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1. The design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies
2. T cells in latent viral infections
3. Preserving Immune Homeostasis with A20
4. Transcriptional control in the context of innate and adaptive lymphoid development
5. RAG and AID structural biology and the important insights it has generated for the V(D)J recombination and CSR/SHM fields
6. The advancing area of the mechanisms involved in the evolution of HIV-1 neutralizing antibodies
7. Normal Microbiota inducing disease
8. Plasma Cell Sub-populations
Advances in Immunology, Volume 146, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release focusing on The design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies, T cells in latent viral infections, Preserving Immune Homeostasis with A20, Transcriptional control in the context of innate and adaptive lymphoid development, RAG and AID structural biology and the important insights it has generated for the V(D)J recombination and CSR/SHM fields, and more.
- Presents current developments and comprehensive reviews in immunology
- Provides the latest in a longstanding, respected serial on the subject matter
- Focuses on recent advances in the advancing area of the mechanisms involved in the evolution of HIV-1 neutralizing antibodies
Immunologists and infectious disease specialists, cell biologists and hematologists
- No. of pages:
- © Academic Press 2020
- 1st May 2020
- Academic Press
- Hardcover ISBN:
Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.
Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA