Advances in Immunology

Advances in Immunology

1st Edition - June 10, 2010

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  • Editor: Frederick Alt
  • eBook ISBN: 9780123813039

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Description

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future.

Key Features

  • Contributions from leading authorities and industry experts
  • Informs and updates on all the latest developments in the field

Readership

Immunologists and infectious disease specialists, cell biologists and hematologists

Table of Contents

    1. Learning from leprosy: insight into the human innate immune response

    Dennis Montoya and Robert L. Modlin

    2. The immunological functions of saposins

    Alexandre Darmoise, Patrick Maschmeyer and Florian Winau

    1. OX40-OX40 ligand interaction in T cell-mediated immunity and immunopathology

    Naoto Ishii, Takeshi Takahashi, Pejman Soroosh, and Kazuo Sugamura

    4.The family of IL-10-secreting CD4+ T cells

    Keishi Fujio, Tomohisa Okamura, and Kazuhiko Yamamoto

     

    5.Artificial engineering of secondary lymphoid organs

    Jonathan K.H. Tan and Takeshi Watanabe

    6. Aid And Somatic Hypermutation

    Robert W. Maul and Patricia J. Gearhart

    7. BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis

    Katia Basso and Riccardo Dalla-Favera

     

Product details

  • No. of pages: 236
  • Language: English
  • Copyright: © Academic Press 2010
  • Published: June 10, 2010
  • Imprint: Academic Press
  • eBook ISBN: 9780123813039

About the Editor

Frederick Alt

Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.

Affiliations and Expertise

Investigator and Director of the Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA

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