Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

Key Features

Key features:

* Contributions from leading authorities
* Informs and updates on all the latest developments in the field


Immunologists and infectious disease specialists, cell biologists and hematologists.

Table of Contents

  1. Regulation of Immunoglobulin Class Switch Recombination: Choreography of Non-Coding Transcription, Targeted DNA Deamination and Long-Range DNA Repair
    Allysia Matthews, Simin Zheng, Lauren DiMenna and Jayanta Chaudhuri
  2. Two Forms of Adaptive Immunity in Vertebrates: Similarities and Differences
    Masanori Kasahara and Yoichi Sutoh
  3. Recognition of Tumors by the Innate Immune System and Natural Killer Cells
    Assaf Marcus, Benjamin G. Gowen, Thornton W. Thompson, Alexandre Iannello, Michele Ardolino, Weiwen Deng, Lin Wang, Nataliya Shifrin and David H. Raulet
  4. Signaling Circuits in Early B Cell Development
    Michael Reth and Peter Nielsen
  5. Interleukin 10 Receptor Signaling: Master Regulator of Intestinal Mucosal Homeostasis in Mice and Humans
    Dror S. Shouval, Jodie Ouahed, Amlan Biswas, Jeremy A. Goettel, Bruce Horwitz, Alexio M. Muise and Scott B. Snapper
  6. Development of Mast Cells and Importance of their Tryptase and Chymase Serine Proteases in Inflammation and Wound Healing
    Jeffrey Douaiher, Julien Succar, Luca Lancerotto, Michael F. Gurish, Dennis P. Orgill, Matthew J. Hamilton, Steven A. Krilis and Richard L. Stevens
  7. Why does Somatic Hypermutation by AID Require Transcription of its Target Genes?
    Ursula Storb


No. of pages:
© 2014
Academic Press
Print ISBN:
Electronic ISBN:

About the editor

Frederick Alt

Affiliations and Expertise

Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA


"The series which all immunologists need."--THE PHARMACEUTICAL JOURNAL

"Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions."--SCIENCE

"Deserves a permanent place in biomedical libraries as an aid in research and in teaching."--JOURNAL OF IMMUNOLOGICAL METHODS