Advances in Transition-Metal Mediated Heterocyclic Synthesis - 1st Edition - ISBN: 9780128116517

Advances in Transition-Metal Mediated Heterocyclic Synthesis

1st Edition

Editors: Daniel Sole Israel Fernandez
Paperback ISBN: 9780128116517
Imprint: Academic Press
Published Date: 1st June 2018
Page Count: 375
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Description

Advances in Transition-Metal Mediated Heterocyclic Synthesis provides an overview of recent catalytic reactions involving transition metals (palladium, platinum, rhodium, ruthenium, copper, iron, and gold) to produce heterocyclic compounds. The book is organized according to the type of transformation used to achieve the synthesis of the Heterocyclic systems (mainly aza- and oxa-heterocycles). As such, this useful resource covers recent applications towards the synthesis of heterocycles and also describes the details of the novel transformations in a didactic manner to motivate readers in search of new catalytic processes. The editors have included state-of-the-art strategies, including transition-metal reactions involving unsaturated systems (reactions of allenes, new gold(I)-catalyzed reactions, and Prins reaction).

Additional chapters highlight the versatility of organopalladium chemistry dealing with carbonylative transformations, C-H activation reactions, coupling processes, and the control of the ambiphilic character of organopalladium species. Finally, the book discusses new reactions leading to heterocycles based on C-H activation processes catalysed by other metals (Rh, Ru, Co).

Written by an outstanding team of authors who are leading experts in organometallic chemistry and organic synthesis, the contents of this book are extremely helpful not only for chemists focused mainly on synthesis but also for those interested in reaction mechanisms involving transition metals.

Key Features

  • Helpfully organized by transformation type to stimulate the search for new synthetic processes
  • Thoroughly illustrated and written by global experts
  • Thoughtfully selected strategies chosen by the editors to exemplify the state-of-the-art of the subject, including transition-metal reactions involving unsaturated systems, organopalladium chemistry, and metal-catalyzed C-H activation

Readership

Researchers in organic synthesis, catalysis, natural product synthesis, & medicinal chemistry, in academia & industry. Secondary market, advanced students

Table of Contents

  1. New Transition Metal-Catalyzed Annulations Involving Allenes
    2. Novel Gold(I)-Catalyzed Cyclization Reactions Towards the Synthesis of Aza- and Oxaheterocycles
    3. Iron-Catalyzed Prins Reactions Towards the Synthesis of Oxaheterocycles
    4. Synthesis of Heterocycles Through Transition Metal-Catalyzed Isomerization Involving Metathesis Reactions
    5. Synthesis of Heterocycles by Palladium-Catalyzed Carbonylative Reactions
    6. Synthesis of Heterocycles by Palladium-Catalyzed Arylation and Alkenylation of C(sp3)-H Bonds
    7. Palladium-Catalyzed C-H Activation of Aliphatic Amines to Give Strained Heterocycles
    8. Synthesis of Heterocycles by Palladium-Catalyzed Coupling Reactions Involving Tosylhydrazones
    9. Controlling the Selectivity in Intramolecular Palladium-Catalyzed Cyclization Reactions Towards the Synthesis of Heterocycles
    10. Synthesis of Heterocycles by C-H Bond Functionalization Based on Transition- Metal Carbene Migratory Insertion
    11.New Alkyne Annulations Catalyzed by Transition Metals (Ru, Co, …) Towards the Synthesis of Heterocycles

Details

No. of pages:
375
Language:
English
Copyright:
© Academic Press 2018
Published:
Imprint:
Academic Press
Paperback ISBN:
9780128116517

About the Editor

Daniel Sole

Dr. Daniel Sole is a Professor in the Department of Organic Chemistry at the University of Barcelona, Spain. He is an expert in in the development of transition metal--‐catalyzed transformations towards the synthesis of new species (especially heterocyclic compounds), as well as in the study of the reaction mechanisms and bonding situation of key intermediates involved in these transformations. He has published several papers on palladium-catalyzed C–H activation, α-arylation, and palladium-catalyzed nucleophilic addition reactions

Affiliations and Expertise

Professor Department of Organic Chemistry, University of Barcelona, Spain

Israel Fernandez

Dr. Israel Fernandez is a Professor in the Chemistry Department at Complutense University of Madrid, Madrid, Spain. His expertise is in the development of transition metal--‐ catalyzed transformations towards the synthesis of new species (especially heterocyclic compounds), as well as in the study of the reaction mechanisms and bonding situation of key intermediates involved in these transformations. Together with Dr. Daniel Sole he has published several papers on palladium-catalyzed C–H activation, α-arylation and palladium-catalyzed nucleophilic addition reactions.

Affiliations and Expertise

Department of Organic Chemistry, Complutense University of Madrid, Madrid, Spain