
Published Date: 28th November 1989
Page Count: 835


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Table of Contents

Idiotypes, Anti-idiotypes, and Molecular Mimicry: Concepts and Methods: H. Kadohler, S. Kaveri, T. Kieber-Emmons, W.J.W. Morrow, S. Maduller, and S. Raychaudhuri, Idiotypic Networks and the Nature of Molecular Mimicry: An Overview. M.R. Schick and R.C. Kennedy, Production and Characterization of Anti-idiotypic Antibody Reagents. P.H. Kussie, G. Albright, and D.S. Linthicum, Production and Characterization of Monoclonal Idiotypes and Anti-idiotypes for Small Ligands. J.E. Blalock, J.N. Whitaker, E.N. Benveniste, and K.L. Bost, Use of Peptides Encoded by Complimentary RNA for Generating Anti-idiotypic Antibodies of Predefined Specificity. F. Perosa, T. Kageshita, R. Ono, and S. Ferrone, Serological Methods to Detect Anti-idiotypic Antibodies. P.H.Kussie, M.A. Sherman, D. Marchetti, and D.S. Linthicum, Molecular Analysis of Monoclonal Idiotypes and Anti-idiotypes. F.J. Stevens, Size-Exclusion High Performance Liquid Chromatography in Analysis of Protein and Peptide Epitopes. K.H.Roux, Immunoelectron Microscopy of Idiotype-Anti-idiotype Complexes. C. Petit, M.E. Sauron, M. Gilbert, and J. Thabeze, Use of Immunoblotting to Detect Idiotypic Determinants on Monoclonal Antibodies. M.G. Jacquemin and J.-M.R. Saint-Remy, Idiotypes Carried by Antiallergen Antibodies. D.S. Ludwig and G.K. Schoolnik, Structure-Function Analysis of Protein Active Sites with Anti-idiotypic Antibody. M.J. Nelles, Competitive Idiotype-Anti-idiotype Enzyme Immunoassay for Adenosine Deaminase Binding Protein. Anti-idiotype Molecular Mimicry and Receptors: A.D. Strosberg, Interaction of Anti-idiotypic Antibodies with Membrane Receptors: Practical Considerations. N.R. Farid, Anti-idiotypic Antibodies as Probes of Hormone Receptor Structure and Function. K.M. Knigge, D.T. Piekut, L.G. Abood, S.A. Joseph, G.J. Michael, L. Xin, and D.J. Berlove, Immunocytochemistry of Receptors Using Anti-idiotypic Antibodies. J.A. Glasel, Production and Properties of Antimorphine Anti-idiotypic Antibodies and their Antiopiate Receptor Activity. C. Gramsch, R. Schulz, S. Kosin, A.H.S. Hassan, and A. Herz, Production and Characterization of Anti-idiotypic Antiopioid Receptor Antibodies. A.D. Strosberg, Anti-idiotypic Antibodies That Interact with ~gb-Adrenergic Catecholamine Receptor. J.-Y. Couraud, S. Maillet, J. Grassi, Y. Frobert, and P. Pradelles, Characterization and Properties of Antisubstance P Anti-idiotypic Antibodies. I.R. Cohen, D. Elias, M. Rapoport, and Y. Shechter, Production and Properties of Anti-idiotypic Antibodies That Recognize Insulin Receptor. M.B.H. Youdim, R.J. Barkey, T. Amit, and J. Guy, Anti-idiotypic Antibodies as Probes of Prolactin Receptor. W.V. Williams, D.B. Weiner, and M.I. Greene, Development and Use of Antireceptor Antibodies to Study Interaction of Mammalian Reovirus Type 3 with Its Cell Surface Receptor. Anti-idiotype Vaccines and Immunotoxins: G.T. Stevenson, Use of Anti-idiotypic Antibodies to Treat Lymphoid Tumors. S. Bridges, D.L. Longo, and R.J. Youle, Preparation and Use of Anti-idiotypic Antibodies Armed with Holotoxins or Hemitoxins in Treatment of B-Cell Neoplasms. E. Hurwitz and J. Haimovich, Use of Anti-idiotypic Antibody-Drug Conjugates to Treat Experimental Murine B-Cell Tumors. G.F. Rimmelzwaan, E.J. Bunschoten, F.G.C.M. UytdeHaag, and A.D.M.E. Osterhaus, Monoclonal Anti-idiotypic Antibody Vaccines against Poliovirus, Canine Parvovirus, and Rabies Virus. J-M. Grzych, F. Roussel-Velge, and A. Capron, Use of Anti-idiotype Antibodies in Approaches to Immunoprophylaxis of Schistosomiasis. M. Colombatti, L. Dell'Arciprete, R. Rappuoli, and G. Tridente, Selective Immunotoxins Prepared with Mutant Diphtheria Toxins Coupled to Monoclonal Antibodies. T. Sasaki, Y. Koide, and K. Yoshigaga, Immune Suppression on Anti-DNA Antibody Production Using Anti-idiotypic Antibody-Neocarzinostatin Conjugates. M.C. Souroujon and S. Fuchs, Anti-idiotypic Antibodies in the Study and Treatment of Experimental Autoimmune Myasthenia Gravis. K.A. Krolick, Inhibition of Autoimmune Reactivity against Acetylcholine Receptor with Idiotype-Specific Immunotoxins. Engineered Antibodies: S.-U. Shin and S.L. Morrison, Production and Properties of Chimeric Antibody Molecules. M. Better and A.H. Horwitz, Expression of Engineered Antibodies and Antibody Fragments in Microorganisms. A. Pladuckthun and A. Skerra, Expression of Functional Antibody Fv and Fab Fragments in Escherichia coli. T.W.Love, M.S. Runge, E. Haber, and T. Quertermous, Recombinant Antibodies Possessing Novel Effector Functions. Catalytic Antibodies or Abzymes: A. Tramontano and D. Schloeder, Production of Antibodies That Mimic Enzyme Catalytic Activity. S.J. Pollack, G.R. Nakayama, and P.G. Schultz, Design of Catalytic Antibodies. Epitope Design and Applications: T.P. Hopp, Use of Hydrophilicity Plotting Procedures to Identify Protein Antigenic Segments and Other Interaction Sites. V. Krchajnaaak, O. Mach, and A. Mal~aay, Computer Prediction of B-Cell Determinants from Protein Amino Acid Sequences Based on Incidence of ~gb-Turns. J.L. Cornette, H. Margalit, C. DeLisi, and J.A. Berzofsky, Identification of T-Cell Epitopes and Use in Construction of Synthetic Vaccines. D.R. Milich and G.B. Thornton, Use of Synthetic T-Cell Epitopes as Immunogens to Induce Antibodies to Hepatitis B Components. M.J. Francis and B.E. Clarke, Peptide Vaccines Based on Enhanced Immunogenicity of Peptide Epitopes Presented with T-Cell Determinants of Hepatitis B Core Protein. J. McCray and G. Werner, Production and Properties of Site-Specific Antibodies to Synthetic Peptide Antigens Related to Potential Cell Surface Receptor Sites for Rhinovirus. J.W. Gnann, Jr., L.L. Smith, and M.B.A. Oldstone, Custom-Designed Synthetic Peptide Immunoassays for Distinguishing HIV Type 1 and Type 2 Infections. H. Meiri, M. Sammar, and A. Schwartz, Production and Use of Synthetic Peptide Antibodies to Map Region Associated with Sodium Channel Inactivation. D.N. Posnett and J.P.Tam, Multiple Antigenic Peptide Method for Producing Antipeptide Site-Specific Antibodies.


