Advances in Metabolic Disorders - 1st Edition - ISBN: 9780120273065, 9781483215488

Advances in Metabolic Disorders

1st Edition

Volume 6

Editors: Rachmiel Levine Rolf Luft
eBook ISBN: 9781483215488
Imprint: Academic Press
Published Date: 28th November 1972
Page Count: 250
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Advances in Metabolic Disorders, Volume 6 covers the developments in the study of metabolic disorders. The book discusses the role of the skin in carbohydrate metabolism; the transmission of Alloxan diabetes and other diabetogenic influences; and the association between glucagon levels and diabetes mellitus. The text also describes the recent contributions to the study of diabetic angiopathy and neuropathy; the disorders due to enzyme defects in the red blood cell; and the pineal gland as a neuroendocrine inducer. The basic aspects of the biology and physiology of calcitonin in relation to its hitherto acknowledged significance in clinical metabolic disorders are also considered. Endocrinologists, biochemists, pharmacologists, physicians, physiologists and medical students will find the book invaluable.

Table of Contents


Contents of Previous Volumes

The Role of the Skin in Carbohydrate Metabolism

I. Introduction

II. Properties of Skin

III. The Role of the Dermis in Glucose Homeostasis

IV. Carbohydrate Metabolism of the Epidermis

V. Sources of Energy in the Epidermis

VI. Glucose/Lactate Balance in the Intact Animal

VII. The Skin as an Indicator of Impaired Carbohydrate Metabolism

VIII. Concluding Remarks



On the Transmission of Alloxan Diabetes and Other Diabetogenic Influences

I. Introduction—The Enigma of the Genetics of Human Diabetes

II. The Question of Spontaneous and Experimentally Induced Diabetes in Animals

III. Studies on Transmission of Experimental Diabetes Mellitus

IV. Induction and Transmission of Latent Diabetes

V. Pregnancy in Animals with Induced Carbohydrate Intolerance

VI. Plasma Insulin in Animals with Induced Diabetes

VII. Beta Cell Histology of Rats with Induced and Transmitted Diabetes

VIII. Interpretation of the Data


Glucagon and Diabetes Mellitus

I. Introduction

II. Normal Alpha Cell Function

III. Diabetic Ketoacidosis


Recent Contributions to the Study of Diabetic Angiopathy and Neuropathy

I. General Characteristics of Diabetic Angiopathy and Neuropathy

II. The Eye

III. The Kidney

IV. The Heart

V. The Extremities

VI. Capillary Resistance and Capillary Permeability

VII. Diabetic Neuropathy

VIII. Pathogenesis of Diabetic Angiopathy

IX. Pathogenesis of Diabetic Neuropathy

X. Prophylaxis and Therapy


Disorders Due to Enzyme Defects in the Red Blood Cell

I. General Considerations

II. Defects of the Embden-Meyerhof Pathway

III. Deficiencies in the Hexose Monophosphate and Related Pathways

IV. Other Enzyme Defects Associated with Hematologic Disease


The Pineal Gland—A Neuroendocrine Transducer

I. Introduction

II. Effects on the Reproductive System

III. Effects on the Adrenal Glands

IV. Effects on the Thyroid Gland

V. Effects on Growth and Growth Hormone

VI. Nonendocrine Effects

VII. Conclusions


Calcitonin in Metabolic Disorders

I. Calcitonin in the Scheme of Calcium Homeostasis

II. Nature of Calcitonin and Its Action

III. Clinical Considerations

IV. Summary


Author Index

Subject Index


No. of pages:
© Academic Press 1972
Academic Press
eBook ISBN:

About the Editor

Rachmiel Levine

Rolf Luft

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