
Analysis of Complex Disease Association Studies
A Practical Guide
Description
Key Features
- Easy access to key information including advantages and disadvantage of tests for particular applications, identification of databases, languages and their capabilities, data management risks, frequently used tests
- Extensive list of references including links to tutorial websites
- Case studies and Tips and Tricks
Readership
Table of Contents
Chapter 1 Genetic architecture of complex disease
Chapter 2 Population genetics and linkage disequilibrium
Chapter 3 Genetic association study design
Chapter 4 Selection of SNPs
Chapter 5 Genotype calling
Chapter 6 Data handling
Chapter 7 Data quality control
Chapter 8 Single-locus tests of association for population-based studies
Chapter 9 Population structure
Chapter 10 Haplotype-based methods
Chapter 11 Interaction analyses
Chapter 12 Copy number variant analysis
Chapter 13 Analysis of family-based association studies
Chapter 14 Bioinformatics approaches
Chapter 15 Interpreting association signals
Chapter 16 Delineating association signals
Chapter 17 Case study: obesity
Chapter 18 Case study: rheumatoid arthritis
Product details
- No. of pages: 340
- Language: English
- Copyright: © Academic Press 2010
- Published: October 20, 2010
- Imprint: Academic Press
- eBook ISBN: 9780123751430
- Hardcover ISBN: 9780123751423
About the Editors
Eleftheria Zeggini
Affiliations and Expertise
Andrew Morris
Affiliations and Expertise
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