The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.


Biochemists, immunologists, virologists, oncologists, analytical chemists, clinical chemists, pharmacologists, cell and molecular biologists, microbiologists, and graduate students in biochemistry, biology, and microbiology.


No. of pages:
© Academic Press 1989
28th November 1989
Academic Press
eBook ISBN:


@from:Praise for the Volume @qu:"John Langone has compiled an important current volume with four sections: idiotypes, anti-idiotypes, and molecular mimicry; engineered antibodies; catalytic antibodies; and peptide epitope design and applications... This book should be useful for investigators who have some experience with immunological methods but seek a wide range of examples, protocols, priciples, and references in one source." @source:--ANALYTICAL BIOCHEMISTRY @from:Praise for the Series @qu:"The Methods in Enzymology series represents the gold-standard." @source:--NEUROSCIENCE @qu:"Incomparably useful." @source:--ANALYTICAL BIOCHEMISTRY @qu:"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page." @source:--BIO/TECHNOLOGY @qu:"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection." @source:--CHEMISTRY IN INDUSTRY @qu:"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced." @source:--AMERICAN SOCIETY OF MICROBIOLOGY NEWS @qu:"If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work." @source:--ENZYMOLOGIA @qu:"A series that has established itself as a definitive reference for biochemists." @source:--JOURNAL OF CHROMATOGRAPHY

About the Editors in Chief

John Abelson

Affiliations and Expertise

California Institute of Technology, Division of Biology, Pasadena, U.S.A.

Melvin Simon

Affiliations and Expertise

The Salk Institute, La Jolla, CA, USA

About the Serial Volume Editor

John Langone

Affiliations and Expertise

Center for Devices and Radiological Health, Food and Drug Administration, Rockville, Maryland, U.S.A.