Advances in Immunology - 1st Edition - ISBN: 9780124105249, 9780124105454

Advances in Immunology, Volume 117

1st Edition

Editors: Frederick Alt
Hardcover ISBN: 9780124105249
eBook ISBN: 9780124105454
Imprint: Academic Press
Published Date: 9th May 2013
Page Count: 160
Tax/VAT will be calculated at check-out
146.00
117.00
193.00
Unavailable
Compatible Not compatible
VitalSource PC, Mac, iPhone & iPad Amazon Kindle eReader
ePub & PDF Apple & PC desktop. Mobile devices (Apple & Android) Amazon Kindle eReader
Mobi Amazon Kindle eReader Anything else

Institutional Access


Table of Contents

Series Page

Contributors

Chapter One. Mechanisms of Epigenetic Regulation of Leukemia Onset and Progression

1 Introduction

2 Aberrant DNA Methylation in Leukemia

3 Disruption of Histone-Modifying Complexes Polycomb and MLL in Leukemia

4 Other Epigenetic Writers, Erasers, and Readers

5 Novel Aspects and Technologies in Epigenetics: Implications for Leukemia

Chapter Two. Translocations in Normal B Cells and Cancers: Insights from New Technical Approaches

1 Mechanistic Elements that Generate Chromosomal Translocations

2 Novel High-Throughput Methods to Study Chromosomal Translocations

3 New Findings on Translocation Formation Obtained by HTGTS and TC-Seq

4 Landscape of Translocations in Cancers

5 Perspectives

Chapter Three. The Intestinal Microbiota in Chronic Liver Disease

1 Introduction

2 Role of the Intestinal Microbiota on Chronic Liver Diseases

3 Role of the Interactions Between the Innate Immune System and the Intestinal Microbiota on Chronic Liver Diseases

4 Probiotics and their Potential Role in Liver Disease Therapy

5 Conclusions

Chapter Four. Intracellular Pathogen Detection by RIG-I-Like Receptors

1 General Principles of the Antiviral Innate Immune Response

2 RLRs are RNA Sensors

3 RIG-I Activation and Receptor Proximal Signal Propagation

4 Regulatory Mechanisms of RIG-I Signaling

5 Conclusions and Future Directions

Index

Contents of Recent Volumes


Description

Series Page

Contributors

Chapter One. Mechanisms of Epigenetic Regulation of Leukemia Onset and Progression

1 Introduction

2 Aberrant DNA Methylation in Leukemia

3 Disruption of Histone-Modifying Complexes Polycomb and MLL in Leukemia

4 Other Epigenetic Writers, Erasers, and Readers

5 Novel Aspects and Technologies in Epigenetics: Implications for Leukemia

Chapter Two. Translocations in Normal B Cells and Cancers: Insights from New Technical Approaches

1 Mechanistic Elements that Generate Chromosomal Translocations

2 Novel High-Throughput Methods to Study Chromosomal Translocations

3 New Findings on Translocation Formation Obtained by HTGTS and TC-Seq

4 Landscape of Translocations in Cancers

5 Perspectives

Chapter Three. The Intestinal Microbiota in Chronic Liver Disease

1 Introduction

2 Role of the Intestinal Microbiota on Chronic Liver Diseases

3 Role of the Interactions Between the Innate Immune System and the Intestinal Microbiota on Chronic Liver Diseases

4 Probiotics and their Potential Role in Liver Disease Therapy

5 Conclusions

Chapter Four. Intracellular Pathogen Detection by RIG-I-Like Receptors

1 General Principles of the Antiviral Innate Immune Response

2 RLRs are RNA Sensors

3 RIG-I Activation and Receptor Proximal Signal Propagation

4 Regulatory Mechanisms of RIG-I Signaling

5 Conclusions and Future Directions

Index

Contents of Recent Volumes

Key Features

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field

Readership

Immunologists and infectious disease specialists, cell biologists and hematologists


Details

No. of pages:
160
Language:
English
Copyright:
© Academic Press 2013
Published:
Imprint:
Academic Press
eBook ISBN:
9780124105454
Hardcover ISBN:
9780124105249

Reviews

"The series which all immunologists need." --The Pharmaceutical Journal

"Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions." --Science

"Deserves a permanent place in biomedical libraries as an aid in research and in teaching." --Journal of Immunological Methods


About the Editors

Frederick Alt Editor

Affiliations and Expertise

Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA