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Annual Reports in Medicinal Chemistry - 1st Edition - ISBN: 9780120405312, 9780080583754

Annual Reports in Medicinal Chemistry, Volume 31

1st Edition

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Editor in Chief: James Bristol
Serial Volume Editors: David Robertson Annette Doherty Jacob Plattner William Hagmann Winnie Wong George Trainor
eBook ISBN: 9780080583754
Imprint: Academic Press
Published Date: 30th September 1996
Page Count: 413
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Table of Contents

D.W. Robertson, Central Nervous System Diseases: P.A. Hipskind and D.R. Gehlert, Neuropeptide Y: At the Dawn of Subtype Selective Antagonists. R.C. Miranda and F. Sohrabji, Gonadal Steroid Receptors: Possible Roles in the Etiology and Therapy of Cognitive and Neurological Disorders. M. Williams and S.S. Bhagwat, P2 Purinoceptors: A Family of Novel Therapeutic Targets. D.J. Madge and A.M. Batchelor, The Metabotropic Glutamate Receptors.D.C. Rees and D.R. Hill, Drugs in Anesthetic Practice. A.M. Doherty, Cardiovascular and Pulmonary Diseases: J.J. Edmunds, S.T. Rapundalo, and M.A. Siddiqui, Thrombin and Factor Xa Inhibition. M. Czarniecki, H.-S. Ahn, and E.J. Sybertz, Inhibitors of Types I and V Phosphodiesterase: Elevation of cGMP as a Therapeutic Strategy. J.A. Stafford and P.L. Feldman, Chronic Pulmonary Inflammation and Other Therapeutic Applications of PDE IV Inhibitors. M.A. Lago, J.I. Luengo,C.E. Peishoff, and J.D. Elliott, Endothelin Antagonists. J. Samanen, GPIIb/IIIa Antagonists. P. Charlton and M. Sumner, Atherothrombogenesis. C.J. Swain and R.J. Hargreaves, Neurokinin Receptor Antagonists. J.J. Plattner, Cancer and Infectious Diseases: B.H. Jaynes, J.P. Dirlam, and S.J. Hecker, Antibacterial Agents. R.D.G. Cooper and R.C. Thompson, Semisynthetic Glycopeptide Antibiotics. M.C. Murray and M.E. Perkins, Chemotherapy of Malaria. D.W. Fry, Recent Advances in Tyrosine Kinase Inhibitors. W.R. Baker, T.M. Arain, R. Shawar, C.K. Stover, and L.A. Mitscher, Recent Advances in the Chemistry and Biology of Antimycobacterial Agents. S. Ayral-Kaloustian and J.S. Skotnicki, Ras Farnesyltransferase Inhibitors. W.K. Hagmann, Immunology, Endocrinology, and Metabolic Diseases: T.A. Grese and J.A. Dodge, Estrogen Receptor Modulators: Effects in Non-Traditional Target Tissues. V.W. Engleman, M.S. Kellogg, and T.E. Rogers, Cell Adhesion Integrins as Pharmaceutical Targets. D.R. Gehlert, D.J. Goldstein, and P.A. Hipskind, Treating Obesity in the 21st Century. P. Da Silva Jardine and D. Thompson, Anti-Osteoporosis Agents. J.E. Macdonald, Nitric Oxide Synthase Inhibitors. W.K. Hagmann, J.W. Becker, and M.W. Lark, Inhibition of Matrix Metalloproteinases. W.W. Wong, Topics in Biology: G. Draetta and M. Pagano, Cell Cycle Control and Cancer. D.K. Miller, Regulation of Apoptosis by Members of the ICE Family and the BcI2 Family. P. Lamb, H.M. Seidel, R.B. Stein, and J. Rosen, The Role of JAKs and STATs in Transcriptional Regulation by Cytokines. J. Adams and R. Stein, Novel Inhibitors of the Proteasome and Their Therapeutic Use in Inflammation. B. Stein and D. Anderson, The MAP Kinase Family: New MAPs for Signal Transduction Pathways and Novel Targets for Drug Discovery. G.L. Trainor, Topics in Drug Design and Discovery: S.J. Archer, P.J. Domaille, and E.D. Laue, New NMR Methods for Structural Studies of Proteins to Aid in Drug Design. I.C. Choong and J.A. Ellman, Solid-Phase Synthesis: Applications to Combinatorial Libraries. J.A. Loo, D.E. DeJohn, R.R.O. Loo, and P.C. Andrews, Application of Mass Spectrometry for Characterizing and Identifying Ligands from Combinatorial Libraries. R.E. Olson and D.D. Christ, Plasma Protein Binding of Drugs. J.A. Bristol, Trends and Perspectives: X.-M. Cheng, To Market, ToMarket--1995. A. Tulinsky, The Protein Structure Project, 1950-1959: First Concerted Effort of a Protein Structure Determination in the U.S. Compound Name, Code Number, and Subject Index, Volume 31. Cumulative Chapter Titles Keyword Index, Volumes 1-31. Cumulative NCE Introduction Index, 1983-1995. Cumulative NCE Introduction Index, 1983-1995, By Indication.


Advances in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.


Medicinal, pharmaceutical, and organic chemists.


No. of pages:
© Academic Press 1996
30th September 1996
Academic Press
eBook ISBN:


@qu:"This series is one of the very few annual publications which justify the title of an absolute must for the pharmacologist, chemist, or physician who is interested in the chemistry of drug development." @source:--ENZYMOLOGIA @qu:"This book is strongly recommended for researchers, teachers, students, administrators--in short, anyone whose interests impinge on medicinal chemistry. In view of the work's documented reference value, it is a must for inclusion in the scientist's personal library." @source:--JOURNAL OF MEDICINAL CHEMISTRY @qu:"All topics are covered in sufficient depth, with extensive references, to allow either the specialist or the novice to be informed of the latest developments in a particular area of medicinal chemistry." @source:--NORMAN GILMAN, Hoffmann-La Roche, Inc., in the JOURNAL OF PHARMACEUTICAL SCIENCES

Ratings and Reviews

About the Editor in Chief

James Bristol

Affiliations and Expertise

Parke-Davis Pharmaceutical Research

About the Serial Volume Editors

David Robertson

Affiliations and Expertise

Clinical Research Center, Vanderbilt University, Nashville, Tennessee, U.S.A.

Annette Doherty

Affiliations and Expertise

Pfizer Global R&D, Sandwich Laboratories, United Kingdom

Jacob Plattner

William Hagmann

Affiliations and Expertise

Parke-Davis Pharmaceutical Research

Winnie Wong

George Trainor