Advances in Immunology, Volume 97

1st Edition

Editors: Frederick Alt
Hardcover ISBN: 9780123743244
eBook ISBN: 9780080879017
Imprint: Academic Press
Published Date: 11th June 2008
Page Count: 312
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Table of Contents

    <li>Contributors to Volume 97<ul><li>Publisher Summary</li></ul></li> <li>T Cell Activation and the Cytoskeleton: You Can't Have One Without the Other<ul><li>Abstract</li><li>1 Introduction</li><li>2 TCR Signaling Leading to Actin Cytoskeletal Remodeling</li><li>3 Cytoskeletal Control of IS Formation</li><li>4 Regulation of TCR&#x2010;Mediated MTOC Polarization</li><li>5 F&#x2010;Actin&#x2010;Mediated Regulation of Integrins</li><li>6 Cytoskeletal Dynamics and Cell Migration</li><li>7 Conclusion</li></ul></li> <li>HLA Class II Transgenic Mice Mimic Human Inflammatory Diseases<ul><li>Abstract</li><li>1 Introduction</li><li>2 Expression and Function of HLA&#x2010;DQ Transgenes in Mice</li><li>3 HLA&#x2010;DQ Transgenic Mice as Models for Human Allergies</li><li>4 Expression and Function of HLA&#x2010;DR Transgenic Mice</li><li>5 HLA Class II Transgenic Mice Identify the Same Determinants of M. Tuberculosis&#x2010;Derived Proteins as Humans</li><li>6 Collagen&#x2010;Induced Arthritis&#x2014;Model for Human Rheumatoid Arthritis</li><li>7 Experimental Autoimmune Encephalomyelitis: A Model for Multiple Sclerosis</li><li>8 Spontaneous Models for Human Type I Diabetes</li><li>9 Experimental Autoimmune Myasthenia Gravis</li><li>10 HLA and Gluten Sensitivity&#x2010;Celiac Disease and Dermatitis herpetiformis</li><li>11 Relapsing Polychondritis</li><li>12 Spontaneous Autoimmune Myocarditis</li><li>13 Experimental Autoimmune Thyroiditis (Adapted from Kong et al., 2007)</li><li>14 Experimental Autoimmune Uveitis (Adapted fromPennesi et al., 2003)</li><li>15 Bacterial Superantigens and Toxic Shock Syndrome</li><li>16 Concluding Remarks</li></ul></li> <li>Roles of Zinc and Zinc Signaling in Immunity: Zinc as an Intracellular Signaling Molecule<ul><li>Abstract</li><li>1 Introduction</li><li>2 Zn Homeostasis, Zn Transporters, and Metallothioneins in Health and Disease</li><li>3 Role of Zn in the Immune Response</li><li>4 Role of Zn in Mast Cells<


Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.


Immunologists and infectious disease specialists, cell biologists and hematologists


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© Academic Press 2008
Academic Press
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About the Editors

Frederick Alt Editor

Affiliations and Expertise

Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA