Advances in Immunology

Advances in Immunology

1st Edition - December 1, 2022

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  • Editor: Frederick Alt
  • Hardcover ISBN: 9780323989473

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Advances in Immunology, Volume 156, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, with this volume covering Regulatory T Cells in Infection and Factor H and Properdin and their regulation.

Key Features

  • Presents current developments and comprehensive reviews in immunology
  • Provides the latest in a longstanding and respected serial on the subject matter
  • Focuses on recent advances in the advancing area of the mechanisms involved in the evolution of regulatory T-cells in infection and Factor H and Properdin and their regulation


Immunologists and infectious disease specialists, cell biologists and hematologists

Table of Contents

  • 1. CARD8 inflammasome in HIV infection
    Liang Shan
    2. Chapter title to be determined
    Patrick Hogan
    3. Antigen receptor structure and signaling
    Zhiwei Huang
    4 Tregs in the brain" or "T cell tolerance and exhaustion by NR4a nuclear factor
    Akihiko Yoshimura
    5. C-type lectin receptors and innate recognition
    Sho Yamasaki
    6. A mRNA modifications in the immune system
    Li Li and Richard Flavell
    7. Genetic Susceptibility to autoimmunity
    Xi Huji
    8. Activation and regulation of the cGAS-STING pathway
    Zhengfan Jiang

Product details

  • No. of pages: 198
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: December 1, 2022
  • Imprint: Academic Press
  • Hardcover ISBN: 9780323989473

About the Editor

Frederick Alt

Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.

Affiliations and Expertise

Investigator and Director of the Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA

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