Advances in Lipid Research

Advances in Lipid Research

1st Edition - May 9, 1985

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  • Editors: Rodolfo Paoletti, David Kritchevsky
  • eBook ISBN: 9781483215426

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Advances in Lipid Research, Volume 21 covers several significant and emerging areas in lipid metabolism, including apolipoprotein metabolism and leukotrienes. This book discusses the role of fat in the functioning of the immune system. Organized into eight chapters, this volume begins with an overview of the metabolism of apolipoprotein B, which is the principal protein of chylomicrons, very low density, and low density lipoprotein. This text then describes the metabolism, biosynthesis, and pharmacology of leukotrienes. Other chapters consider the relation of lipids to immunology and explain the roles played by lipids in the structure and function of yeast membrane. This book discusses as well the general importance in the plant kingdom and the place of some carotenoids in human biology. The final chapter deals with the influence of proteins on configuration and function of reconstituted lipid membranes. This book is a valuable resource for biologists, chemists, biochemists, scientists, and research workers.

Table of Contents

  • Contributors


    Apolipoprotein B and Lipoprotein Metabolism

    I. Introduction

    II. Characterization of ApoB

    III. Metabolism of ApoB in Lipoproteins

    IV. Conclusions


    Leukotrienes: Biosynthesis, Metabolism, and Analysis

    I. Introduction

    II. Mechanism of Leukotriene Biosynthesis

    III. Metabolism of Leukotrienes

    IV. Other Transformations of 5-Lipoxygenase

    V. Leukotrienes Derived from 15-Lipoxygenase

    VI. Control of Leukotriene Biosynthesis

    VII. Analysis of Leukotrienes and Other Lipoxygenase Products

    VIII. Concluding Remarks


    Pharmacology of the Leukotrienes

    I. Slow-Reacting Substance of Anaphylaxis and Leukotrienes

    II. Nomenclature of Leukotrienes

    III. Leukotrienes and SRS-A Release

    IV. Pharmacological Activities of Leukotrienes

    V. Leukotrienes in Inflammatory Reactions

    VI. Pharmacological Control of Leukotriene Synthesis


    Dietary Fat, Eicosanoids, and Immunity

    I. Introduction

    II. The Immune System and the Eicosanoids

    III. Dietary Fat and the Immune Responses

    IV. Conclusions


    Gastrointestinal Digestion and Absorption of Lipid

    I. Introduction

    II. General Aspects of Intestinal Lipid Digestion and Absorption

    III. Permeation of the Digested Fat into the Enterocyte

    IV. The Intracellular Metabolism of the Absorbed Lipid

    V. The Intracellular Assembly of Intestinal Lipoproteins

    VI. Factors Affecting the Intestinal Chylomicron Secretion

    VII. Regional Difference in Lymphatic Lipid Transport

    VIII. Portal Transport of Long-Chain Fatty Acids

    IX. Effect of Hormones on Intestinal Lipid Transport

    X. Essential Fatty Acid-Deficient Rat

    XI. Pluronic L-81 and Intestinal Lipid Transport

    XII. Advances in the Past Two Decades


    Lipids in the Structure and Function of Yeast Membrane

    I. Introduction

    II. Lipid Composition

    III. Subcellular Localization

    IV. Organization of Lipids

    V. Factors that Influence Yeast Lipids

    VI. Methods Employed to Alter Lipid Composition

    VII. Lipids in Various Functions of Yeast

    VIII. Lipids in the Structure of Yeast Membrane

    IX. Conclusion


    The in Vitro Biosynthesis of Carotenoids

    I. Introduction

    II. Structure and Nomenclature

    III. Biosynthesis

    IV. Preparation and Purification of Carotenogenic Cell Extracts

    V. Assays of Carotenogenic Activities

    VI. Properties of Carotenogenic Enzyme Preparations

    VII. Regulation of Carotenoid Biosynthesis

    VIII. Intracellular Distribution of Carotenogenic Enzymes

    IX. Conclusions and Future Studies


    Functional and Orientational Features of Protein Molecules in Reconstituted Lipid Membranes

    I. Introduction

    II. Methods Used for Reconstitution

    III. Reconstitution of Transmembrane Integral Proteins and Complexes

    IV. Reconstitution of Endoproteins

    V. Proteoliposomes with More than One Reconstituted Protein or Complex

    VI. In Vitro Assays of Incorporation of Mitochondrial Soluble Proteins into Liposomes

    VII. General and Concluding Remarks

    VIII. Appendix: Abbreviations


    Author Index

    Subject Index

    Contents of Previous Volumes

Product details

  • No. of pages: 504
  • Language: English
  • Copyright: © Academic Press 1985
  • Published: May 9, 1985
  • Imprint: Academic Press
  • eBook ISBN: 9781483215426

About the Editors

Rodolfo Paoletti

David Kritchevsky

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