Advances in Lipid Research

Advances in Lipid Research

1st Edition - January 1, 1963

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  • Editors: Rodolfo Paoletti, David Kritchevsky
  • eBook ISBN: 9781483224404

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Advances in Lipid Research, Volume 1 provides information pertinent to the structure and behavior of lipids through sulfolipids. This book presents the advances on fat absorption and transport. Organized into 10 chapters, this volume begins with an overview of the methods for the analysis of glycerine mixtures that require the determination of the fatty acid composition of the whole mixture and of its component fraction. This text then examines lipids as molecules of biological interest having little or no solubility in water. Other chapters cover the advances in cholesterol metabolism, Vitamin E as it affects lipid metabolism, and a discussion on atherosclerosis. This book discusses as well all areas of lipid research ranging from physical chemistry to physiology and pathology. The final chapter deals with sulfolipid, which appears to be concentrated in the lamellar membranes of the chloroplasts of plants. This book is a valuable resource for physical chemists, biologists, and pathologists.

Table of Contents

  • Contributors


    The Structural Investigation of Natural Fats

    I. Introduction

    II. Determination of Fatty Acid Composition

    III. Determination of Glyceride Composition

    IV. Theories of Glyceride Structure

    V. Recent Investigations of Natural Fats

    VI. Conclusion


    Physical Structure and Behavior of Lipids and Lipid Enzymes

    I. Introduction

    II. Lipids in Water

    III. Lipid Water Interfacial Phenomena

    IV. Lipid Structures in Biological Material


    Recent Developments in the Mechanism of Fat Absorption

    I. Introduction

    II. Enzymatic Hydrolysis of Dietary Triglycerides

    III. The Penetration of the Mucosal Cell by Fats

    IV. Metabolism of Fats in the Intestinal Mucosa

    V. The Formation of Chylomicrons and their Passage into the Lymph


    The Clearing Factor Lipase and its Action in the Transport of Fatty Acids between the Blood and the Tissues

    I. Early Studies on the Clearing Factor Lipase

    II. Localization of the Clearing Factor Lipase

    III. The Role of Heparin in Clearing Factor Lipase Action

    IV. The Release of Clearing Factor Lipase by Compounds Other than Heparin

    V. The Specificity of the Clearing Factor Lipase

    VI. Inhibitors of the Clearing Factor Lipase in the Blood

    VII. Other Enzymes Released into Plasma by the Injection of Heparin

    VIII. The Presence of Clearing Factor Lipase in the Plasma without Heparin Injection

    IX. Variations in the Activity of Clearing Factor Lipase in the Tissues

    X. The Measurement of Clearing Factor Lipase

    XI. The Transport of Fatty Acids Between the Blood and the Tissues

    XII. The Role of Clearing Factor Lipase in Fat Transport

    XIII. Changes in the Activity of the Clearing Factor Lipase in Various Disease States

    XIV. Concluding Remarks


    Vitamin E and Lipid Metabolism

    I. Introduction

    II. Vitamin E as an Antioxidant

    III. Lipid Metabolism in Muscular Dystrophy

    IV. Vitamin E and Unsaturated Fatty Acids

    V. Vitamin E and Cholesterol Metabolism

    VI. Vitamin E and Enzyme Systems

    VII. Vitamin E and Ubiquinones

    VIII. Conclusion


    Atherosclerosis—Spontaneous and Induced

    I. Introduction

    II. Atherosclerosis in the Common Laboratory Animal Species

    III. Summary


    Chromatographic Investigations in Fatty Acid Biosynthesis

    I. Introduction

    II. Assay of Short Chain Precursors and Intermediates

    III. Chemical Forms of the Newly Synthesized Fatty Acids

    IV. Intensity of Synthesis of Individual Long Chain Fatty Acid

    V. Examination of the Carbon Atoms of the Synthesized Molecule of Fatty Acid

    VI. Conclusion


    Carnitine and Its Role in Fatty Acid Metabolism

    I. Nature of the Action of Carnitine on Fatty Acid Metabolism

    II. Carnitine Distribution, Synthesis, and Turnover

    III. Metabolism of Carnitine Derivatives

    IV. Significance of Carnitine and Acylcarnitine Derivatives in Physiological Processes

    V. Summary and Conclusions


    Present Status of Research on Catabolism and Excretion of Cholesterol

    I. Conversion of Cholesterol to Bile Acids

    II. Excretion of Cholesterol

    III. Conversion of Cholesterol to Pregnenolone


    The Plant Sulfolipid

    I. Terminology

    II. Occurrence

    III. Structure

    IV. Enzymatic Degradation

    V. Sulfolipid Phytosynthesis

    VI. Discussion


    Author Index

    Subject Index

Product details

  • No. of pages: 432
  • Language: English
  • Copyright: © Academic Press 1963
  • Published: January 1, 1963
  • Imprint: Academic Press
  • eBook ISBN: 9781483224404

About the Editors

Rodolfo Paoletti

David Kritchevsky

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