Advances in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.


Medicinal, pharmaceutical, and organic chemists.

Table of Contents

D.W. Robertson, Central Nervous System Diseases: P.A. Hipskind and D.R. Gehlert, Neuropeptide Y: At the Dawn of Subtype Selective Antagonists. R.C. Miranda and F. Sohrabji, Gonadal Steroid Receptors: Possible Roles in the Etiology and Therapy of Cognitive and Neurological Disorders. M. Williams and S.S. Bhagwat, P2 Purinoceptors: A Family of Novel Therapeutic Targets. D.J. Madge and A.M. Batchelor, The Metabotropic Glutamate Receptors.D.C. Rees and D.R. Hill, Drugs in Anesthetic Practice. A.M. Doherty, Cardiovascular and Pulmonary Diseases: J.J. Edmunds, S.T. Rapundalo, and M.A. Siddiqui, Thrombin and Factor Xa Inhibition. M. Czarniecki, H.-S. Ahn, and E.J. Sybertz, Inhibitors of Types I and V Phosphodiesterase: Elevation of cGMP as a Therapeutic Strategy. J.A. Stafford and P.L. Feldman, Chronic Pulmonary Inflammation and Other Therapeutic Applications of PDE IV Inhibitors. M.A. Lago, J.I. Luengo,C.E. Peishoff, and J.D. Elliott, Endothelin Antagonists. J. Samanen, GPIIb/IIIa Antagonists. P. Charlton and M. Sumner, Atherothrombogenesis. C.J. Swain and R.J. Hargreaves, Neurokinin Receptor Antagonists. J.J. Plattner, Cancer and Infectious Diseases: B.H. Jaynes, J.P. Dirlam, and S.J. Hecker, Antibacterial Agents. R.D.G. Cooper and R.C. Thompson, Semisynthetic Glycopeptide Antibiotics. M.C. Murray and M.E. Perkins, Chemotherapy of Malaria. D.W. Fry, Recent Advances in Tyrosine Kinase Inhibitors. W.R. Baker, T.M. Arain, R. Shawar, C.K. Stover, and L.A. Mitscher, Recent Advances in the Chemistry and Biology of Antimycobacterial Agents. S. Ayral-Kaloustian and J.S. Skotnicki, Ras Farnesyltransferase Inhibitors. W.K. Hagmann, Immunology, Endocrinology, and Metabolic Diseases: T.A. Grese and J.A. Dodge, Es


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© 1996
Academic Press
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@qu:"This series is one of the very few annual publications which justify the title of an absolute must for the pharmacologist, chemist, or physician who is interested in the chemistry of drug development." @source:--ENZYMOLOGIA @qu:"This book is strongly recommended for researchers, teachers, students, administrators--in short, anyone whose interests impinge on medicinal chemistry. In view of the work's documented reference value, it is a must for inclusion in the scientist's personal library." @source:--JOURNAL OF MEDICINAL CHEMISTRY @qu:"All topics are covered in sufficient depth, with extensive references, to allow either the specialist or the novice to be informed of the latest developments in a particular area of medicinal chemistry." @source:--NORMAN GILMAN, Hoffmann-La Roche, Inc., in the JOURNAL OF PHARMACEUTICAL SCIENCES