Description

Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field.

Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences.

Key Features

  • Highlights the latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseases
  • Provides firsthand accounts of the use of biotechnology tools, including molecular markers, stem cells, and tissue engineering

Readership

students of biotechnology, biochemistry, molecular medicine, genetics, genomics and other life science courses; researchers in these areas

Table of Contents

Dedication

Contributors

Foreword

Preface

Acknowledgments

Section I: Human Diseases: In Vivo and In Vitro Models

Chapter 1. Drosophila: A Model for Biotechnologists

Abstract

Acknowledgments

Summary

What You Can Expect to Know

History and Methods

History

Principle

Methodology

Ethical Issues

Translational Significance

Drosophila Models of Human Disease

Drosophila-Based Therapeutic Peptide Production

World Wide Web Resources

References

Further Reading

Glossary

Abbreviations

Long Answer Questions

Short Answer Questions

Answers to Short Answer Questions

Chapter 2. Animal Models of Tuberculosis

Abstract

Summary

What You Can Expect to Know

History and Methods

Comparative Pathology of TB in Humans and Animals

Pathogen Diversity: Crossing Species Barriers

Host Diversity: Fundamental Processes and Fine Tuning

Animal Models of TB: Limits and Lessons

Various Animal Models

Ethical Issues

Translational Significance

World Wide Web Resources

Protocols

References

Further Reading

Glossary

Abbreviations

Long Answer Questions

Short Answer Questions

Answers to Short Answer Questions

Chapter 3. Animal Models for Neurodegenerative Disorders

Abstract

Acknowledgments

Summary

What You Can Expect to Know

History and Methods

Principles

Methodology

Examples and Their Applications

Ethical Issues

Translational Significance

World Wide Web Resources

References

Further Reading

Glossary

Abbreviations

Long Answer Questions

Short Answer Questions

Answers to Short Answer Questions

Details

No. of pages:
668
Language:
English
Copyright:
© 2014
Published:
Imprint:
Academic Press
eBook ISBN:
9780123914347
Print ISBN:
9780124160026
Print ISBN:
9780128100325

About the editors

Ashish Verma

He has published more than thirty articles in peer reviewed journals, co-edited five books, and authored five individual book chapters. Dr. Verma serves as Associate Editor of the Journal of Agricultural and Biological Research, Research Journal of Immunology, International Journal of Virology, Journal of Pharmacology and Toxicology, Journal of Pharmacy and Bioallied Sciences and Advances in Integrative Omics and Applied Biotechnology. He also serves as Chief Editor of Biolixer and is a full member of the Indian Immunology Society, the Association of Microbiologists of India, the Society of Biological Chemists, the Society of Toxicology, the Indian Science Congress, and the Biotechnology Society of India. Dr. Ashish has been an invited guest speaker at numerous international scientific meetings, chaired ten scientific meetings in India and abroad, and received research grants and awards from the Indian Ministry of Education, the Council of Scientific and Industrial Research, the International Union of Immunology, the Weizmann Institute of Science, and the Catholic University of Rome among other organizations.

Affiliations and Expertise

Dr. Ashish S. Verma is Professor and Pro-Vice-Chancellor at Jadavpur University, Kolkatta, India and previously served as Professor at Amity Institute of Biotechnology, Amity University, Uttar Pradesh, India

Anchal Singh

Dr. Singh teaches biochemistry and immunology to post graduate students at Baranas Hindu University and her research interests and areas of expertise include parasite immunology, immunodiagnostics, animal cell cultures, in vitro assays, and antibiotic resistance in bacteria. Her research has been funded by the Indian Department of Science and Technology and the Indian Department of Biotechnology. She has co-edited five books, authored articles for peer reviewed journals, and authored nine individual book chapters in her various research areas. Additionally, Dr. Singh is a full member of the Association of Microbiologists of India, the Society of Biological Chemists, and AIDSCON and has served as Treasurer of “National Symposium on HIV and AIDS: Biology to Bedside” held at Amity University (2012), the “International Symposium on Frontiers in Cancer Research: Prevention to Therapeutics” at Amity University (2013), and the “26th National Congress of Parasitology” held at Banaras Hindu University (2016).

Affiliations and Expertise

Dr. Anchal Singh is an Assistant Professor in the Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, India and previously served as Assistant Professor at Amity University, Uttar Pradesh, India.