Animal Virology V4 - 1st Edition - ISBN: 9780120773503, 9780323142281

Animal Virology V4

1st Edition

Editors: David Baltimore
eBook ISBN: 9780323142281
Imprint: Academic Press
Published Date: 1st January 1976
Page Count: 838
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Animal Virology consists of papers presented in a meeting which considered broad issues and advances in animal virology and tumor viruses. This book is divided into nine parts, representing the nine sessions of the meeting. Five of the nine sections deal particularly with viruses known to be oncogenic in animals, and one of these covers explicitly human oncornaviruses. The other four sections describe the processes common to all viruses: replication, protein synthesis, and persistence, wherein emphasis is given to negative strand viruses and plant viruses.

Table of Contents


I. Messenger RNA Synthesis from DNA

1. Synthesis of Viral RNA in Cells Infected by Avian Sarcoma Viruses

2. Transcription of the Avian RNA Tumor Virus Glycoprotein Gene in Uninfected and Infected Cells

3. Immunoprecipitation of Murine Leukemia Virus-Specific Polyribosomes: Identification of Virus-Specific Messenger RNA

4. Isolation and Preliminary Characterization of SV40 Transcription Complex

5. Expression of Adenovirus DNA during Production Infection

6. Characterization of Viral, Single-Stranded DNA Sequences in Adenovirus Infected Cells

II. Organization and Reverse Transcription of the RNA Tumor Virus Genome

7. Structure of Rous Sarcoma Virus RNA: 1) Localization of N6-Methyladenosine; 2) The Sequence of 23 Nucleotides Following the 5' Capped Terminus m7GpppGmp

8. Towards a Complete Genetic Map of Rous Sarcoma Virus

9. A Partial Genetic Map of Rous Sarcoma Virus RNA: Location of Polymerase, Envelope and Transformation Markers

10. The Initiation Sites of Rous Sarcoma Virus RNA-Directed DNA Synthesis In Vitro

11. Transcription of Avian Sarcoma Virus RNA

12. In Vitro Replication of RNA Tumor Viruses

13. Pro viral DNA Synthesis I. Reverse Transcriptase, Primer tRNA, Nucleic Acid Binding Proteins

14. Differences in the Glycoproteins of Avian Tumor Virus Recombinants: Evidence for Intragenic Crossing Over

15. Transfection of Moloney MuLV DNA

16. Defectiveness in the Bryan High Titer Strain of Rous Sarcoma Virus

17. Host Restriction of Friend Leukemia Virus: Proteins and Messenger RNA

18. Studies on the Mechanism of FV-1 Restriction: Properties of Determinants Specifying Viral Tropism

III. Transformation and Differentiation

19. Germ Line Integration and Leukemogenesis of Exogenous and Endogenous Murine Leukemia Viruses

20. In Vitro Lymphoid Cell Transformation by Abelson Murine Leukemia Virus

21. In Vitro Transformation of Specific Target Cells by Avian Leukemia Viruses

22. Distribution and Function of Defined Regions of Avian Tumor Virus Genomesin Viruses and Uninfected cells

23. Mechanisms of the H-2 Effect on Viral Leukemogenesis

IV. Human Oncornaviruses

24. Interspecies Transfer of RNA Tumor Virus Genes: Implications for the Search for "Human" Type C Viruses

25. Some Evidence for Infectious Type-C Virus in Humans

26. Spontaneous Type C Virus Expression in Human Embryonic Lung Cells (HEL-12): Comparison of Cloned and Mixed Cell Populations

V. Negative Strand Viruses

27. A Transcriptional Map of Vesicular Stomatitis Virus

28. Evidence for the Synthesis of a 'Leader' RNA Segment followed by the Sequential Transcription of the Genes of Vesicular Stomatitis Virus

29. Activation of Parainfluenza Viruses through Host-Dependent Cleavage of an Envelope Glycoprotein

30. The Molecular Organization of Sendai Virus Nucleocapsids

31. Supramolecular Organization of Proteins in Newcastle Disease Virus

32. Influenza Viral RNA Transcripts Synthesized In Vivo and In Vitro

33. The Structure of the RNA of Uukuniemi Virus, A Proposed Bunyavirus

VI. Plant Viruses

34. Structure and Replication of Plant Viroids

35. Complementarity Between Potato Spindle Tuber Vitroid and Cellular DNA: Measurement by RNA-DNA Hybridization

36. Translation and Structure of the RNAs of Brome Mosaic Virus

37. Translation of Tobacco Mosaic Virus RNA

38. Novel Sequencing Techniques Applied to the "tRNA-Like" 3'-Terminus of Turnip Yellow Mosaic Virus RNA

VII. Herpes Viruses

39. Genetics of Herpesvirus

40. The DNA of Epstein-Barr Virus Fragments Produced by Restriction Enzymes: Homologous DNA and RNA in Lymphoblastoid Cells

41. Expression and Regulation of Epstein-Barr Virus in Mammalian Cells

VIII. Viral Protein Synthesis

42. 5'-Terminal 7-Methylguanosine in Viral mRNAs and Its Role in Translation

43. Synthesis of the Polymerase Polypeptides of Semliki Forest Virus

44. Biosynthesis and Processing of Rauscher Leukemia Viral Precursor Polyp roteins

45. Regulation of Protein Synthesis in EMC Virus Infected Cells

IX. Mechanisms of Viral Persistance

46. The Role of Major Histocompatibility Antigens in Cell-Mediated Immunity to Virus Infections

47. Establishment and Detection of Animal DNA Proviruses in Cell Culture Systems

48. Defective Interfering Virus Particles Attenuate Virus Lethality In Vivo and In Vitro

49. Hepatitis B Virus: A Cause of Persistent Virus Infection in Man

Author Index

Subject Index


No. of pages:
© Academic Press 1976
Academic Press
eBook ISBN:

About the Editor

David Baltimore

Microbiologist, educator. Gairdner Foundation Annual Award, 1975; US Steel Award in Molecular Biology, 1974. Nobel Prize for Medicine, 1975.

Affiliations and Expertise

California Institute of Technology, Pasadena, U.S.A.

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