Advances in Lipid Research

Advances in Lipid Research

1st Edition - December 28, 1982

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  • Editors: Rodolfo Paoletti, David Kritchevsky
  • eBook ISBN: 9781483215419

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Advances in Lipid Research, Volume 19 is a seven-chapter text that covers the physical and biological aspects of lipid metabolism. The first chapter deals with the interactions between circulating lipids and lipid proteins and the arterial tissue matrix. The subsequent chapter discusses the apolipoprotein C metabolism, the roles of lecithin-cholesterol acyltransferase and cholesterol ester transfer protein in intravascular cholesterol transport. Other chapters explore the significance of bile acid biosynthesis for cholesterol homeostasis, the metabolism of phosphatidylserine, and gas chromatographic and mass spectrometry analysis of prostanoids. The last chapter considers the role of dietary fiber in health and disease. This book is of great value to lipid and enzyme chemists, biochemists, and researchers.

Table of Contents

  • List of Contributors


    The Interaction of Lipids and Lipoproteins with the Intercellular Matrix of Arterial Tissue: Its Possible Role in Atherogenesis

    I. Introduction

    II. Collagen

    III. Elastin

    IV. Glycosaminoglycans and Proteoglycans

    V. The Interactions of Glycoproteins of the Arterial Extracellular Matrix with Lipids and Lipoproteins

    VI. The Possible Effect of the Extracellular Matrix on Lipoprotein Movement through the Arterial Intima-Media

    VII. Conclusion


    Apolipoprotein C Metabolism in Man

    I. Introduction

    II. Methodology

    III. Structure-Function Relationships

    IV. Metabolism of C Apolipoproteins

    V. Measurements of C Apolipoprotein Kinetics in Man


    Lecithin: Cholesterol Acyltransferase and Intravascular Cholesterol Transport

    I. Introduction

    II. LCATase Characterization

    III. LCATase Reaction with Plasma Lipoproteins

    IV. Cholesteryl Ester Transfer Protein

    V. LCATase and Cellular Cholesterol Homeostasis

    VI. LCATase, Cholesteryl Ester Transfer Protein, and Intravascular Cholesterol Transport: Conclusions


    Development of Bile Acid Biogenesis and Its Significance in Cholesterol Homeostasis

    I. Introduction

    II. Development of Bile Acid Pool in Animals and Man

    III. Cholesterol and Bile Acid Metabolism in Fetal and Neonatal Liver

    IV. The Significance of Bile Acids and Sterols in Meconium

    V. Role of Endocrine Factors in the Development of Bile Acid Biogenesis

    VI. Stimulation of Bile Acid Biogenesis During Development as a Means of Improving Cholesterol Handling in Adult Life

    VII. Conclusions


    Biosynthesis and Transport of Phosphatidylserine in the Cell

    I. Introduction

    II. Net Synthesis of Phosphatidylserine

    III. Base Exchange Reaction

    IV. ATP-Dependent Phosphatidylserine Formation

    V. Decarboxylation of Phosphatidylserine

    VI. Transport of Phosphatidylserine

    VII. Conclusions


    Analysis of Prostanoids by GC/MS Measurement

    I. Introduction

    II. Gas Chromatography

    III. Mass Spectrometry

    IV. Derivatization of Prostanoids for GC/MS Measurement

    V. Computer Technology for GC/MS Measurements

    VI. Characteristics of GC/MS and RIA Analysis

    VII. Summary


    Morphological Aspects of Dietary Fibers in the Intestine

    I. Introduction

    II. Materials and Methods

    III. Results

    IV. Discussion


    Author Index

    Subject Index

    Contents of Previous Volumes

Product details

  • No. of pages: 270
  • Language: English
  • Copyright: © Academic Press 1982
  • Published: December 28, 1982
  • Imprint: Academic Press
  • eBook ISBN: 9781483215419

About the Editors

Rodolfo Paoletti

David Kritchevsky

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