Adverse Reactions to Drugs

Adverse Reactions to Drugs, Second Edition focuses on the problems posed by the adverse responses to drugs, as well as drug interactions, dosage, and drug metabolism.

The publication first tackles adverse reactions and factors which predispose to adverse drug reactions. Topics include dose adjustment, overdose, renal failure, cumulation, side effects, drug allergy, cumulative overdose, and delayed effects. The text then ponders on drug interactions, including renal excretion, drug metabolism, mutual toxicity, and interactions affecting transport to site of action.

The manuscript examines adverse reactions in dental practice, drugs used in pregnancy, the neonate, and lactation, and problems for the pharmaceutical industry before marketing a new drug. Discussions focus on ethical problems of drug studies in man, pregnancy, hemorrhage, oxygen toxicity, chloramphenicol, drugs and lactation, drugs used in dental practice, and local anesthetics. The book then elaborates on monitoring adverse reactions to drugs and the therapeutic audit and drug regulatory bodies and their problems.

The publication is a valuable source of data for doctors and dentists wanting to focus on research on the adverse reaction to drugs.

Preface to Second Edition

Acknowledgments

Chapter I The Dawn of Concern

Chapter I1 Adverse Reactions

Chapter I11 Factors which Predispose to Adverse Reactions

Chapter IV Drug Interactions

Chapter V Adverse Reactions in Dental Practice

Chapter VI Drugs used in Pregnancy the Neonate and Lactation

Chapter VII Problems for the Pharmaceutical Industry Before Marketing a New Drug

Chapter VIII Monitoring Adverse Reactions to Drugs and the Therapeutic Audit

Chapter IX Drug Regulatory Bodies and their Problems

Chapter X The Future

Appendix I Adverse Reactions to Drugs

Appendix I1 Drug Induced Disease

Appendix I11 Drugs Interaction Tables

Appendix IV Drugs in Pregnancy

References

Index

Drug Index