Advances in Lipid Research - 1st Edition - ISBN: 9780120249121, 9781483215341

Advances in Lipid Research, Volume 12

1st Edition

Editors: Rodolfo Paoletti David Kritchevsky
eBook ISBN: 9781483215341
Imprint: Academic Press
Published Date: 28th October 1974
Page Count: 436
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Table of Contents


List of Contributors


Preface


Contents of Previous Volumes


The Relationship Between Plasma and Tissue Lipids in Human Atherosclerosis


I. Introduction


II. Relationship Between the Chemical and Morphological Characteristics of Lipid in Human Aortic Intima


III. Concentration of Plasma LD-Lipoprotein in Normal Intima and Lesions


IV. Quantitative Relationship Between Plasma Constituents in Intima


V. Relationship Between LD-Lipoprotein and the Lipid "Deposited" in Intima


VI. Conclusions


References


Lipid Metabolism in Cultured Cells


I. Introduction


II. Methodology


III. Fatty Acids


IV. Glycerides


V. Sterols


VI. Phospholipids


VII. Lipid Ethers


VIII. Studies of Drugs and Inhibitors of Lipid Metabolism in Cultured Cells


IX. Studies of Lipids in Differentiated Cells in Culture


X. Use of Cell Cultures for the Study of Lipidoses


XI. Comparison of Lipid Metabolism in Normal and Tumor Cells in Culture


XII. Summary and Conclusions


References


Effect of Diet on Activity of Enzymes Involved in Fatty Acid and Cholesterol Synthesis


I. Introduction


II. Dietary Adaptation of Specific Enzymes Involved in Fatty Acid and Cholesterol Synthesis


III. Overview


References


Role of Phospholipids in Transport and Enzymic Reactions


I. Introduction


II. Criteria for Establishing and Determining the Role of Lipids in Biological Processes


III. Nonspecific Role of Lipids in Biological Processes


IV. Effect of Membrane Fluidity and Lipid Phase Transitions on Functioning of Membrane-Bound Proteins


V. Specific Role of Lipids


VI. Partially Cha


Description

Advances in Lipid Research, Volume 12 is a seven-chapter text that focuses on the significant progress in lipid metabolism.

The opening chapter reviews the relationships between plasma and tissue lipids and atherosclerosis. Understanding the dynamics of exchange of plasma lipoproteins with aortic tissue is the basis of understanding the etiology of this disease and the approaches to therapy. The succeeding chapters describe the phases of lipid metabolism in cultured cells and the influences of various dietary components on the specific enzymes of fatty acid and cholesterol biogenesis. Other chapters discuss the role of phospholipids in transport and enzymic reactions, membrane fluidity, aspects of lipid-protein interactions, and the physiologic role of thyroid lipids. The closing chapters explore the chemistry and biological function of glycosyl glycerides, as well as the physiopathology of the biguanidines, a class of oral hypoglycemic agents.

This book will prove useful to lipid chemists, biochemists, and researchers.


Details

No. of pages:
436
Language:
English
Copyright:
© Academic Press 1974
Published:
Imprint:
Academic Press
eBook ISBN:
9781483215341

Ratings and Reviews


About the Editors

Rodolfo Paoletti Editor

David Kritchevsky Editor