Albumin: Structure, Function and Uses

Albumin: Structure, Function and Uses

1st Edition - January 1, 1977

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  • Editors: Victor M. Rosenoer, Murray Oratz, Marcus A. Rothschild
  • eBook ISBN: 9781483156880

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Albumin Structure, Function and Uses reviews the many facets of serum albumin, including its history and evolutionary development, structure and function, synthesis, degradation, distribution and transport, and metabolic behavior. The use, misuse, and abuse of albumin in the treatment of disease are also discussed. This book is comprised of 17 chapters and begins with a commentary on how albumin is used, misused, and abused in the treatment of disease such as peptic ulcer, and a description of the real indications for its use. Concepts in albumin purification are then examined, along with the amino acid sequence of serum albumin and some aspects of its structure and conformational properties. Subsequent chapters explore the phylogenetics of albumin; albumin binding sites; clinical implications of drug-albumin interaction; genetics of human serum albumin; and hepatic synthesis of export proteins. Albumin catabolism and intracellular transport are also considered, together with surgical and clinical aspects of albumin metabolism. This monograph should be a useful resource for biochemists and clinicians.

Table of Contents

  • Contributors



    Introduction. The Use, Misuse and Abuse of Albumin Infusions

    Current Concepts Concerning Albumin Purification

    Serum Albumin: Amino Acid Sequence

    Some Aspects of the Structure And Conformational Properties of Serum Albumin

    Albumin Phylogenetics

    The Genetics of Human Serum Albumin

    Albumin Binding Sites

    Clinical Implications of Drug-Albumin Interaction

    Enzyme-Like Activities Associated with Albumin

    Hepatic Synthesis of Export Proteins

    Albumin Synthesis

    Albumin Catabolism

    Albumin-Osmotic Function

    Interstitial Albumin

    Intracellular Albumin Transport

    Surgical Aspects of Albumin Metabolism

    Clinical Aspects of Albumin Metabolism

    Author Index

    Subject Index

Product details

  • No. of pages: 412
  • Language: English
  • Copyright: © Pergamon 1977
  • Published: January 1, 1977
  • Imprint: Pergamon
  • eBook ISBN: 9781483156880

About the Editors

Victor M. Rosenoer

Murray Oratz

Marcus A. Rothschild

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