Annual Reports in Medicinal Chemistry - 1st Edition - ISBN: 9780120405329, 9780080583761

Annual Reports in Medicinal Chemistry, Volume 32

1st Edition

Editor-in-Chiefs: James Bristol
Serial Editors: David Robertson Annette Doherty William Hagmann Jacob Plattner Winnie Wong George Trainor
eBook ISBN: 9780080583761
Imprint: Academic Press
Published Date: 4th September 1997
Page Count: 378
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Table of Contents

D.W. Robertson, Central Nervous System Diseases:

T. Branchek and J.E. Audia, Recent Advances in Migraine Therapy. V. John, L.H. Latimer, J.S. Tung, and M.S. Dappen, Alzheimers Disease: Recent Advances on the Amyloid Hypothesis. D.R. Gehlert and M. Heiman, Obesity: Leptin--Neuropeptide Y Interactions in the Control Body Weight. C.D. Mahle, K.S. Takaki, and A.J. Watson, Melatonin Receptor Ligands and Their Potential Clinical Applications. P.J. Gilligan, P.R. Hartig, D.W. Robertson, and R. Zaczek, Corticotrophin-Releasing Hormone (CRH) Receptors and the Discovery of Selective Non-Peptide CRH Antagonists. S.G. Mills, Recent Advances in Neurokinin Receptor Antagonists. A.M.Doherty, Cardiovascular and Pulmonary Diseases: X-M. Cheng, K. Ahn, and S.J. Haleen, Endothelin Inhibitors. W.C. Ripka and G.P. Vlasuk, Antithrombotics/Serine Proteases. R.L. Bell, J.B. Summers, and R.R. Harris, Leukotriene Modulators as Therapeutic Agents in Asthma and Other Inflammatory Diseases. C.M. Hayward and M.J. Bamberger, Emerging Opportunities in the Treatment of Atherosclerosis. J.J. Plattner, Cancer and Infectious Diseases: J.M. Domagala and J.P.Sanchez, New Approaches and Agents to Overcome Bacterial Resistance. L. Katz, D.T. Chu, and K. Reich, Bacterial Genomics and the Search for Novel Antibiotics. A. Molla and W.E. Kohlbrenner, Resistance to Antiretroviral Drug Therapy. S.H. Krawczyk and N. Bischofberger, Non-HIV Antiviral Agents. P.A. Lartey and C.M. Moehle, Recent Advances in Antifungal Agents. D. Powell, J. Skotnicki, and J. Upeslacis, Angiogenesis Inhibitors. K.G. Coleman, J.P. Lyssikatos, and B.V. Yang, Chemical Inhibitors of Cyclin-Dependent Kinases. W.K. Hagmann, Immunology, Endocrinology, and Metabolic Diseases: J.C. Kath, D.C. Hanson, and K.G. Chandy, T Lymphocyte Potassium Channel Blockers. D.W. Combs, Male Contraception. S. Nagpal and R.A.S. Chandraratna, New Dermatological Agents for the Treatment of Psoriasis. P. Prasit and D. Riendeau, Selective Cyclooxygenase-2 Inhibitors. R.P. Nargund and L.H.T. Van der Ploeg, Growth Hormone Secretagogues. W.W. Wong, Topics in Biology, Novel Gene Switches for the Regulation of Gene Expression. R.A. Black, T.A. Bird, and K.M. Mohler, Agents that Block TNF-I Synthesis or Activity. D.W. Robertson, D.J. Manglesdorf, P.J. Willy, and R.A. Heyman, Nuclear Orphan Receptors: Scientific Progress and Therapeutic Opportunities. G.L. Trainor, Topics in Drug Design and Discovery: B.A. Beutal, Discovery and Identification of Lead Compounds from Combinational Mixtures. C. Fenselau,Electrospray Mass Spectrometric Characterization of Adducts Between Therapeutic Agents and Proteins. E.E. Sugg, Nonpeptide Agonists for Peptide Receptors: Lessons from Ligands. S.K. Wrigley and M.I. Chicarelli-Robinson, Natural Products Research and Pharmaceuticals in the 1990s. J.H. Lin and A.Y.H. Lu, Inhibition of Cytochrome P-450 and Implications in Drug Development. J.A. Bristol, Trends and Perspectives: P. Galatsis, To Market, To Market--1996. Compound Name, CodeNumber, and Subject Index, Volume 32. Cumulative Chapter Titles Keyword Index, Volumes 1-32. Cumulative NCE Introduction Index, 1983-1996. Cumulative NCE Introduction Index, 1983-1996, By Indication.


Description

Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expectedto provide the basis for entirely new future therapies.

Readership

Medicinal, pharmaceutical, and organic chemists.


Details

No. of pages:
378
Language:
English
Copyright:
© Academic Press 1997
Published:
Imprint:
Academic Press
eBook ISBN:
9780080583761

Reviews

@qu:This series is one of the very few annual publications which justify the title of an absolute must for the pharmacologist, chemist, or physician who is interested in the chemistry of drug development. @soource:--ENZYMOLOGIA @qu:This book is strongly recommended for researchers, teachers, students, administrators--in short, anyone whose interests impinge on medicinal chemistry. In view of the work's documented reference value, it is a must for inclusion in the scientist's personal library. @source:--JOURNAL OF MEDICINAL CHEMISTRY @qu:All topics are covered in sufficient depth, with extensive references, to allow either the specialist or the novice to be informed of the latest developments in a particular area of medicinal chemistry. @source:--NORMAN GILMAN, Hoffmann-La Roche, Inc., in the JOURNAL OF PHARMACEUTICAL SCIENCES


About the Editor-in-Chiefs

James Bristol Editor-in-Chief

Affiliations and Expertise

Parke-Davis Pharmaceutical Research

About the Serial Editors

David Robertson Serial Editor

Affiliations and Expertise

Clinical Research Center, Vanderbilt University, Nashville, Tennessee, U.S.A.

Annette Doherty Serial Editor

Affiliations and Expertise

Pfizer Global R&D, Sandwich Laboratories, United Kingdom

William Hagmann Serial Editor

Affiliations and Expertise

Parke-Davis Pharmaceutical Research

Jacob Plattner Serial Editor

Winnie Wong Serial Editor

George Trainor Serial Editor