Advances in Lipid Research

1st Edition, Volume 6 - January 1, 1968
Editors: Rodolfo Paoletti, David Kritchevsky
Language: English
eBook ISBN:
9 7 8 - 1 - 4 8 3 2 - 2 4 4 5 - 9

Advances in Lipid Research, Volume 6 provides information pertinent to brain cholesterol and myelin lipids. This book reviews the various aspects of the physiology, chemistry, and… Read more

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Advances in Lipid Research, Volume 6 provides information pertinent to brain cholesterol and myelin lipids. This book reviews the various aspects of the physiology, chemistry, and biochemistry of lipids. Organized into seven chapters, this volume begins with an overview of the separation of lipoproteins and discusses lipid metabolism in microorganisms. This text then provides a discussion of lipid metabolism in mycoplasmas. Other chapters consider the various aspects of metabolism of the lipid quinones and explore the relationship between lipids and atherosclerosis as a continuing source of biochemical, medical, and nutritional interest. This book discusses as well a comparative aspect of the development of atherosclerosis and explains the chemistry of bile acids. The final chapter deals with the aspects of steroid separations as well as with regard to separation of other metabolites that may influence lipid metabolism. This book is a valuable resource for biologists, biochemists, scientists, and research workers.

List of Contributors

Preface

Contents of Previous Volumes

Practical Methods for Plasma Lipoprotein Analysis

I. Introduction

II. The Physicochemical Basis of Lipoprotein Fractionation

III. Methods Used in Lipoprotein Separations

IV. Practical Methods for Lipoprotein Analysis

V. Conclusions

References

The Lipids of Mycoplasma

I. Introduction

II. Lipid Composition and Cellular Location

III. The Nature of Mycoplasmal Lipids

IV. Lipid Nutrition of Mycoplasma

V. Biosynthesis of Lipids by Mycoplasma

VI. Metabolism of Lipids by Mycoplasma

VII. Functional Roles of Lipids in Mycoplasma

Note Added in Proof

References

Lipid Quinones

I. Introduction

II. General Considerations

III. Physical and Chemical Properties

IV. Procedures of Isolation

V. Quantitative Analysis

VI. Natural Occurrence and Distribution

VII. Synthesis and Biosynthesis

VIII. Relationship to Nutrition

IX. Metabolic Role of Lipid Quinones

References

Comparative Pathogenetic Patterns in Atherosclerosis

I. Introduction

II. Lipoprotein Accumulation in and Injury to Medial Smooth Muscle Cells

III. The Smooth Muscle Cell of the Artery Wall Responds by Proliferating, Migrating, and Modifying its Metabolism

IV. Smooth Muscle Cell Migration and Colonization Into or on Arterial Transplants or Prostheses

V. The Arterial Smooth Muscle Cell Produces Variable Quantities of Collagen, Elastin, Smooth Muscle Fibers, Ground Substance, and Basement Membrane

VI. Circulating Lipid-Filled Monocyte versus Lipoprotein Filtration in Atherogenesis

VII. The Role of Arterial Lipid Synthesis in the Development of Atherosclerosis in Certain Species

References

Chemistry and Metabolism of Bile Alcohols and Higher Bile Acids

I. Introduction

II. Separation and Analysis of Bile Alcohols and Higher Bile Acids

III. Chemistry of Bile Alcohols and Higher Bile Acids

IV. Biosynthesis and Metabolism of Bile Alcohols and Higher Bile Acids

V. Conclusion

References

Hydroxy Fatty Acid Metabolism in Brain

I. Background Information

II. Biosynthesis of the 2-Hydroxy Acids

III. Metabolism of 2-Hydroxy Acids

IV. Prostaglandins

V. Hydroxy Fatty Acids in Disease

References

Gas Phase Analytical Methods for the Study of Steroids

I. Introduction

II. The Practice of Gas Chromatography

III. Structure-Retention Time Relationships

IV. Separation Methods for Steroid Classes

V. Identification of Steroids by Mass Spectrometry

VI. Quantification

References

Author Index

Subject Index