Animal Virology V4

Animal Virology V4

1st Edition - January 1, 1976

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  • Editor: David Baltimore
  • eBook ISBN: 9780323142281

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Animal Virology consists of papers presented in a meeting which considered broad issues and advances in animal virology and tumor viruses. This book is divided into nine parts, representing the nine sessions of the meeting. Five of the nine sections deal particularly with viruses known to be oncogenic in animals, and one of these covers explicitly human oncornaviruses. The other four sections describe the processes common to all viruses: replication, protein synthesis, and persistence, wherein emphasis is given to negative strand viruses and plant viruses.

Table of Contents

  • Preface

    I. Messenger RNA Synthesis from DNA

    1. Synthesis of Viral RNA in Cells Infected by Avian Sarcoma Viruses

    2. Transcription of the Avian RNA Tumor Virus Glycoprotein Gene in Uninfected and Infected Cells

    3. Immunoprecipitation of Murine Leukemia Virus-Specific Polyribosomes: Identification of Virus-Specific Messenger RNA

    4. Isolation and Preliminary Characterization of SV40 Transcription Complex

    5. Expression of Adenovirus DNA during Production Infection

    6. Characterization of Viral, Single-Stranded DNA Sequences in Adenovirus Infected Cells

    II. Organization and Reverse Transcription of the RNA Tumor Virus Genome

    7. Structure of Rous Sarcoma Virus RNA: 1) Localization of N6-Methyladenosine; 2) The Sequence of 23 Nucleotides Following the 5' Capped Terminus m7GpppGmp

    8. Towards a Complete Genetic Map of Rous Sarcoma Virus

    9. A Partial Genetic Map of Rous Sarcoma Virus RNA: Location of Polymerase, Envelope and Transformation Markers

    10. The Initiation Sites of Rous Sarcoma Virus RNA-Directed DNA Synthesis In Vitro

    11. Transcription of Avian Sarcoma Virus RNA

    12. In Vitro Replication of RNA Tumor Viruses

    13. Pro viral DNA Synthesis I. Reverse Transcriptase, Primer tRNA, Nucleic Acid Binding Proteins

    14. Differences in the Glycoproteins of Avian Tumor Virus Recombinants: Evidence for Intragenic Crossing Over

    15. Transfection of Moloney MuLV DNA

    16. Defectiveness in the Bryan High Titer Strain of Rous Sarcoma Virus

    17. Host Restriction of Friend Leukemia Virus: Proteins and Messenger RNA

    18. Studies on the Mechanism of FV-1 Restriction: Properties of Determinants Specifying Viral Tropism

    III. Transformation and Differentiation

    19. Germ Line Integration and Leukemogenesis of Exogenous and Endogenous Murine Leukemia Viruses

    20. In Vitro Lymphoid Cell Transformation by Abelson Murine Leukemia Virus

    21. In Vitro Transformation of Specific Target Cells by Avian Leukemia Viruses

    22. Distribution and Function of Defined Regions of Avian Tumor Virus Genomesin Viruses and Uninfected cells

    23. Mechanisms of the H-2 Effect on Viral Leukemogenesis

    IV. Human Oncornaviruses

    24. Interspecies Transfer of RNA Tumor Virus Genes: Implications for the Search for "Human" Type C Viruses

    25. Some Evidence for Infectious Type-C Virus in Humans

    26. Spontaneous Type C Virus Expression in Human Embryonic Lung Cells (HEL-12): Comparison of Cloned and Mixed Cell Populations

    V. Negative Strand Viruses

    27. A Transcriptional Map of Vesicular Stomatitis Virus

    28. Evidence for the Synthesis of a 'Leader' RNA Segment followed by the Sequential Transcription of the Genes of Vesicular Stomatitis Virus

    29. Activation of Parainfluenza Viruses through Host-Dependent Cleavage of an Envelope Glycoprotein

    30. The Molecular Organization of Sendai Virus Nucleocapsids

    31. Supramolecular Organization of Proteins in Newcastle Disease Virus

    32. Influenza Viral RNA Transcripts Synthesized In Vivo and In Vitro

    33. The Structure of the RNA of Uukuniemi Virus, A Proposed Bunyavirus

    VI. Plant Viruses

    34. Structure and Replication of Plant Viroids

    35. Complementarity Between Potato Spindle Tuber Vitroid and Cellular DNA: Measurement by RNA-DNA Hybridization

    36. Translation and Structure of the RNAs of Brome Mosaic Virus

    37. Translation of Tobacco Mosaic Virus RNA

    38. Novel Sequencing Techniques Applied to the "tRNA-Like" 3'-Terminus of Turnip Yellow Mosaic Virus RNA

    VII. Herpes Viruses

    39. Genetics of Herpesvirus

    40. The DNA of Epstein-Barr Virus Fragments Produced by Restriction Enzymes: Homologous DNA and RNA in Lymphoblastoid Cells

    41. Expression and Regulation of Epstein-Barr Virus in Mammalian Cells

    VIII. Viral Protein Synthesis

    42. 5'-Terminal 7-Methylguanosine in Viral mRNAs and Its Role in Translation

    43. Synthesis of the Polymerase Polypeptides of Semliki Forest Virus

    44. Biosynthesis and Processing of Rauscher Leukemia Viral Precursor Polyp roteins

    45. Regulation of Protein Synthesis in EMC Virus Infected Cells

    IX. Mechanisms of Viral Persistance

    46. The Role of Major Histocompatibility Antigens in Cell-Mediated Immunity to Virus Infections

    47. Establishment and Detection of Animal DNA Proviruses in Cell Culture Systems

    48. Defective Interfering Virus Particles Attenuate Virus Lethality In Vivo and In Vitro

    49. Hepatitis B Virus: A Cause of Persistent Virus Infection in Man

    Author Index

    Subject Index

Product details

  • No. of pages: 838
  • Language: English
  • Copyright: © Academic Press 1976
  • Published: January 1, 1976
  • Imprint: Academic Press
  • eBook ISBN: 9780323142281

About the Editor

David Baltimore

Microbiologist, educator. Gairdner Foundation Annual Award, 1975; US Steel Award in Molecular Biology, 1974. Nobel Prize for Medicine, 1975.

Affiliations and Expertise

California Institute of Technology, Pasadena, U.S.A.

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