Annual Reports in Medicinal Chemistry
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Praise for the Series:"This series is one of the very few annual publications which justify the title of an absolute must for the pharmacologist, chemist, or physician who is interested in the chemistry of drug development."--Enzymologia"This book is strongly recommended for researchers, teachers, students, administrators - in short, anyone whose interests impinge on medicinal chemistry. In view of the work's documented reference value, it is a must for inlusion in the scientist's personal library."--Journal of Medicinal Chemistry"All topics are covered in sufficient depth, with extensive references, to allow either the specialist or the novice to be informed of the latest developments in a particular area of medicinal chemistry."--Norman Gilman, Hoffmann-La Roche, Inc, in the JOURNAL OF PHARMACEUTICAL SCIENCESAdvances in Medicinal Chemistry continues to provide timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.
Readership
Medicinal, pharmaceutical, and organic chemists.
Table of Contents
- Central Nervous System Diseases: K. Rasmussen and V.P. Rocco, Recent Progress in Serotonin (5-HT)1A Receptor Modulators. A.B. Reitz, M.C. Jetter, K.D. Wild, and R.B. Raffa, Centrally Acting Analgesics. E.B. De Souza, T.W. Lovenberg, D.T. Chalmers, D.E. Grigoriadis, C.W. Liaw, D.P. Behan, and J.R. McCarthy, Heterogeneity of Corticotropin Releasing Factor Receptors: Multiple Targets for the Treatment of CNS and Inflammatory Disorders. K. Shiosakiand P. Puttfarcken, Emerging Opportunities in Neuroinflammatory Mechanisms of Neurodegeneration. I.A. McDonald, N. Cosford, and J.-M. Vernier, Nicotinic Acetylcholine Receptors: Molecular Biology, Chemistry and Pharmacology. J. Gilmore, C. Dell, D. Bowman, and D. Lodge, Neuronal Calcium Channels. Cardiovascular and Pulmonary Diseases: L.A. Denner and R.A.F. Dixon, Vascular Proliferative Disease. R.M. Scarborough, Anticoagulant Strategies Targeting Thrombin and Factor Xa. J.R. Empfield and K. Russell, Potassium Channel Openers. T.F. Walsh, Progress in the Development of Endothelin Receptor Antagonists. Cancer and Infectious Diseases: J.P. Dirlam, B.H. Jaynes, and M.R. Jefson, Antibacterial Agents. J.F. Barrett and R.E. Isaacson, Bacterial Virulence as a Potential Target for Therapeutic Intervention. A.M. Nadzan, Retinoids for the Treatment of Oncological Diseases. R.C. Goldman, Biological Response Modification by beta-D-Glucans. R.E. Boehme, A.D. Borthwick, and P.G. Wyatt, Antiviral Agents. L.L. Klein and S.K. Tanaka, Therapy of Helicobacter pylori Infections: Current Status and Future Directions. Immunology, Endocrinology and Metabolic Diseases: R.L. Dowand D.K. Kreutter, Recent Advancements in the Discovery and Development of Agents for the Treatment of Diabetes. M.T. Goulet, Gonadotropin Releasing Hormone Antagonists. D.B. Reitz and K. Seibert, Selective Cyclooxygenase Inhibitors. T.H. Claus and J.D. Bloom, beta<->3-Selective Adrenergic Receptor Agonists. Z.A. Nagy and D. Vidovic [accent], The T Cell--Antigen Presenting Cell Interaction as a Site for Immunosuppressive Interventions. K. Cooper and K. Neote, Chemokinesas Therapeutic Targets. Topics in Biology: L.E. Post, Gene Therapy: Progress, New Directions, and Issues. M.C. Botfield and J. Green, SH2 and SH3 Domains: Choreographers of Multiple Signaling Pathways. B. Beutler, Programmed CellDeath Mediated by Members of the TNF Receptor Family. M.L. Gishizky, Tyrosine Kinase Induced Mitogenesis: Breaking the Link with Cancer. Topics in Drug Design and Discovery: T.S. Scanlan, Catalytic Antibodies. R.S. McDowell and D.R. Artis, Structure-Based Design from Flexible Ligands. D.J. Matthews, Applications of Biosensor Technology in Drug Discovery. N. Usman and J.A. McSwiggen, Catalytic RNA (Ribozymes) as Drugs. Trends and Perspectives: X.-M. Cheng, ToMarket, To Market--1994. D. Stirling, Potential Use of Thalidomide in HIV/AIDS. C.R. Ganellin, L.A. Mitscher, and J.G. Topliss, Educating Medicinal Chemists. W.L. Thompson, Research Investments in a Managed Care, Cost-Containment, Oligopsony. Compound Name, Code Number, and Subject Index, Volume 30. Cumulative Chapter Titles Keyword Index, Volumes 1-30. Cumulative NCE Introduction Index, 1983-1994. Cumulative NCE Introduction Index, 1983-1994, By Indication.
Product details
- No. of pages: 387
- Language: English
- Copyright: © Academic Press 1995
- Published: September 6, 1995
- Imprint: Academic Press
- eBook ISBN: 9780080583747
About the Editor in Chief
James Bristol
Affiliations and Expertise
Parke-Davis Pharmaceutical Research
About the Serial Volume Editors
William Hagmann
Affiliations and Expertise
Parke-Davis Pharmaceutical Research
Michael Venuti
Affiliations and Expertise
Arris Pharmaceutical Corporation
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