Description

Advances in Immunology, a long established and highly respected serial, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Readership

Immunologists and infectious disease specialists, cell biologists and hematologists

Table of Contents

Discovery of Activation-Induced Cytidine Deaminase, the Engraver of Antibody Memory DNA Deamination in Immunity: Aid in the Context of Its Apobec Relatives The Role of Activation Induced Deaminase in Antibody Diversification and Chromosome Translocations Targeting of AID-mediated Sequence Diversification by cis-acting Determinants AID-initiated Purposeful Mutations in Immunoglobulin Genes Post-translational AID Regulation Beyond SHM and CSR: AID and Related Cytidine Deaminases in the Host Response to Viral Infection AID expression and tumorigenesis Pathophysiology of B Cell Intrinsic Immunoglobulin Class Switch Recombination Deficiencies

Details

No. of pages:
344
Language:
English
Copyright:
© 2007
Published:
Imprint:
Academic Press
Print ISBN:
9780123737069
Electronic ISBN:
9780080545929