Advances in Transition-Metal Mediated Heterocyclic Synthesis provides an overview of recent catalytic reactions involving transition metals (palladium, platinum, rhodium, ruthenium, copper, iron and gold) to produce heterocyclic compounds. The book is organized according to the type of transformation used to achieve the synthesis of the Heterocyclic systems (mainly aza- and oxa-heterocycles). As such, it covers recent applications on the synthesis of heterocycles, also describing the details of the novel transformations in a didactic manner to motivate readers in search of new catalytic processes. The editors have included state-of-the-art strategies, including transition-metal reactions involving unsaturated systems (reactions of allenes, new gold(I)-catalyzed reactions, and Prins reaction).
Chapters highlight the versatility of organopalladium chemistry dealing with carbonylative transformations, C-H activation reactions, coupling processes, and the control of the ambiphilic character of organopalladium species. Finally, the book discusses new reactions leading to heterocycles based on C-H activation processes catalyzed by other metals (Rh, Ru, Co).
Written by an outstanding team of authors who are leading experts in organometallic chemistry and organic synthesis, the contents of this book are extremely helpful, not only for chemists mainly focused on synthesis, but also for those interested in reaction mechanisms involving transition metals.
- Helpfully organized by transformation type to stimulate the search for new synthetic processes
- Completely illustrated and written by global experts
- Includes thoughtfully selected strategies chosen by the editors to exemplify the state-of-the-art of the subject, including transition-metal reactions involving unsaturated systems, organopalladium chemistry, and metal-catalyzed C-H activation
Researchers in organic synthesis, catalysis, natural product synthesis, & medicinal chemistry, in academia & industry. Secondary market, advanced students
- New Transition Metal-Catalyzed Annulations Involving Allenes
2. Novel Gold(I)-Catalyzed Cyclization Reactions Towards the Synthesis of Aza- and Oxaheterocycles
3. Iron-Catalyzed Prins Reactions Towards the Synthesis of Oxaheterocycles
4. Synthesis of Heterocycles Through Transition Metal-Catalyzed Isomerization Involving Metathesis Reactions
5. Synthesis of Heterocycles by Palladium-Catalyzed Carbonylative Reactions
6. Synthesis of Heterocycles by Palladium-Catalyzed Arylation and Alkenylation of C(sp3)-H Bonds
7. Palladium-Catalyzed C-H Activation of Aliphatic Amines to Give Strained Heterocycles
8. Synthesis of Heterocycles by Palladium-Catalyzed Coupling Reactions Involving Tosylhydrazones
9. Controlling the Selectivity in Intramolecular Palladium-Catalyzed Cyclization Reactions Towards the Synthesis of Heterocycles
10. Synthesis of Heterocycles by C-H Bond Functionalization Based on Transition- Metal Carbene Migratory Insertion
11. New Alkyne Annulations Catalyzed by Transition Metals (Ru, Co, …) Towards the Synthesis of Heterocycles
- No. of pages:
- © Academic Press 2018
- 1st June 2018
- Academic Press
- Paperback ISBN:
Dr. Daniel Sole is a Professor in the Department of Organic Chemistry at the University of Barcelona, Spain. He is an expert in in the development of transition metal--‐catalyzed transformations towards the synthesis of new species (especially heterocyclic compounds), as well as in the study of the reaction mechanisms and bonding situation of key intermediates involved in these transformations. He has published several papers on palladium-catalyzed C–H activation, α-arylation, and palladium-catalyzed nucleophilic addition reactions
Professor, Department of Organic Chemistry, University of Barcelona, Spain
Dr. Israel Fernandez is a Professor in the Chemistry Department at Complutense University of Madrid, Madrid, Spain. His expertise is in the development of transition metal--‐ catalyzed transformations towards the synthesis of new species (especially heterocyclic compounds), as well as in the study of the reaction mechanisms and bonding situation of key intermediates involved in these transformations. Together with Dr. Daniel Sole he has published several papers on palladium-catalyzed C–H activation, α-arylation and palladium-catalyzed nucleophilic addition reactions.
Department of Organic Chemistry, Complutense University of Madrid, Madrid, Spain