Advances in Immunology - 1st Edition - ISBN: 9780128022436, 9780128024317

Advances in Immunology, Volume 125

1st Edition

Serial Editors: Frederick Alt
eBook ISBN: 9780128024317
Hardcover ISBN: 9780128022436
Imprint: Academic Press
Published Date: 8th January 2015
Page Count: 206
Sales tax will be calculated at check-out Price includes VAT/GST
30% off
30% off
30% off
30% off
30% off
30% off
30% off
30% off
30% off
30% off
30% off
30% off
Price includes VAT/GST
× DRM-Free

Easy - Download and start reading immediately. There’s no activation process to access eBooks; all eBooks are fully searchable, and enabled for copying, pasting, and printing.

Flexible - Read on multiple operating systems and devices. Easily read eBooks on smart phones, computers, or any eBook readers, including Kindle.

Open - Buy once, receive and download all available eBook formats, including PDF, EPUB, and Mobi (for Kindle).

Institutional Access

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Table of Contents

  • Chapter One: Regulation of CD4 and CD8 Coreceptor Expression and CD4 Versus CD8 Lineage Decisions
    • Abstract
    • 1 Introduction
    • 2 CD4 and CD8 Coreceptors and Thymocyte Selection
    • 3 Cis-Regulatory Elements for Genes Encoding CD4 and CD8 Coreceptors
    • 4 Transcription Factors Regulating CD4 and CD8 Expression and Lineage Choice in the Thymus
    • 5 Regulation of CD4 and CD8 in Mature T Cells
    • 6 Cytokine Receptor Signals and CD4/CD8 Lineage Commitment
    • 7 Concluding Remarks
    • Acknowledgments
  • Chapter Two: Mast Cells’ Integrated Actions with Eosinophils and Fibroblasts in Allergic Inflammation: Implications for Therapy
    • Abstract
    • 1 Introduction
    • 2 Mast Cells and Eosinophils in Allergic Inflammation
    • 3 Mast Cell Eosinophil Cross-Talk: The Allergic Effector Unit
    • 4 Fibroblasts from Repair to Fibrosis in Allergic Inflammation
    • 5 Mast Cells and Fibroblasts: Bidirectional Interactions
    • 6 Eosinophls and Fibroblasts: Bidirectional Interactions
    • 7 Therapeutic Implications of Mast Cells, Eosinophils, and Fibroblasts Cross Talks for Allergic Inflammation
    • 8 Future Drugs
    • 9 Conclusions
    • Acknowledgments
  • Chapter Three: Positive-Selection-Inducing Self-Peptides Displayed by Cortical Thymic Epithelial Cells
    • Abstract
    • 1 Introduction
    • 2 Characterization of Positive-Selection-Inducing Peptides
    • 3 Antigen Processing in Cortical Thymic Epithelial Cells
    • 4 Concluding Remarks
    • Acknowledgment
  • Chapter Four: Group 2 Innate Lymphoid Cells in the Regulation of Immune Responses
    • Abstract
    • 1 Introduction
    • 2 Meet the Family
    • 3 Drawing Parallels Between ILC Cells and T Cells
    • 4 Human and Murine ILC2 Cell Phenotypes
    • 5 ILC2 Cell Development
    • 6 The Cytokine Factory
    • 7 Sensing of the Environment by ILC2 Cells
    • 8 The Black Sheep of the Family: The Dermal ILC2 Cell
    • 9 Are ILC2 Cells Upstream or Downstream of T Cells?
    • 10 Concluding Remarks
  • Chapter Five: Microbes and B Cell Development
    • Abstract
    • 1 Microbiota
    • 2 Early-Life B Cell Development and the Gut
    • 3 Microbial Influence on Immunoglobulin Production
    • 4 B Lineage Cell Influence on Commensal Microbe Ecology
    • 5 Concluding Remarks
    • Acknowledgments
  • Index
  • Contents of Recent Volumes


Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

Key Features

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field


Immunologists and infectious disease specialists, cell biologists and hematologists.


No. of pages:
© Academic Press 2015
Academic Press
eBook ISBN:
Hardcover ISBN:


"The series which all immunologists need."--THE PHARMACEUTICAL JOURNAL

"Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions."--SCIENCE

"Deserves a permanent place in biomedical libraries as an aid in research and in teaching."--JOURNAL OF IMMUNOLOGICAL METHODS

Ratings and Reviews

About the Serial Editors

Frederick Alt Serial Editor

Affiliations and Expertise

Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA