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Advances in Virus Research - 1st Edition - ISBN: 9780128048207, 9780128052365

Advances in Virus Research, Volume 95

1st Edition

Serial Editors: Margaret Kielian Karl Maramorosch Thomas Mettenleiter
Hardcover ISBN: 9780128048207
eBook ISBN: 9780128052365
Imprint: Academic Press
Published Date: 26th April 2016
Page Count: 236
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Table of Contents

Chapter One: Peste des Petits Ruminants Virus

  • Abstract
  • 1 Emergence of PPRV
  • 2 Host Range
  • 3 Current Distribution
  • 4 Virus Transmission and Spread
  • 5 Molecular Biology of the Virus
  • 6 Vaccines
  • 7 Diagnostics for PPRV
  • 8 Toward the Global Control and Eradication of PPR
  • 9 Areas for Future Research

Chapter Two: Cell-to-Cell Spread of HIV and Viral Pathogenesis

  • Abstract
  • 1 Introduction
  • 2 T-Cell Virological Synapse
  • 3 Infectious Synapses and trans-Infection
  • 4 Role of Cell-to-Cell Infection During Sexual Transmission
  • 5 Conclusions

Chapter Three: Future Scenarios for Plant Virus Pathogens as Climate Change Progresses

  • Abstract
  • 1 Introduction
  • 2 General Considerations
  • 3 Direct Climate Effects
  • 4 Indirect Climate Effects
  • 5 Implications for Control
  • 6 Information Gaps and Deficiencies
  • 7 Conclusions
  • Acknowledgments

Chapter Four: Autophagy and Mammalian Viruses: Roles in Immune Response, Viral Replication, and Beyond

  • Abstract
  • 1 The Autophagic Machinery in Mammalian Cells
  • 2 Autophagy in Innate Immune Control of Virus Infections
  • 3 Adaptive Antiviral Immune Responses Mediated by Autophagy
  • 4 Autophagy Manipulation by Viruses
  • 5 Unconventional Use of Autophagy Proteins
  • 6 Role of Autophagy in Virus Particle Release
  • 7 Conclusions and Future Directions
  • Acknowledgments

Chapter Five: Historical Perspective: What Constitutes Discovery (of a New Virus)?

  • Abstract
  • 1 The Unique Role of Ultrafiltration in the Development of Virology
  • 2 Proof That the Infectious Agent Is a Virus
  • 3 The Contemporary Sense of the Identity of a New Virus
  • 4 Proof That the New Virus Is the Etiologic Agent of the Disease (“Proof of Causation”)
  • 5 The Discovery and Discoverers of New Viruses
  • Acknowledgment


First published in 1953, the Advances in Virus Research series covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology.

Key Features

  • Contain contributions from leading authorities
  • Informs and updates on all the latest developments in the field of virology


Virologists, microbiologists and infectious disease specialists.


No. of pages:
© Academic Press 2016
26th April 2016
Academic Press
Hardcover ISBN:
eBook ISBN:

Ratings and Reviews

About the Serial Editors

Margaret Kielian

Professor Margaret Kielian works at the Department of Cell Biology, Albert Einstein College of Medicine, New York, USA.

Affiliations and Expertise

Department of Cell Biology, Albert Einstein College of Medicine, NY, USA

Karl Maramorosch

Professor Karl Maramorosch works at Rutgers University, New Brunswick, NJ, USA.

Affiliations and Expertise

Rutgers University, New Brunswick, NJ, USA

Thomas Mettenleiter

Thomas Mettenleiter

Born: March 18, 1957 in Goeppingen, Germany

Nationality: German

1963-1967: Elementary School

1967-1976: High School (Gymnasium)

1976: Diploma (Abitur)

1976-1977: Compulsory Military Service

1977-1982: Study of biology at Tuebingen University, Germany

1982-1985: Ph.D. work at Federal Research Centre for Virus Diseases of Animals,

Tuebingen, Germany

1985: Ph.D. in Genetics

1986-1987: Postdoctoral Fellow at Vanderbilt University, Nashville, TN

Department of Microbiology

1988-today: Federal Research Centre for Virus Diseases of Animals

1990: Habilitation (prerequisite for professorship)

since 1994: Director of the Institute of Molecular Biology at the Federal Research Centre for Virus Diseases of Animals, Insel Riems, Germany

since 1996: President of the Federal Research Centre for Virus Diseases of Animals (renamed in 2004 'Friedrich-Loeffler-Institut')

since 1997: Professor of Virology at University of Greifswald

Scientific Work:

More than 300 peer-reviewed publications in international journals (listed in PubMed) on different aspects of infectious animal diseases.

Affiliations and Expertise

Institute of Molecular Biology, Friedrich-Loeffler-Institut, Greifswald, Germany