Description

Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field.

Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences.

Key Features

  • Highlights the latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseases
  • Provides firsthand accounts of the use of biotechnology tools, including molecular markers, stem cells, and tissue engineering

Readership

students of biotechnology, biochemistry, molecular medicine, genetics, genomics and other life science courses; researchers in these areas

Table of Contents

Dedication

Contributors

Foreword

Preface

Acknowledgments

Section I: Human Diseases: In Vivo and In Vitro Models

Chapter 1. Drosophila: A Model for Biotechnologists

Abstract

Acknowledgments

Summary

What You Can Expect to Know

History and Methods

History

Principle

Methodology

Ethical Issues

Translational Significance

Drosophila Models of Human Disease

Drosophila-Based Therapeutic Peptide Production

World Wide Web Resources

References

Further Reading

Glossary

Abbreviations

Long Answer Questions

Short Answer Questions

Answers to Short Answer Questions

Chapter 2. Animal Models of Tuberculosis

Abstract

Summary

What You Can Expect to Know

History and Methods

Comparative Pathology of TB in Humans and Animals

Pathogen Diversity: Crossing Species Barriers

Host Diversity: Fundamental Processes and Fine Tuning

Animal Models of TB: Limits and Lessons

Various Animal Models

Ethical Issues

Translational Significance

World Wide Web Resources

Protocols

References

Further Reading

Glossary

Abbreviations

Long Answer Questions

Short Answer Questions

Answers to Short Answer Questions

Chapter 3. Animal Models for Neurodegenerative Disorders

Abstract

Acknowledgments

Summary

What You Can Expect to Know

History and Methods

Principles

Methodology

Examples and Their Applications

Ethical Issues

Translational Significance

World Wide Web Resources

References

Further Reading

Glossary

Abbreviations

Long Answer Questions

Short Answer Questions

Answers to Short Answer Questions

Details

No. of pages:
668
Language:
English
Copyright:
© 2014
Published:
Imprint:
Academic Press
Print ISBN:
9780124160026
Electronic ISBN:
9780123914347