Advances in Immunopharmacology - 1st Edition - ISBN: 9780080263847, 9781483145396

Advances in Immunopharmacology

1st Edition

Proceedings of the First International Conference on Immunopharmacology, July 1980, Brighton, England

Editors: J. Hadden L. Chedid P. Mullen
eBook ISBN: 9781483145396
Imprint: Pergamon
Published Date: 1st January 1981
Page Count: 528
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Advances in Immunopharmacology documents the proceedings of the First International Conference on Immunopharmacology held in Brighton, England, in July 1980. The volume contains 60 papers organized into 10 parts. The papers in Part I examine the pharmacology of immunotherapeutic drugs and immunotoxicology. Part II presents studies on thymic hormones. Part III is devoted to immunopharmacologic approaches to diseases other than cancer. Part IV deals with mechanisms of chemotaxis degranulation and microbicidal action. Part V focuses on cancer immunopharmacology and immunotherapy while Part VI covers the mechanisms of inflammatory and allergic processes. Part VII takes up the immune testing of the actions of immunotherapeutic agents. Part VIII discusses prostaglandins and macrophage suppression. Part IX is devoted to selected topics such as mechanism of action of soluble immune response suppressor and new approaches to the therapy of allergic diseases. Part X presents discussions during the therapy communication sessions.

Table of Contents

Pharmacology of Immunotherapeutic Drugs and Immunotoxicology

Immuno-Enhancement and Drug Elimination Kinetics In Vivo

Immunostimulants and Hepatic Drug Metabolism

Effects of Interferon Inducers and Viral Infection on the Metabolism of Drugs

The Pharmacologic Properties of Various Forms of Interferon

The Pharmacokinetics of Immunoregulating Drugs: Immunopharmacokinetic

Assessment of Immunotoxicity Induced by the Environmental Chemicals 2, 3, 7, 8-Tetrachlorodibenzo-P-Dioxin, Diethylstilbestrol and Benzo(a)Pyrene

On the Heterogeneity of Immunotherapeutic Agents

Thymic Hormones

A Multifaceted Role for Thymosin and its Composite Peptides in T-cell Regulation

The Effect of the Serum Thymic Factor (FTS) on Suppressor T-cells

The Influence of Thymic Humoral Factor on Immunoproliferative Disorders and Viral Infections in Humans

Immunopharmacologic Approaches to Diseases Other than Cancer

Virus Induced Immunomodulation

Immunopharmacologic Approaches to Bacterial Infection

Immunopotentiation in Experimental Viral Infections

Immunologic Therapy of Viral Infections

Effects of Sex Hormones on Spontaneous Autoimmune Disease in NZB/NZW Hybrid Mice

Immunopharmacologic Therapy of Connective Tissue Diseases

Immunopharmacologic Therapy of Immunodeficiency

Mechanisms of Chemotaxis Degranulation and Microbicidal Action

Early Biochemical Responses of the Neutrophil to Chemoattractants

Complement-Derived Chemotractic Factors

Modification of Rat Polymorphonuclear Chemotaxis by Five Immunomodulators

Use of Visual Analysis to Distinguish the Level of Action of Drugs Neutrophil Chemotaxis and Locomotion

Receptors and Transductional Events in Leukocyte Chemotaxis

Mechanisms of Degranulation

Oxygen-Dependent Cytotoxic Activity of Phagocytes

Cancer Immunopharma Cology and Immunotherapy

Immunological and Tumor Responses to Various Immunotherapeutic Agents

Current Status of Human Cancer Immunotherapy

Specific Active Immunization against Cell Surface Antigens of Human Malignant Melanoma: Development of An Approach

Mechanisms of Inflammatory and Allergic Processes

Non-Specific Inflammation and Host Resistance against Pathogens

Influence of An Acute Non-Immunological Inflammation on Resistance to Infection and Neoplasia

Immunopharmacology of Graft Rejection

Autacoids as Modulators of the Immune Process: A Possible Therapeutic Strategy

Immunopharmacologic Approaches to the Treatment of Allergy

Immune Testing of the Actions of Immunotherapeutic Agents

Resistance Models for the Testing of Immunopotentiating Agents

The Assessment of the Immunotoxicity of Xenobiotics. Experience with Tetrachlorodibenzodioxin and Saccharin

Attempt at Functional Classification of Chemically-Defined Immunomodulators

The Immunopharmacology of Immunotherapy: An Update

Prostaglandins and Macrophage Suppression

Modulation of the PMN Leukocyte Component of Hypersensitivity

Reactions by Lipoxygenase Products of Arachidonic Acid

Arachidonic Acid and Related Fatty Acids in Leukocyte Modulation

Generation of PGD2 and Release of Granule-Associated Mediators by Mast Cells

Axachidonate and Metabolites in Mitogen Activation of Lymphocyte Guanylate Cyclase

Prostaglandins and Macrophage Suppression

Prostaglandins in Lymphocyte Suppressor Mechanisms

Selected Topics

Immunopharmacologic Approaches to Delineation of the Mechanism of Cell-Mediated Cytotoxicity Using Cytotoxic T Cell Clones

Mechanism of Action of Soluble Immune Response Suppressor (SIRS)

Diagnostic and Therapeutic Uses of Monoclonal Antibodies

New Approaches to the Therapy of Allergic Diseases

Lymphocyte Activating Property of Human Leukocytic Pyrogen

The Central Nervous System and Immune Responses: Conditioned Immunopharmacologic Effects

Immunopharmacology of Schistosomiasis

Therapy Communication Sessions

Mycobacteria, C. parvum and Related Substances

Interferon Inducers

Immunopotentiators I

Immunopotentiators II


Polysaccharides and Related Substances I

Polysaccharides and Related Substances II

New Immunosuppressive Agents and Approaches

New Host Modifying Drugs

Muramyl Dipeptide Immunoadjuvants

Lymphokine and Transfer Factor

Author Index

Subject Index


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© Pergamon 1981
eBook ISBN:

About the Editor

J. Hadden

L. Chedid

Affiliations and Expertise

Institute Pasteur, Paris, France

P. Mullen

Ratings and Reviews