Albumin: Structure, Function and Uses - 1st Edition - ISBN: 9780080196039, 9781483156880

Albumin: Structure, Function and Uses

1st Edition

Editors: Victor M. Rosenoer Murray Oratz Marcus A. Rothschild
eBook ISBN: 9781483156880
Imprint: Pergamon
Published Date: 1st January 1977
Page Count: 412
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Description

Albumin Structure, Function and Uses reviews the many facets of serum albumin, including its history and evolutionary development, structure and function, synthesis, degradation, distribution and transport, and metabolic behavior. The use, misuse, and abuse of albumin in the treatment of disease are also discussed.
This book is comprised of 17 chapters and begins with a commentary on how albumin is used, misused, and abused in the treatment of disease such as peptic ulcer, and a description of the real indications for its use. Concepts in albumin purification are then examined, along with the amino acid sequence of serum albumin and some aspects of its structure and conformational properties. Subsequent chapters explore the phylogenetics of albumin; albumin binding sites; clinical implications of drug-albumin interaction; genetics of human serum albumin; and hepatic synthesis of export proteins. Albumin catabolism and intracellular transport are also considered, together with surgical and clinical aspects of albumin metabolism.
This monograph should be a useful resource for biochemists and clinicians.

Table of Contents


Contributors

Preface

Acknowledgments

Introduction. The Use, Misuse and Abuse of Albumin Infusions

Current Concepts Concerning Albumin Purification

Serum Albumin: Amino Acid Sequence

Some Aspects of the Structure And Conformational Properties of Serum Albumin

Albumin Phylogenetics

The Genetics of Human Serum Albumin

Albumin Binding Sites

Clinical Implications of Drug-Albumin Interaction

Enzyme-Like Activities Associated with Albumin

Hepatic Synthesis of Export Proteins

Albumin Synthesis

Albumin Catabolism

Albumin-Osmotic Function

Interstitial Albumin

Intracellular Albumin Transport

Surgical Aspects of Albumin Metabolism

Clinical Aspects of Albumin Metabolism

Author Index

Subject Index

Details

No. of pages:
412
Language:
English
Copyright:
© Pergamon 1977
Published:
Imprint:
Pergamon
eBook ISBN:
9781483156880

About the Editor

Victor M. Rosenoer

Murray Oratz

Marcus A. Rothschild