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Advances in Radiation Biology - 1st Edition - ISBN: 9780120354047, 9781483281940

Advances in Radiation Biology

1st Edition

Volume 4

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Editors: John T. Lett Howard Adler Max Zelle
eBook ISBN: 9781483281940
Imprint: Academic Press
Published Date: 28th February 1974
Page Count: 448
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Advances in Radiation Biology, Volume 4 provides wide-ranging analyses of progress in the various phases of radiation biology. This book discusses the repair processes for photochemical damage in mammalian cells; S-phase recovery or postreplication repair; enzymes involved in the repair of DNA; and reinsertion of nucleotides. The mutation induction in mice; dominant visible mutations; experimental radiation carcinogenesis; and dose-effect relationships are also deliberated. This text likewise covers the toxicology of plutonium; effects of ionizing radiation on terrestrial plant communities; and radiation sensitivities of plant communities. This publication is beneficial to radiation biologists, as well as students and researchers conducting work on radiobiology.

Table of Contents



Contents of Other Volumes

Repair Processes for Photochemical Damage in Mammalian Cells

I. Introduction

II. Excision Repair

III. S-Phase Recovery or Postreplication Repair

IV. Photoreactivation

V. Some Implications and Conclusions


Enzymes Involved in the Repair of DNA

I. Introduction

II. Incision Step

III. Excision Mechanisms

IV. Pre-Reinsertion Mechanisms

V. Reinsertion of Nucleotides

VI. Sealing of the Final Phosphodiester Bond

VII. Conclusions


Mutation Induction in Mice

I. Introduction

II. Gametogenesis

III. Specific Locus Mutations

IV. Dominant Visible Mutations

V. Skeletal Mutations

VI. Histocompatibility Mutations

VII. Recessive Visible Mutations

VIII. Recessive Lethal Mutations

IX. Summary


Experimental Radiation Carcinogenesis

I. Introduction

II. General Considerations on the Significance of Animal Data for Radiation Carcinogenesis

III. Tissues at Risk

IV. Dose-Effect Relationships

V. Relative Biological Effectiveness (RBE)

VI. Effect of Dose Rate

VII. Dependence of Sensitivity on Age

VIII. Differences in Sensitivity between Strains and between Species

IX. Summary


Toxicology of Plutonium

I. Introduction

II. Properties of Plutonium of Biomedical Interest

III. Disposition of Plutonium in the Body

IV. Biological Effects

V. Countermeasures for Plutonium Contamination

VI. Concluding Comments


Effects of Ionizing Radiation on Terrestrial Plant Communities

I. Introduction

II. Methods of Study

III. Types of Effects Observed

IV. Recovery of Radiation-Damaged Plant Communities

V. Radiation Sensitivities of Plant Communities

VI. Concluding Remarks


The Breakage-and-Reunion Theory and the Exchange Theory for Chromosomal Aberrations Induced by Ionizing Radiations: A Short History

I. Introduction

II. Chromosomal Aberrations

III. The Development of Breakage-and-Reunion Theory

IV. The Exchange Theory

V. Implications of the Exchange Theory for Aberration Development

VI. Some Questions and Objections

VII. Further Evidence for and against the Exchange Theory

VIII. Conclusions


Author Index

Subject Index


No. of pages:
© Academic Press 1974
28th February 1974
Academic Press
eBook ISBN:

About the Editors

John T. Lett

Howard Adler

Max Zelle

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