Annual Reports in Medicinal Chemistry, Volume 42

1st Edition

Paperback ISBN: 9780123739124
eBook ISBN: 9780080554877
Imprint: Academic Press
Published Date: 20th November 2007
Page Count: 646
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Table of Contents

I. Central Nervous System Diseases -Potential CNS Applications for Phosphodiesterase Enzyme Inhibitors (N. J. Brandon and D. P. Rotella) -Recent Developments in Monoamine Reuptake Inhibitors (S. Liu and B. F. Molino) Secretase Inhibitors and Modulators for the Treatment of Alzheimer's Disease (R. E. Olson and L. R. Marcin) -Recent Advances in Drug Discovery of Histamine H3 Antagonists (R. L. Hudkins, R. Raddatz) -Recent Advances in the Treatment of Insomnia (A. Palomer, M. Princep and A. Guglietta) -Advances in Transient Receptor Potential (TRP) Modulators (A. Vasudevan, M. E. Kort) II. Cardiovascular and Metabolic Diseases -Case History: JANUVIA (Sitagliptin), a Selective Dipeptidyl Peptidase IV Inhibito for the Treatment of Type 2 Diabetes (A. E. Weber, N. Thornberry) -Cathepsin K Inhibitors (W. Cameron Black and M. David Percival) -New Nonpeptide-Binding GPCRs as Targets for Diabetes and the Metabolic Syndrome (M. C.T.Fyfe, H. A.Overton, M. J.Procter, C. Reynet & J. R. White) -Novel Selective Estrogen Receptor Modulators (SERMS) (J. A. Dodge and T. I. Richardson) -Lipid-metabolizing enzymes as targets for dyslipidemia and insulin resistance (V. Yeh, A. S. Judd, and A. J. Souers) -Recent Trends in HDL Modulating Therapies (D. De and I. Khanna) III. Inflammation / Pulmonary / GastroIntestinal Diseases -Case History on Tegaserod (R. Giger, H. Mattes and H.-J. Pfannkuche) -Advances in the Discovery of CC Chemokine Receptor-2 Atagonists (P. Carter, R. Cherney, I. K.Mangion) -Semicarbazide Sensitive Amine Oxidase and Vascular Adhesion Protein-1: One Protein Being Validated as a Therapeutic Target for Inflammatory Diseases (I. McDonald, J. Foot, P. Yin, E. Flening, E. M. van Dam) -Sphingosine 1-Phospate T

Description

Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.

Key Features

  • Critical reviews of the previous year’s literature in many topics of interest to medicinal chemists
  • Highlights major developments in medicinal chemistry
  • Includes a comprehensive set of cumulative indexes to easily locate topics in all published volumes

Readership

For medicinal, pharmaceutical and organic chemists


Details

No. of pages:
646
Language:
English
Copyright:
© Academic Press 2007
Published:
Imprint:
Academic Press
eBook ISBN:
9780080554877
Paperback ISBN:
9780123739124