Advances in Metabolic Disorders

Advances in Metabolic Disorders

Volume 6

1st Edition - November 28, 1972

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  • Editors: Rachmiel Levine, Rolf Luft
  • eBook ISBN: 9781483215488

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Advances in Metabolic Disorders, Volume 6 covers the developments in the study of metabolic disorders. The book discusses the role of the skin in carbohydrate metabolism; the transmission of Alloxan diabetes and other diabetogenic influences; and the association between glucagon levels and diabetes mellitus. The text also describes the recent contributions to the study of diabetic angiopathy and neuropathy; the disorders due to enzyme defects in the red blood cell; and the pineal gland as a neuroendocrine inducer. The basic aspects of the biology and physiology of calcitonin in relation to its hitherto acknowledged significance in clinical metabolic disorders are also considered. Endocrinologists, biochemists, pharmacologists, physicians, physiologists and medical students will find the book invaluable.

Table of Contents

  • Contributors

    Contents of Previous Volumes

    The Role of the Skin in Carbohydrate Metabolism

    I. Introduction

    II. Properties of Skin

    III. The Role of the Dermis in Glucose Homeostasis

    IV. Carbohydrate Metabolism of the Epidermis

    V. Sources of Energy in the Epidermis

    VI. Glucose/Lactate Balance in the Intact Animal

    VII. The Skin as an Indicator of Impaired Carbohydrate Metabolism

    VIII. Concluding Remarks



    On the Transmission of Alloxan Diabetes and Other Diabetogenic Influences

    I. Introduction—The Enigma of the Genetics of Human Diabetes

    II. The Question of Spontaneous and Experimentally Induced Diabetes in Animals

    III. Studies on Transmission of Experimental Diabetes Mellitus

    IV. Induction and Transmission of Latent Diabetes

    V. Pregnancy in Animals with Induced Carbohydrate Intolerance

    VI. Plasma Insulin in Animals with Induced Diabetes

    VII. Beta Cell Histology of Rats with Induced and Transmitted Diabetes

    VIII. Interpretation of the Data


    Glucagon and Diabetes Mellitus

    I. Introduction

    II. Normal Alpha Cell Function

    III. Diabetic Ketoacidosis


    Recent Contributions to the Study of Diabetic Angiopathy and Neuropathy

    I. General Characteristics of Diabetic Angiopathy and Neuropathy

    II. The Eye

    III. The Kidney

    IV. The Heart

    V. The Extremities

    VI. Capillary Resistance and Capillary Permeability

    VII. Diabetic Neuropathy

    VIII. Pathogenesis of Diabetic Angiopathy

    IX. Pathogenesis of Diabetic Neuropathy

    X. Prophylaxis and Therapy


    Disorders Due to Enzyme Defects in the Red Blood Cell

    I. General Considerations

    II. Defects of the Embden-Meyerhof Pathway

    III. Deficiencies in the Hexose Monophosphate and Related Pathways

    IV. Other Enzyme Defects Associated with Hematologic Disease


    The Pineal Gland—A Neuroendocrine Transducer

    I. Introduction

    II. Effects on the Reproductive System

    III. Effects on the Adrenal Glands

    IV. Effects on the Thyroid Gland

    V. Effects on Growth and Growth Hormone

    VI. Nonendocrine Effects

    VII. Conclusions


    Calcitonin in Metabolic Disorders

    I. Calcitonin in the Scheme of Calcium Homeostasis

    II. Nature of Calcitonin and Its Action

    III. Clinical Considerations

    IV. Summary


    Author Index

    Subject Index

Product details

  • No. of pages: 250
  • Language: English
  • Copyright: © Academic Press 1972
  • Published: November 28, 1972
  • Imprint: Academic Press
  • eBook ISBN: 9781483215488

About the Editors

Rachmiel Levine

Rolf Luft

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