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Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses
Proceedings of a IUPHAR Satellite Symposium in Conjunction with the 8th International Congress of Pharmacology, Paris, France, July 27-29, 1981
1st Edition - April 29, 1982
Editors: P. Lechat, S. Thesleff, W. C. Bowman
Language: English
eBook ISBN:9781483150437
9 7 8 - 1 - 4 8 3 1 - 5 0 4 3 - 7
Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses presents the proceedings of a IUPHAR Satellite Symposium in conjunction with the eighth…Read more
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Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses presents the proceedings of a IUPHAR Satellite Symposium in conjunction with the eighth International Congress of Pharmacology held in Paris, France on July 27-29, 1981. The book contains papers on the effects of aminopyridines on ionic currents in excitable membranes; the effects of aminopyridines on synaptic transmission; and the effects of aminopyridines on the release of chemical transmitters. The text also presents papers on some differences in the blockade of potassium permeabilities by apamin and the aminopyridines; the miscellaneous actions of aminopyridines and related compounds; and the effects of aminopyridines on the skeletal, smooth and cardiac muscle. The clinical applications of aminopyridines and further miscellaneous actions of aminopyridines and related compounds are also considered.
List of Participants
Scientific Sessions
Historical review
Aminopyridines and Ionic Currents in Excitable Memebranes
General review on potassium currents in exitable membranes of nerve and muscle
Effects of Aminopyridines on Potassium currents of the Nodal Membrane
Properties and Physiological Roles of K+ Currents in Frog Myelinated Nerve Fibres as Revealed by 4-aminopyridine
Effects of Aminopyridines on Ionic Currents and Ionic Channel Noise in Unrnyelinated Axons
3- and 4-Aminopyridine in Synaptic Transmission at the Squid Giant Synapse
Discussion
Aminopyridines and Synaptic Transmission
Lectures
General Principles of Synaptic Transmission
Effects of Aminopyridines on Neuromuscular Transmission
Effects of 4-Aminopyridine on Transmission in Excitatory and Inhibitory synapses in the spinal cord
The Influence of 4-Aminopyridine on Parasympathetic Transmission
Discussion
Aminopyridines and the Release of Chemical Transmitters: Contrast with Apamin