Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Volume 31 deals with the mechanisms of anesthetic actions under normal conditions as well as pathophysiologic states.

Key Features

@introbul:Key Features @bul:* Covers anesthetics and cardiac function * Addresses disorders of the cardiovascular system and associated diseases * Explains therapeutic and pathophysiological implications * Details reflex regulation of peripheral circulation * Includes full descriptions of the latest methodologies * Written by internationally recognized experts in the field of anesthesia research


Researchers, students in pharmacology, cardiovascular physiology, academic cardiologists, and anesthesiologists.

Table of Contents

Cardiac Muscle: N. Sperelakis, Regulation of the Calcium Slow Channels of Heart by Cyclic Nucleotides and Effects of Ischemia. P.F. Wouters, H. Van Aken, M. Van de Velde, M.A.E. Marcus, and W. Flameng, Functional Adaptation to Myocardial Ischemia: Interaction with Volatile Anesthetics in Chronically Instrumented Dogs. D.F. Stowe, Excitation-Contraction Uncoupling and Vasodilators for Long-Term Cold Preservation of Isolated Hearts. H. Machler, H.Gombotz, K. Sabin, and H. Metzler, Troponin T as a Marker of Perioperative Myocardial Cell Damage. A.G. Hedman, Silent Myocardial Ischemia: Pathophysiology and Perioperative Management. B. Drenger, Y. Ginosar, and Y. Gozal, Effect of Halothane on Sarcolemmal Calcium Channels during Myocardial Ischemia and Reperfusion. D.M. Van Winkle, G.L. Chien, and R.F. Davis, Myocardial Ischemic Preconditioning. P.R. Knight, M.D. Smith, and B.A. Davidson, Effects of Hypoxia/Reoxygenation on Intracellular Calcium Ion Homeostasis in Ventricular Myocytes during Halothane Exposure. P.S. Pagel and D.C. Warltier, Mechanical Consequences of Calcium Channel Modulation during Volatile Anesthetic-Induced Left Ventricular Systolic and Diastolic Dysfunction. N. Miao, M.J. Frazer, and C. Lynch, III, Anesthetic Actions on Calcium Uptake and Calcium-Dependent Adenosine Triphosphatase Activity of Cardiac Sarcoplasmic Reticulum. L.A. Turner, S. Vodanovic, and Z.J. Bosnjak, Interaction of Anesthetics and Catecholamines on Conduction in the Canine His-Purkinje System. J.L. Atlee, III, M.N. Vicenzi, H.J. Woehlck, and Z.J. Bosnjak, Anesthetics, Catecholamines, and Ouabain on Automaticity of Primary and Secondary Pacemakers. T.J.J. Blanck, D.L. Lee, S. Yasukochi, C. Ho


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© 1994
Academic Press
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@from:Praise for the Serial @qu:"The book provides superb reading material which chemists and pharmacologists interested in the area of chemotherapy will surely enjoy reading." @source:--JOURNAL OF PHARMACEUTICAL SCIENCES