Advances in Radiation Biology

Advances in Radiation Biology

Volume 5

1st Edition - January 1, 1975

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  • Editors: John T. Lett, Howard Adler
  • eBook ISBN: 9781483281933

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Advances in Radiation Biology, Volume 5 focuses on the various phases of development in radiation biology. This book discusses the radiobiological implications of statistical variations in energy deposition by ionizing radiations; fundamental physics of energy deposition; and radiological assessment of nuclear power stations. The environmental transport of released radionuclides; effects of continuous irradiation on animal populations; and radiation-induced life-shortening and premature aging are also deliberated. This text likewise covers the production of radiation damage in a heterogeneous system; radical identification by EPR; redistribution of cells through the division cycle; and iso-effect formulas. This publication is valuable to radiation biologists, including those interested in radiobiology.

Table of Contents

  • Contributors

    Contents of other Volumes

    The Radiobiological Implications of Statistical Variations in Energy Deposition by Ionizing Radiations

    I. Introduction

    II. Traditional Approaches to Microdosimetry

    III. Fundamental Physics of Energy Deposition

    IV. Importance of Statistical Processes

    V. An Illustration of Possible Radiobiological Interpretation

    VI. Modeling Based on Microdosimetric Concepts


    Radiological Assessment of Nuclear Power Stations

    I. Introduction

    II. Radioactivity Releases from Nuclear Power Stations

    III. Environmental Transport of Released Radionuclides

    IV. Estimation of Radiation Dose

    V. Assessment of the Dose Estimates

    VI. Future Developments


    EfFects of Continuous Irradiation on Animal Populations

    I. Introduction

    II. General Designs of Field Studies

    III. Dosimetry

    IV. Effects of Continuous Irradiation on Animal Populations

    V. Discussion


    Radiation-Induced Life-Shortening and Premature Aging

    I. Introduction

    II. Definitions

    III. Historical Basis for an Association of Radiation-Induced Life-Shortening and Natural Senescence

    IV. Evidence against the Hypothesis That Radiation-Induced Life-Shortening and Pathology are Related to Natural Senescence

    V. Conclusions


    Molecular Mechanisms of Radiation-Induced Damage to Nucleic Acids

    I. Introduction

    II. Production of Radiation Damage in a Heterogeneous System

    III. Simulation of In Vivo Radiation Damage Using In Vitro Model Systems

    IV. Irradiation of Solid Materials

    V. Frozen Solutions

    VI. Aqueous Solutions

    VII. Radical Identification by EPR

    VIII. Radiation Products of the Purine and Pyrimidine Bases

    IX. Strand Breaks

    X. Modifications of Radiation Damage Caused by Macromolecular Structure

    XI. Effects of Other Free Radicals on DNA Constituents

    XII. Methods of Examining Direct Effects in Aqueous Systems

    XIII. Radiation Modifiers



    The Four R's of Radiotherapy

    I. Introduction

    II. Repair of Sublethal Injury

    III. Reoxygenation

    IV. Redistribution of Cells through the Division Cycle

    V. Regeneration

    VI. Iso-Effect Formulas


    Subject Index

Product details

  • No. of pages: 288
  • Language: English
  • Copyright: © Academic Press 1975
  • Published: January 1, 1975
  • Imprint: Academic Press
  • eBook ISBN: 9781483281933

About the Editors

John T. Lett

Howard Adler

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