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Advances in Immunology - 1st Edition - ISBN: 9780128022450, 9780128024331

Advances in Immunology, Volume 127

1st Edition

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Editor: Frederick Alt
Hardcover ISBN: 9780128022450
eBook ISBN: 9780128024331
Imprint: Academic Press
Published Date: 1st June 2015
Page Count: 332
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Table of Contents

  1. Cross-Presentation in Mouse and Human Dendritic Cells
    Elodie Segura and Sebastian Amigorena
  2. HLA-G: An Immune Checkpoint Molecule
    Edgardo D. Carosella, Nathalie Rouas-Freiss, Diana Tronik-Le Roux, Philippe Moreau and Joel LeMaout
  3. Activation and Function of iNKT and MAIT Cells
    Shilpi Chandra and Mitchell Kronenberg
  4. IgE and Mast Cells: the Endogenous Adjuvant
    Hans C. Oettgen and Oliver T. Burton
  5. RNA Exosome Regulates AID DNA Mutator Activity in the B Cell Genome
    Evangelos Pefanis and Uttiya Basu


Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

Key Features

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field


Immunologists and infectious disease specialists, cell biologists and hematologists.


No. of pages:
© Academic Press 2015
1st June 2015
Academic Press
Hardcover ISBN:
eBook ISBN:

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About the Editor

Frederick Alt

Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.

Affiliations and Expertise

Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA