Advances in Lipid Research - 1st Edition - ISBN: 9780120249213, 9781483215426

Advances in Lipid Research, Volume 21

1st Edition

Editors: Rodolfo Paoletti David Kritchevsky
eBook ISBN: 9781483215426
Imprint: Academic Press
Published Date: 9th May 1985
Page Count: 504
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Table of Contents



Apolipoprotein B and Lipoprotein Metabolism

I. Introduction

II. Characterization of ApoB

III. Metabolism of ApoB in Lipoproteins

IV. Conclusions


Leukotrienes: Biosynthesis, Metabolism, and Analysis

I. Introduction

II. Mechanism of Leukotriene Biosynthesis

III. Metabolism of Leukotrienes

IV. Other Transformations of 5-Lipoxygenase

V. Leukotrienes Derived from 15-Lipoxygenase

VI. Control of Leukotriene Biosynthesis

VII. Analysis of Leukotrienes and Other Lipoxygenase Products

VIII. Concluding Remarks


Pharmacology of the Leukotrienes

I. Slow-Reacting Substance of Anaphylaxis and Leukotrienes

II. Nomenclature of Leukotrienes

III. Leukotrienes and SRS-A Release

IV. Pharmacological Activities of Leukotrienes

V. Leukotrienes in Inflammatory Reactions

VI. Pharmacological Control of Leukotriene Synthesis


Dietary Fat, Eicosanoids, and Immunity

I. Introduction

II. The Immune System and the Eicosanoids

III. Dietary Fat and the Immune Responses

IV. Conclusions


Gastrointestinal Digestion and Absorption of Lipid

I. Introduction

II. General Aspects of Intestinal Lipid Digestion and Absorption

III. Permeation of the Digested Fat into the Enterocyte

IV. The Intracellular Metabolism of the Absorbed Lipid

V. The Intracellular Assembly of Intestinal Lipoproteins

VI. Factors Affecting the Intestinal Chylomicron Secretion

VII. Regional Difference in Lymphatic Lipid Transport

VIII. Portal Transport of Long-Chain Fatty Acids

IX. Effect of Hormones on Intestinal Lipid Transport

X. Essential Fatty Acid-Deficient Rat

XI. Pluronic L-81 and Intestinal Lipid Transport

XII. Advances in the Past Two Decades


Lipids in the Structure and Function of Yeast Membrane

I. Introduction

II. Lipid Composition

III. Subcellular Localization

IV. Organization of Lipids

V. Factors that Influence Yeast Lipids

VI. Methods Employed to Alter Lipid Composition

VII. Lipids in Various Functions of Yeast

VIII. Lipids in the Structure of Yeast Membrane

IX. Conclusion


The in Vitro Biosynthesis of Carotenoids

I. Introduction

II. Structure and Nomenclature

III. Biosynthesis

IV. Preparation and Purification of Carotenogenic Cell Extracts

V. Assays of Carotenogenic Activities

VI. Properties of Carotenogenic Enzyme Preparations

VII. Regulation of Carotenoid Biosynthesis

VIII. Intracellular Distribution of Carotenogenic Enzymes

IX. Conclusions and Future Studies


Functional and Orientational Features of Protein Molecules in Reconstituted Lipid Membranes

I. Introduction

II. Methods Used for Reconstitution

III. Reconstitution of Transmembrane Integral Proteins and Complexes

IV. Reconstitution of Endoproteins

V. Proteoliposomes with More than One Reconstituted Protein or Complex

VI. In Vitro Assays of Incorporation of Mitochondrial Soluble Proteins into Liposomes

VII. General and Concluding Remarks

VIII. Appendix: Abbreviations


Author Index

Subject Index

Contents of Previous Volumes


Advances in Lipid Research, Volume 21 covers several significant and emerging areas in lipid metabolism, including apolipoprotein metabolism and leukotrienes. This book discusses the role of fat in the functioning of the immune system.

Organized into eight chapters, this volume begins with an overview of the metabolism of apolipoprotein B, which is the principal protein of chylomicrons, very low density, and low density lipoprotein. This text then describes the metabolism, biosynthesis, and pharmacology of leukotrienes. Other chapters consider the relation of lipids to immunology and explain the roles played by lipids in the structure and function of yeast membrane. This book discusses as well the general importance in the plant kingdom and the place of some carotenoids in human biology. The final chapter deals with the influence of proteins on configuration and function of reconstituted lipid membranes.

This book is a valuable resource for biologists, chemists, biochemists, scientists, and research workers.


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© Academic Press 1985
Academic Press
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About the Editors

Rodolfo Paoletti Editor

David Kritchevsky Editor