Advances in Virus Research

Advances in Virus Research

1st Edition - January 2, 2017

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  • Editors: Margaret Kielian, Thomas Mettenleiter, Marilyn Roossinck
  • Hardcover ISBN: 9780128118016
  • eBook ISBN: 9780128118023

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Advances in Virus Research volume 97, the latest in the series first published in 1953, covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology.

Key Features

  • Contains contributions from leading authorities
  • Informs and updates on all the latest developments in the field of virology


Virologists, microbiologists and infectious disease specialists

Table of Contents

    • Chapter One: Biomedical and Catalytic Opportunities of Virus-Like Particles in Nanotechnology
      • Abstract
      • 1 What Is a Virus-Like Particle?
      • 2 The Essentials of Protein VLP Structure
      • 3 VLPs as Materials
      • 4 VLPs as Templates for Constrained Material Synthesis
      • 5 VLPs for Biomedical Delivery and Imaging
      • 6 VLPs as Metabolic Compartments
      • 7 VLPs as Stimulants of Immunity
      • 8 Outlook
      • Acknowledgments
    • Chapter Two: A Renaissance in Nepovirus Research Provides New Insights Into Their Molecular Interface With Hosts and Vectors
      • Abstract
      • 1 Introduction
      • 2 Taxonomy and Genome Structure
      • 3 Population Structure, Genetic Diversity, and Evolution
      • 4 Genome Expression by Cap-Independent Translation and Polyprotein Processing
      • 5 Replication Proteins and Assembly of Replication Complexes
      • 6 Virion Structure and Encapsidation
      • 7 Viral and Plant Factors Implicated in Cell-to-Cell Movement
      • 8 Host Defense and Virus Counter-Defense Responses
      • 9 Viral Symptom Determinants
      • 10 Transmission
      • 11 Disease Management
      • 12 Conclusions and Future Prospects
      • Acknowledgments
    • Chapter Three: Have NEC Coat, Will Travel: Structural Basis of Membrane Budding During Nuclear Egress in Herpesviruses
      • Abstract
      • 1 Introduction
      • 2 The Role of NEC in Membrane Budding
      • 3 NEC Structures
      • 4 The Hexagonal Lattice of the NEC: Structure and Function
      • 5 NEC Lattice Curvature
      • 6 Regulation of NEC Lattice Assembly
      • 7 NEC and Capsid Deenvelopment at the ONM
      • 8 Summary
      • Acknowledgments
    • Chapter Four: Nonsegmented Negative-Sense RNA Viruses—Structural Data Bring New Insights Into Nucleocapsid Assembly
      • Abstract
      • 1 The Nonsegmented Negative-Sense RNA Viruses
      • 2 The RNA Replication Complex
      • 3 The N0–P Complex
      • 4 A Proposed Scenario for NC Handling and Assembly by the RNA Polymerase Complex
      • 5 Conclusions and Future Directions
      • Acknowledgments
    • Chapter Five: Modified Vaccinia Virus Ankara: History, Value in Basic Research, and Current Perspectives for Vaccine Development
      • Abstract
      • 1 Introduction
      • 2 History and Development of MVA
      • 3 MVA as Tool for Research in Poxvirus Biology
      • 4 Recombinant MVA Vaccines Against Infectious Diseases
      • 5 MVA as Third-Generation Vaccine Against Smallpox
      • 6 Conclusions
    • Index

Product details

  • No. of pages: 258
  • Language: English
  • Copyright: © Academic Press 2017
  • Published: January 2, 2017
  • Imprint: Academic Press
  • Hardcover ISBN: 9780128118016
  • eBook ISBN: 9780128118023

About the Serial Editors

Margaret Kielian

Professor Margaret Kielian works at the Department of Cell Biology, Albert Einstein College of Medicine, New York, USA.

Affiliations and Expertise

Professor, Department of Cell Biology, Albert Einstein College of Medicine, NY, USA

Thomas Mettenleiter

Thomas Mettenleiter
Born: March 18, 1957 in Goeppingen, Germany

Nationality: German

1963-1967: Elementary School

1967-1976: High School (Gymnasium)

1976: Diploma (Abitur)

1976-1977: Compulsory Military Service

1977-1982: Study of biology at Tuebingen University, Germany

1982-1985: Ph.D. work at Federal Research Centre for Virus Diseases of Animals,

Tuebingen, Germany

1985: Ph.D. in Genetics

1986-1987: Postdoctoral Fellow at Vanderbilt University, Nashville, TN

Department of Microbiology

1988-today: Federal Research Centre for Virus Diseases of Animals

1990: Habilitation (prerequisite for professorship)

since 1994: Director of the Institute of Molecular Biology at the Federal Research Centre for Virus Diseases of Animals, Insel Riems, Germany

since 1996: President of the Federal Research Centre for Virus Diseases of Animals (renamed in 2004 'Friedrich-Loeffler-Institut')

since 1997: Professor of Virology at University of Greifswald

Scientific Work:

More than 300 peer-reviewed publications in international journals (listed in PubMed) on different aspects of infectious animal diseases.

Affiliations and Expertise

Institute of Molecular Biology, Friedrich-Loeffler-Institut, Greifswald, Germany

Marilyn Roossinck

Prof. Marilyn J. Roossinck works at the Center for Infectious Disease Dynamics, Pennsylvania State University, Pennsylvania, USA.

Affiliations and Expertise

Professor, Center for Infectious Disease Dynamics, Pennsylvania State University, Pennsylvania, USA

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