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Advances in Virus Research - 1st Edition - ISBN: 9780124076983, 9780124078475

Advances in Virus Research, Volume 87

1st Edition

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Editors: Karl Maramorosch Frederick Murphy
Hardcover ISBN: 9780124076983
eBook ISBN: 9780124078475
Imprint: Academic Press
Published Date: 11th July 2013
Page Count: 264
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Table of Contents

Series Page


Chapter One. Mechanisms of Reovirus Bloodstream Dissemination

1 Introduction

2 Dynamics of Reovirus Infection in the Intestine and Lung

3 Hematogenous Spread of Reovirus

4 Neural Dissemination of Reovirus

5 Function of Hematogenous and Neural Spread in Reovirus Pathogenesis

6 Unanswered Questions and Future Directions



Chapter Two. Molecular Biology and Epidemiology of Dianthoviruses

1 Introduction

2 Dianthoviruses

3 Economic Importance of Diseases Caused by Dianthoviruses

4 Molecular Biology of Dianthovirus

5 Transmission Studies and Epidemiology

6 Effects on Environment

7 Concluding Remarks and Perspectives



Chapter Three. Viral and Nonviral Elements in Potexvirus Replication and Movement and in Antiviral Responses

1 Introduction

2 Elements That Regulate Potexvirus Replication

3 Elements That Regulate Potexvirus Movement

4 Elements Involved in Antiviral Responses

5 Conclusions



Chapter Four. Influenza Virus Transcription and Replication

1 Introduction

2 Molecular Biology of Influenza Virus Transcription and Replication

3 Structural Elements of the Influenza Virus Transcription–Replication Machine

4 Mechanisms of Influenza Virus Transcription and Replication

5 Role of Host Cell Factors

6 Outlook



Chapter Five. The Molecular Biology of Ilarviruses

1 Introduction

2 Virion and Genome Structure

3 Taxonomy and Genetic Diversity

4 Genome Expression

5 CP–RNA Interaction and Genome Activation

6 Virus Movement Within and Among Plants

7 Host Responses

8 Synergy Among Ilarviruses

9 Some Conclusions and Many Questions



Chapter Six. Genetic Variation and HIV-Associated Neurologic Disease

1 Introduction

2 Overview of HIV-1 CNS Pathogenesis

3 Clinical Diagnoses of HIV-1 CNS Infection

4 The Evolution and Adaptation of HIV-1 and the Establishment of Molecular Diversity

5 Molecular Diversity of HIV-1 Env and Neurologic Disease

6 Genetic Diversity Within HIV-1 Tat, Vpr, and the LTR, and Its Contribution to the Onset and Severity of HIV-1-Associated Neurological System Disease

7 Sequence Variation of Specific Transcription Factor-Binding Sites Within the HIV-1 LTR and Its Correlation with Nervous System Disease

8 Host Genetic Determinants of HIV-1 Infection and CNS Disease

9 Conclusion





Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology.

Key Features

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field


Virologists, microbiologists and infectious diseases specialists.


No. of pages:
© Academic Press 2013
11th July 2013
Academic Press
Hardcover ISBN:
eBook ISBN:


"A mandatory purchase for all types of comprehensive libraries, both public and university, as well as for those interested in or doing research in the field of virology."- MILITARY MEDICINE

"This well known to virologists. It is a valuable aid in maintaining an overview of various facets of the rapidly expanding fields of virology...Timely, informative, and useful to the student, teacher, and research scientist."--AMERICAN SCIENTIST

Ratings and Reviews

About the Editors

Karl Maramorosch

Professor Karl Maramorosch works at Rutgers University, New Brunswick, NJ, USA.

Affiliations and Expertise

Rutgers University, New Brunswick, NJ, USA

Frederick Murphy

Frederick Murphy

Frederick A. Murphy, DVM, PhD, is professor, Department of Pathology, University of Texas Medical Branch (UTMB), Galveston. He holds a BS and DVM from Cornell University and a PhD from the University of California, Davis (UC Davis). Formerly he was dean and distinguished professor, School of Veterinary Medicine, and distinguished professor, School of Medicine, UC Davis. Before that he served as director of the National Center for Infectious Diseases, and director of the Division of Viral and Rickettsial Diseases, Centers for Disease Control, Atlanta. He is a member of the Institute of Medicine of the U.S. National Academy of Sciences and is a member of the German National Academy of Sciences and the Belgian Royal Academy of Medicine. He holds an honorary Doctor of Medicine and Surgery from the University of Turku, Finland; an honorary Doctor of Science from the University of Guelph, Canada; an honorary Doctor of Veterinary Medicine from the University of London, United Kingdom; an honorary Doctor of Science from University College Dublin, Ireland; the Presidential Rank Award of the U.S. Government; the PennVet World Leadership Award from the University of Pennsylvania, and the Distinguished Microbiologist Award from the American College of Veterinary Microbiologists. At UTMB, he is a member of the Institute for Human Infections and Immunity, Center for Biodefense and Emerging Infectious Diseases, Galveston National Laboratory, and McLaughlin Endowment for Infection and Immunity. His professional interests include the pathology and epidemiology of highly pathogenic viruses/viral diseases: rabies and the rabies-like viruses, arboviruses, hemorrhagic fever viruses, and other neurotropic viruses. He has been a leader in advancing the concepts of “new and emerging infectious diseases” and “new and emerging zoonoses” and “the threat posed by bioterrorism.” Most recently, he has been working on Internet resources on the history of virology: “The Foundations of Virology” at

Affiliations and Expertise

University of Texas Medical Branch, Galveston, TX, USA