Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expectedto provide the basis for entirely new future therapies.


Medicinal, pharmaceutical, and organic chemists.

Table of Contents

D.W. Robertson, Central Nervous System Diseases: T. Branchek and J.E. Audia, Recent Advances in Migraine Therapy. V. John, L.H. Latimer, J.S. Tung, and M.S. Dappen, Alzheimers Disease: Recent Advances on the Amyloid Hypothesis. D.R. Gehlert and M. Heiman, Obesity: Leptin--Neuropeptide Y Interactions in the Control Body Weight. C.D. Mahle, K.S. Takaki, and A.J. Watson, Melatonin Receptor Ligands and Their Potential Clinical Applications. P.J. Gilligan, P.R. Hartig, D.W. Robertson, and R. Zaczek, Corticotrophin-Releasing Hormone (CRH) Receptors and the Discovery of Selective Non-Peptide CRH Antagonists. S.G. Mills, Recent Advances in Neurokinin Receptor Antagonists. A.M.Doherty, Cardiovascular and Pulmonary Diseases: X-M. Cheng, K. Ahn, and S.J. Haleen, Endothelin Inhibitors. W.C. Ripka and G.P. Vlasuk, Antithrombotics/Serine Proteases. R.L. Bell, J.B. Summers, and R.R. Harris, Leukotriene Modulators as Therapeutic Agents in Asthma and Other Inflammatory Diseases. C.M. Hayward and M.J. Bamberger, Emerging Opportunities in the Treatment of Atherosclerosis. J.J. Plattner, Cancer and Infectious Diseases: J.M. Domagala and J.P.Sanchez, New Approaches and Agents to Overcome Bacterial Resistance. L. Katz, D.T. Chu, and K. Reich, Bacterial Genomics and the Search for Novel Antibiotics. A. Molla and W.E. Kohlbrenner, Resistance to Antiretroviral Drug Therapy. S.H. Krawczyk and N. Bischofberger, Non-HIV Antiviral Agents. P.A. Lartey and C.M. Moehle, Recent Advances in Antifungal Agents. D. Powell, J. Skotnicki, and J. Upeslacis, Angiogenesis Inhibitors. K.G. Coleman, J.P. Lyssikatos, and B.V. Yang, Chemical Inhibitors of Cyclin-Dependent Kinases. W.K. Hagmann, Immunology, Endocrinology, and Metabolic Diseases: <


No. of pages:
© 1997
Academic Press
Electronic ISBN:
Print ISBN:


@qu:This series is one of the very few annual publications which justify the title of an absolute must for the pharmacologist, chemist, or physician who is interested in the chemistry of drug development. @soource:--ENZYMOLOGIA @qu:This book is strongly recommended for researchers, teachers, students, administrators--in short, anyone whose interests impinge on medicinal chemistry. In view of the work's documented reference value, it is a must for inclusion in the scientist's personal library. @source:--JOURNAL OF MEDICINAL CHEMISTRY @qu:All topics are covered in sufficient depth, with extensive references, to allow either the specialist or the novice to be informed of the latest developments in a particular area of medicinal chemistry. @source:--NORMAN GILMAN, Hoffmann-La Roche, Inc., in the JOURNAL OF PHARMACEUTICAL SCIENCES