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- Chapter One: Biomedical and Catalytic Opportunities of Virus-Like Particles in Nanotechnology
- 1 What Is a Virus-Like Particle?
- 2 The Essentials of Protein VLP Structure
- 3 VLPs as Materials
- 4 VLPs as Templates for Constrained Material Synthesis
- 5 VLPs for Biomedical Delivery and Imaging
- 6 VLPs as Metabolic Compartments
- 7 VLPs as Stimulants of Immunity
- 8 Outlook
- Chapter Two: A Renaissance in Nepovirus Research Provides New Insights Into Their Molecular Interface With Hosts and Vectors
- 1 Introduction
- 2 Taxonomy and Genome Structure
- 3 Population Structure, Genetic Diversity, and Evolution
- 4 Genome Expression by Cap-Independent Translation and Polyprotein Processing
- 5 Replication Proteins and Assembly of Replication Complexes
- 6 Virion Structure and Encapsidation
- 7 Viral and Plant Factors Implicated in Cell-to-Cell Movement
- 8 Host Defense and Virus Counter-Defense Responses
- 9 Viral Symptom Determinants
- 10 Transmission
- 11 Disease Management
- 12 Conclusions and Future Prospects
- Chapter Three: Have NEC Coat, Will Travel: Structural Basis of Membrane Budding During Nuclear Egress in Herpesviruses
- 1 Introduction
- 2 The Role of NEC in Membrane Budding
- 3 NEC Structures
- 4 The Hexagonal Lattice of the NEC: Structure and Function
- 5 NEC Lattice Curvature
- 6 Regulation of NEC Lattice Assembly
- 7 NEC and Capsid Deenvelopment at the ONM
- 8 Summary
- Chapter Four: Nonsegmented Negative-Sense RNA Viruses—Structural Data Bring New Insights Into Nucleocapsid Assembly
- 1 The Nonsegmented Negative-Sense RNA Viruses
- 2 The RNA Replication Complex
- 3 The N0–P Complex
- 4 A Proposed Scenario for NC Handling and Assembly by the RNA Polymerase Complex
- 5 Conclusions and Future Directions
- Chapter Five: Modified Vaccinia Virus Ankara: History, Value in Basic Research, and Current Perspectives for Vaccine Development
- 1 Introduction
- 2 History and Development of MVA
- 3 MVA as Tool for Research in Poxvirus Biology
- 4 Recombinant MVA Vaccines Against Infectious Diseases
- 5 MVA as Third-Generation Vaccine Against Smallpox
- 6 Conclusions
Advances in Virus Research volume 97, the latest in the series first published in 1953, covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology.
- Contains contributions from leading authorities
- Informs and updates on all the latest developments in the field of virology
Virologists, microbiologists and infectious disease specialists
- No. of pages:
- © Academic Press 2017
- 5th January 2017
- Academic Press
- Hardcover ISBN:
- eBook ISBN:
Professor Margaret Kielian works at the Department of Cell Biology, Albert Einstein College of Medicine, New York, USA.
Department of Cell Biology, Albert Einstein College of Medicine, NY, USA
Born: March 18, 1957 in Goeppingen, Germany
1963-1967: Elementary School
1967-1976: High School (Gymnasium)
1976: Diploma (Abitur)
1976-1977: Compulsory Military Service
1977-1982: Study of biology at Tuebingen University, Germany
1982-1985: Ph.D. work at Federal Research Centre for Virus Diseases of Animals,
1985: Ph.D. in Genetics
1986-1987: Postdoctoral Fellow at Vanderbilt University, Nashville, TN
Department of Microbiology
1988-today: Federal Research Centre for Virus Diseases of Animals
1990: Habilitation (prerequisite for professorship)
since 1994: Director of the Institute of Molecular Biology at the Federal Research Centre for Virus Diseases of Animals, Insel Riems, Germany
since 1996: President of the Federal Research Centre for Virus Diseases of Animals (renamed in 2004 'Friedrich-Loeffler-Institut')
since 1997: Professor of Virology at University of Greifswald
More than 300 peer-reviewed publications in international journals (listed in PubMed) on different aspects of infectious animal diseases.
Institute of Molecular Biology, Friedrich-Loeffler-Institut, Greifswald, Germany
Prof. Marilyn J. Roossinck works at the Center for Infectious Disease Dynamics, Pennsylvania State University, Pennsylvania, U.S.A
Pennsylvania State University, PA, USA
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