Advances in Lipid Research

Advances in Lipid Research

1st Edition - January 1, 1965

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  • Editors: Rodolfo Paoletti, David Kritchevsky
  • eBook ISBN: 9781483224428

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Advances in Lipid Research, Volume 3 presents the analysis of human serum lipoproteins and emphasizes the possibilities inherent in the application of computer methods to such analyses. This book discusses the effects of various drugs on the other important component of the serum lipids, the phospholipids. Organized into six chapters, this volume begins with an overview of the possibility of a dehydrogenation toward the methyl group. This text then presents a detailed discussion of lipoprotein structure, metabolism, and catabolism. Other chapters consider some potentially significant revisions in lipoprotein procedure, including additions to the technology of lipoprotein analysis. This book discusses as well the chemistry and metabolism of plasma lipoprotein as related to physiological and disease states. The final chapter deals with the advances in methods of purification and studies of the properties and mode of action of lipases. This book is a valuable resource for organic chemists, neurochemists, and biochemists.

Table of Contents

  • Contributors to this Volume


    The Metabolism of Polyenoic Fatty Acids

    I. The Transformation of Oleic Acid into △5,8,11-C20-Trienoic Acid

    II. The Inconvertibility of One Type of Polyenoic Acid into Another

    III. The Behavior of the Isomers of Linoleic and Linolenic Acids

    IV. The Combustibility of the Polyenoic Acids

    Addendum: Preparation by Total Synthesis of Unsaturated, Especially Polyenoic, Fatty Acids


    The Analysis of Human Serum Lipoprotein Distributions

    I. Introduction and General Considerations of Human Serum Lipoprotein Analysis

    II. Some Unique Problems of Ultracentrifugal Lipoprotein Isolation and Flotation Analysis

    III. A Generalized Method for the Computer Analysis of Lipoprotein Distributions

    IV. Application of Computer Analysis to a Series of Adult Normal Males and Females

    V. Potential Improvements in the Computer Methodology for Lipoprotein Analysis


    Factors Affecting Lipoprotein Metabolism

    I. Introduction

    II. Physical and Chemical Properties of Plasma Lipoproteins

    III. Experimental Approach to Lipoprotein Structure

    IV. Biosynthesis of Plasma Lipoproteins

    V. Catabolism of Plasma Lipoproteins

    VI. Significance of Lipoproteins in Fat Transport

    VII. Concluding Remarks


    The Action of Drugs on Phospholipid Metabolism

    I. Introduction

    II. Excitants and Antidepressants

    III. Depressants

    IV. Glycosides

    V. Pharmacologically Active Phospholipids


    Brain Sterol Metabolism

    I. Introduction

    II. Distribution of Sterols in the Developing Brain

    III. Distribution of Cholesterol in the Adult Mammalian Brain

    IV. Brain Cholesterol Metabolism

    V. Brain Sterols: The Effects of Drugs

    VI. Brain Cholesterol: The Effects of Malnutrition

    VII. Brain Sterols: The Effects of Disease

    VIII. Conclusion



    I. Introduction

    II. Distribution of Lipases

    III. Methods of Determining Lipase Activity

    IV. Purification

    V. Substrate Specificity and Mode of Action

    VI. Factors Affecting the Velocity of Hydrolysis

    VII. Lipoprotein Lipase

    VIII. Summary


    Author Index

    Subject Index

Product details

  • No. of pages: 278
  • Language: English
  • Copyright: © Academic Press 1965
  • Published: January 1, 1965
  • Imprint: Academic Press
  • eBook ISBN: 9781483224428

About the Editors

Rodolfo Paoletti

David Kritchevsky

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