Advances in Metabolic Disorders - 1st Edition - ISBN: 9781483199436, 9781483224466

Advances in Metabolic Disorders

1st Edition

Volume 3

Editors: Rachmiel Levine Rolf Luft
eBook ISBN: 9781483224466
Imprint: Academic Press
Published Date: 1st January 1968
Page Count: 348
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Description

Advances in Metabolic Disorders, Volume 3 is a compendium of papers that discusses the regulation of ketogenesis, spontaneous diabetes, ethanol-induced hypoglycemia, and hormonal syndromes associated with neoplasia. One paper discusses the primary role of long-chain fatty acids in synergistically controlling enhanced ketogenesis and gluconeogenesis found in the liver at the cellular level. Another paper notes that in rodent experiments, when hypertrophy and hyperplasia are maintained without exhaustion or degeneration and are sufficient in degree, a new equilibrium emerges leading to near-normalization or compensated diabetes. The opposite occurs when hypertrophy and hyperplasia are limited in degree or in duration: decompensation occurs, diabetes progresses. Some papers describe metabolic disorders of the ovary, erythropoietin, and thyroid diseases. One paper analyzes the pathological conditions arising from impairments of the hypothalamic-pituitary-ovarian-uterine axis that can cause disturbances in normal reproduction Another paper investigates if a competitive relationship exists between thyrotropin (TSH) and long-acting thyroid stimulator (LATS). In vivo and in vitro studies show that the effect of LATS are associated mainly with a delayed onset of action. Biochemists, micro-biologists, endocrinologists, and researchers dealing with microchemistry, bacteriology and immunology will find this collection valuable.

Table of Contents


Contributors


Preface


Contents of Previous Volumes


Ketogenesis and its Regulation


I. Introduction


II. Biochemistry of the Ketone Bodies


III. Physiological Considerations in Ketone Formation


IV. The Practicability of Alloxan Diabetes as a Model for Studying Ketogenesis


V. Hepatocellular Regulation of Ketone Body Formation


VI. Relation between Ketogenesis and Gluconeogenesis


VII. Concluding Comment


References


Spontaneous Diabetes and/or Obesity in Laboratory Redents


I. Introduction


II. Syndromes in Mice (Mus musculus)


III. Syndromes in Other Species


IV. Features Common to Several Syndromes


V. Conclusions


References


Addendum


Ethanol-Induced Hypoglycemia


I. Introduction


II. Characteristics of Ethanol-lnduced Hypoglycemia


III. Pathogenesis of Ethanol-lnduced Hypoglycemia


References


Hormonal Syndromes Associated with Neoplasia


I. Introduction


II. Hypoglycemia


III. Hyperthyroidism


IV. Precocious Puberty and Inappropriate Gonadotropin Excretion


V. Hyponatremia


VI. Erythrocytosis


VII. Hypercalcemia


VIII. Ectopic ACTH Syndrome


IX. Polyfunctional Neoplasms


X. Humoral Syndromes


XI. Summary


References


Meabolic Disorders of the Ovary


I. Introduction


II. Physiology


III. Abnormal Ovarian Metabolism


References


The Nature and Significance of the Long-Acting Thyroid Stimulator


I. Introduction


II. Nature of LATS


III. Significance of LATS


References


Thyroid Autoantibo

Details

No. of pages:
348
Language:
English
Copyright:
© Academic Press 1968
Published:
Imprint:
Academic Press
eBook ISBN:
9781483224466

About the Editor

Rachmiel Levine

Rolf Luft

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