
Advances in Virus Research
Description
Key Features
- Contributions from leading authorities
- Informs and updates on all the latest developments in the field
Readership
Virologists, microbiologists and infectious diseases specialists
Table of Contents
Series Page
Contributors
In Memoriam
Aaron Shatkin (1934–2012)
Chapter One. Regulation of Retroviral Polyadenylation
Abstract
Abbreviations
1 Cellular Polyadenylation
2 Retroviral Long Terminal Repeats
3 Retroviruses with the Poly(A) Signal Located in the U3 Region
4 Retroviruses Encoding the Poly(A) Signal in the R Region
5 Conclusions
Acknowledgments
References
Chapter Two. Open Questions About Giant Viruses
Abstract
1 Background
2 The Traditional View: Viruses Started Small, Got Bigger
3 Genome Reduction: A Neutral Ratchet Wheel Generating the Diversity of Large DNA Viruses
4 Speculation on the Nature of the Giant Virus Ancestor
Acknowledgments
References
Chapter Three. Assembly and Budding of Negative-Strand RNA Viruses
Abstract
1 Introduction
2 Virion Structure: The Final Product
3 Steps in Assembly of Virus Budding Sites
4 Role of Membrane Microdomains in Assembly of Envelope Glycoproteins
5 Assembly of Viral Matrix Proteins
6 Selection of Nucleocapsids
7 Late Budding Functions and Virus Release
8 Back to the Beginning: How is Assembly Initiated?
9 Perspectives for the Future
References
Chapter Four. Arthropod-Borne Flaviviruses and RNA Interference: Seeking New Approaches for Antiviral Therapy
Abstract
1 Introduction
2 The RNA Interference Mechanism and its Antiviral Effects
3 Arthropod-Borne Flaviviruses
4 RNAi and the Mosquito Vector
5 The Interplay Between Arthropod-Borne Flaviviruses and the Endogenous Host Cell RNAi Pathway
6 Conclusions and Challenges
Acknowledgments
References
Index
Product details
- No. of pages: 128
- Language: English
- Copyright: © Academic Press 2013
- Published: February 18, 2013
- Imprint: Academic Press
- eBook ISBN: 9780124080638
- Hardcover ISBN: 9780124081161
About the Editors
Karl Maramorosch
Affiliations and Expertise
Frederick Murphy
