Annual Reports in Medicinal Chemistry

Annual Reports in Medicinal Chemistry

1st Edition - August 30, 1999

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  • Editor-in-Chief: Annette Doherty
  • eBook ISBN: 9780080583785

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Annual Reports in Medicinal Chemistry continues to strive to provide timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences which are expected to provide the basis for entirely new future therapies.Volume 34 retains the familiar format of previous volumes, this year with 33 chapters. Sections I-IV are disease-oriented and generally report on specific medicinal agents with updates from Volume 33 on antithrombotics, neurokinin receptor antagonists, anticoagualants, and new antibacterials. As in past volumes, annual updates have been limited to only the most active areas of research in favor of specifically focused and mechanistically oriented chapters, where the objective is to provide the reader with the most important new results in a particular field.Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design as well as the critical interfaces among these disciplines. This volume concludes with To Market, To Market--a chapter on NCE and NBE introductions worldwide in 1998, a chapter on pharmagenomics, and finally one on malaria as a third world disease in need of a first world drug development.


Medicinal, pharmaceutical, and organic chemists.

Table of Contents

  • Section Editor: D.W. Robertson, Central Nervous System Diseases. Section Editor: W.J. Greenlee, Cardiovascular and Pulmonary Diseases. Section Editor: J.J. Plattner, Cancer and Infectious Diseases. Section Editor: W.K. Hagmann, Immunology, Endocrinology, and Metabolic Diseases. Section Editor: W.W. Wong, Topics in Biology. G.L. Trainor, Topics in Drug Design and Discovery. Section Editor: A.M. Doherty, Trends and Perspectives.

    D.A. Evrard and B.L. Harrison, Recent Approaches to Novel Antidepressant Therapy. J.R. McCarthy, S.C. Heinrichs, and D.E. Grigoriadis, Recent Progress in Corticotropin-Releasing Factor Receptor Agents. C.E. Augelli-Szafran, L.C. Walker, and H. LeVine III, ß-Amyloid as a Target for Alzheimer's Disease Therapy. A.W Stamford and E.M. Parker, Recent Advances in the Development of Neuropeptide Y Receptor Antagonists. K.S. Takaki and J.R. Epperson, Pharmacological Interventions in the Sleep Process. C. Swain and N.M.J. Rupniak, Progress in the Development of Neurokinin Antagonists.

Product details

  • No. of pages: 413
  • Language: English
  • Copyright: © Academic Press 1999
  • Published: August 30, 1999
  • Imprint: Academic Press
  • eBook ISBN: 9780080583785

About the Editor in Chief

Annette Doherty

Affiliations and Expertise

Pfizer Global R&D, Sandwich Laboratories, United Kingdom

About the Serial Editors

William Greenlee

William Hagmann

Affiliations and Expertise

Parke-Davis Pharmaceutical Research

Jacob Plattner

David Robertson

Affiliations and Expertise

Clinical Research Center, Vanderbilt University, Nashville, Tennessee, U.S.A.

George Trainor

Winnie Wong

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